Sulfasalazine Flashcards
(8 cards)
1
Q
Sulfasalazine indications
A
Treatment of acute attacks or mild- severe UC
active crohns
Maintenance of remission of mild-severe UC
Active RA
2
Q
What colour can sulfasalzine discolour bodily fluids
A
Yellow
3
Q
CI of sulfasalazine
A
Aspirin sensitivity
4
Q
Sulfasalazine in renal impairment
A
Avoid in severe
Risk of toxicity in moderate
5
Q
Sulfasalazine monitoring requirements
A
Liver function
Renal function
FBC
Monthly for first 3 months
6
Q
Sulfasalazine in pregnancy requirement
A
Folate supplementation. Sulfasalazine inhibits absorption and metabolism of folic acid
7
Q
MHRA sulfasalazine
A
BLOOD DISORDERS
HEPATOXICITY
8
Q
Interactions of sulfasalzine
A
Avoid hepatotoxic (doxy, carbamazepine) and myelosuppresent medicines (ethosuximide, methotrexate)
