Practice Questions set 1 Flashcards

1
Q

A patient was just admitted to a long-term care facility from the local hospital. The patient is being treated for psoriasis. The psoriasis does not appear to be responding to treatment, and 48 hours later, the Infection Preventionist (IP) receives a report that a Certified Nursing Assistant has developed an itchy rash. The patient’s physician visits and determines that the patient has crusted scabies and not psoriasis. Another name for crusted scabies is:

a. American scabies
b. Norwegian scabies
c. Canadian scabies
d. English scabies

A

Norwegian scabies is a severe form of scabies that can occur in individuals who may be immunocompromised, elderly, disabled, or debilitated.

Chapter 99 in APIC 2008 on Parasites.

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2
Q

Guidelines for transporting specimens include:

1) Transport within 2 hours of collecting a specimen.
2) Transport in a leak proof specimen containers and sealable leak proof bags.
3) Transport specimen in the syringe used to collect it.
4) Refrigerate all specimens prior to transport.
a) 1,4. b) 2,3. c) 1,2. d) 3,4

A

Transport within 2 hours of collecting a specimen.

Transport in a leak proof specimen containers and sealable leak proof bags.

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3
Q

Which is True about a tuberculin skin test (TST):

a. Positive TST indicates active tuberculosis infection.
b. Negative TST rules out active TB infection.
c. Positive TST indicates past exposure to TB.
d. Negative TST indicates past exposure to TB.

A

Positive TST indicates past exposure to TB.

TST involves injection of purified protein derived from the mycobacterial cell wall.

APIC chapter 95 Tuberculosis and Other Mycobacteria

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4
Q

The optimal time to collect a sputum specimen for acid-fast bacilli (AFB) testing to rule out TB would be:

a. First thing in the morning.
b. After a respiratory treatment.
c. Prior to the patient going to bed.
d. Prior to a respiratory treatment.

A

First thing in the morning.

Because pulmonary disease is the most common form of TB, patients with suspected TB should have a chest radiograph.

APIC chapter 95 Tuberculosis and Other Mycobacteria

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5
Q

A hospital has hired a new manager of the Microbiology section of the laboratory. During the initial discussion with the manager about the Infection prevention and control program, the IP stresses the importance of collaboration between the departments in reducing healthcare-associated infections (HAIs). Of the choices below, which activity will best meet this goal?

a. The Microbiology staff’s compliance with the annual flu vaccination program and tuberculosis skin testing.
b. The Microbiology staff’s participation in the periodic infection prevention educational sessions for hospital staff.
c. Microbiology’s prompt notification to the Infection prevention and control department of any organism’s unusual resistance pattern.
d. The Microbiology manager’s attendance at local, state and / or national infection prevention and control educational conferences.

A

Microbiology’s prompt notification to the Infection prevention and control department of any organism’s unusual resistance pattern.

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6
Q

The primary immune response after exposure to a communicable disease pathogen or vaccine is production of:

a. Immunoglobulin G (IgG)
b. Immunoglobulin M (IgM)
c. Immunoglobulin A (IgA)
d. Immunoglobulin C (IgC)

A

Immunoglobulin M (IgM)

During the primary immune response that occurs after a communicable disease pathogen or vaccine is encountered, the class of antibody that is produced first is IgM. IgG develop a few weeks later and are a good indication of the convalescence period and generally mark the establishment of long-term immunity to the pathogen.

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7
Q

When are IgM antibodies to Hepatitis A virus (HAV detectable in the blood?

a. 30 days after exposure.
b. 5 to 10 days after exposure.
c. 1 to 4 days after exposure.
d. 15 - 20 days after exposure.

A

5 to 10 days after exposure.

Hepatitis A is an acute liver disease caused by HAV. Clinical features of acute hepatitis are not specific for HAV infection, so serological diagnosis is necessary. IgM antibodies to HAV (IgM anti-HAV), which are used to diagnose acute HAV infection are detectable with in 3 weeks of exposure and are present a the onset of jaundice.

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8
Q

The incubation period for pertussis in immunocompetent persons is usually:

a. 7 to 10 days.
b. 3 to 5 days.
c. 1 to 2 days.
d. 2 to 4 days.

A

7 to 10 days.

Pertussis is a highly communicable, acute infectious respiratory disease caused by Bordetella pertussis. The incubation period in immunocompromised patients is usually 7 to 10 days, with a range of 6 to 21 days. In rare cases, the incubation period may be as long as 42 days.

APIC chapter 71 Bordetella pertussis

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9
Q

A patient who was hospitalized for 2 days calls 3 days after discharge complaining that he has developed healthcare-associated scabies due to his recent inpatient stay. The IP knows that his scabies infestation is not healthcare-associated because:

a. Scabies is only transmitted through contaminated linens.
b. The incubation period for scabies is longer than 5 days.
c. The incubation period for scabies is shorter than 3 days.
d. Scabies is only transmitted through direct contact and none of the healthcare personnel who cared for the patient are infested.

A

The incubation period for scabies is longer than 5 days.

It may be as short as 10 days but is typically between 4 to 6 weeks. Therefore, the patient could not have acquired scabies during the hospital stay because, based on the incubation period, he would need to have been exposed at least 5 days before he was admitted.

APIC chapter 99 parasites

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10
Q

A nurse is concerned that a patient in the neurology ward has a prion disease after receiving a lab report stating that the patient had a positive nucleic acid test for John Cunningham virus (JCV) in the cerebrospinal fluid. What is the best response to give this nurse?

a. The test is positive for Creutzfeldt-Jakob disease, which is a prion disease.
b. The test is positive for Camphlobactor jejuni, which is not a prion disease.
c. The test is positive for JCV (a polyomavirus, which is not a prion disease.
d. the test is positie for JCV ( a polyomavirus ), which is a prion disease.

A

The test is positive for JCV (a polyomavirus), which is not a prion disease.

JCV is a polyomavirus that can cause a demyelinating disease called progressive multifocal leukoencephalopathy in immunocompromised patients. Because the name and some presenting symptoms, JCV is sometimes confused with CJD, which is a prion disease.

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11
Q

An IP is conducting an educational session to help the nursing staff understand infectious disease transmission. She explains that the initial element in virulence is the ability of an organism to survive in the external environment during transit between hosts. What is the second element of virulence?

a. Secretion of enzymes that enhance spread through tissues.
b. A mechanism for transmission to a new host.
c. invasion and dissemination in the host.
d. Avoidance of host resistance.

A

A mechanism for transmission to a new host.
The second element in virulence is a mechanism for transmission to a new host.

APIC chapter 22 Microbial pathogenicity and host response

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12
Q

The Management of an infected surgical site includes the following foundational principles:

1) Open and drain the incision
2) Debride fibrous debris and necrotic soft tissue
3) Replace hardware
4) Implement antimicrobial management as needed
5) Manage the open wound

a. 1,2,3,4
b. 2,3,4,5
c. 1,3,4,5
d. 1,2,4,5

A

Open and drain the incision
Debride fibrous debris and necrotic soft tissue
Implement antimicrobial management as needed
Manage the open wound

APIC chapter 37 surgical site infection

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13
Q

During annual TST, an employee’s test result was read as 10mm induration. The employee’s last TST was negative. This initial result indicates a:

a. Positive test.
b. False positive.
c. Negative test.
d. False negative

A

positive test is determined by the number of mm of induration (Not erythema) caused by the reaction to the tuberculin.

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14
Q

A microbe that can grow in the absence of oxygen but is also able to utilize oxygen for growth is a/an:

a. Aerobe.
b. Obligate anaerobe.
c. Facultative anaerobe.
d. Microaerophilic aerobe

A

Facultative anaerobe will utilize oxygen if it is present but are still able to grow in the absence of oxygen.

Ready APIC chapter Microbiology Basics (chapter 24)

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15
Q

Western blot testing for human immunodeficiency virus (HIV) is used to detect:

a. HIV DNA in a serum sample.
b. HIV RNA in a serum sample.
c. HIV antibodies in a serum sample.
d. HIV proteins in a serum sample

A

antibodies in a serum sample.
Western blot is a confirmatory test that is performed on all samples that have tested positive for HIV on enzyme immunoabsorbent assay (EIA).

APIC text HIV/AIDS (Chapter 81)

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16
Q

An infection preventionist (IP) is reviewing the cerebrospinal fluid (CSF) results from a patient admitted the previous night. The CSF is cloudy and has an elevated WBC, markedly increased neutrophils, low glucose level and elevated protein concentration. What type of meningitis should she suspect?

a. Bacterial.
b. Viral.
c. Fungal.
d. Aseptic

A

Bacterial

The diagnosis of bacterial meningitis rests on examination of the CSF

APIC Laboratory Testing and diagnosis (Chapter 25)

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17
Q

Which of the following statements about influenza is false?

a. Influenza is primarily spread between individuals via respiratory secretions (droplets)
b. Viral shedding starts 48 to 72 hours after infection and typically 48 hours before the onset of symptoms.
c. Viral shedding normally persists for less than 5 days but can be longer in children and in immunocompromised persons.
d. The typical influenza symptomology is not always predictive of influenza in elderly or immunocompromised persons.

A

Viral shedding starts 48 to 72 hours after infection and typically 48 hours before the onset of symptoms.

Influenza viruses are spread from person to person primarily through large-particles respiratory droplet transmission.

APIC text Influenza (Chapter 82)

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18
Q

Which of the following statements is false regarding influenza viruses?

a. They are divided into three categories: A, B, and C
b. Influenza A strains have been the predominant cause of worldwide epidemics (pandemics)
c. Influenza A and B strains have been named according to the city or state and year of their initial isolation.
d. Influenza B strains have not been associated with large epidemics.

A

Influenza B strains have not been associated with large epidemics

APIC text Influenza (Chapter 82)

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19
Q

Which factor is commonly associated with Clostridium difficile infections? (CDI).

a. Chemotherapeutic agents
b. ACE inhibitors
c. Prophylactic antibiotics or antibiotic to treat a primary bacterial infection.
d. Antiviral medication to treat a primary viral infection

A

Prophylactic antibiotics or antibiotic to treat a primary bacterial infection.

C-diff is a spore-forming, Gram-positive anaerobic bacillus that produces two exotoxins: toxin A and toxin B. It is a common cause of antibiotic-associated diarrhea (AAD). It accounts for 15-25 percent of all episodes of AAD.

APIC text Clostridium difficile infection and Pseudomembranous Colitis (Chapter 72)

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20
Q

The IP is reviewing the history of a patient who has been in the facility on a ventilator for a week. All of the following are risk factors for colonization and infection with multidrug-resistant pathogens except:

a. Antimicrobial therapy in preceding 90 days.
b. Current hospitalization of 5 days or more.
c. Immunosuppressive state or therapy.
d. Low frequency of antibiotic resistance in the facility.

A

Low frequency of antibiotic resistance in the facility.

Pneumonia may be caused by a wide variety of pathogens, but multidrug-resistant organisms (MDRO) are becoming more relevant as etiologic agents.

APIC text Pneumonia (Chapter 36)

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21
Q

The current community-acquired pneumonia (CAP) national quality measures used in the United States include all of the following except:

a. Antibiotic timing (within 6 hours of arrival)
b. Antibiotic selection
c. Blood cultures performed in the Emergency Department before antibiotics were administered.
d. Ensure that all patients are screened for pneumococcal vaccination.

A

Ensure that all patients are screened for pneumococcal vaccination.

The core quality measures are a set of standards defined by the Joint Commission and CMS to create core measures for disease management for CAP.

APIC text Pneumonia (Chapter 36)

22
Q

Measures that can be practiced for prevention of aspiration include all of the following except:

a. antibiotic prophylaxis
b. Oropharyngeal cleaning and decontamination with an aseptic agent (e.g., chlorhexidine)
c. Orotracheal intubation, unless contraindicated, rather than nasotracheal intubation
d. The head of the bed elevated at an angle of 30 - 45 degrees

A

Antibiotic prophylaxis

see APIC text Pneumonia (Chapter 36)

23
Q

The paroxysmal stage of pertussis usually lasts:

a. 1 to 6 weeks
b. 11 to 15 weeks
c. 15 to 20 weeks
d. 6 to 21 weeks

A

1 to 6 weeks

APIC text (Chapter 71)

24
Q

Which of the following is not an effect of malnutrition on the body’s immune system?

a. Intestinal bacteria may be altered
b. Tissue integrity is impaired
c. Mucosal secretions are decreased
d. Urine may be colonized with bacteria

A

Urine may be colonized with bacteria

Malnutrition affects with body’s immune system by altering the intestinal bacteria, impairing the integrity of the tissue, and decreasing mucosal secretions.

APIC text Nutrition and Immune Function (Chapter 47)

25
Q

Lyme disease is commonly found in all of the following regions of the United States except:

a. New England
b. Mid-Atlantic
c. Upper Midwest
d. Southeast.

A

Southeast

APIC text Lyme disease (chapter 85)

26
Q

All of the following are descriptions of patients with immunocompromised status EXECPT:

a. HIV with CD4 count less than 200
b. Leukemia or lymphoma
c. Neutropenia (absolute neutrophils count less than 500mm3)
d. 1 year post bone marrow transplant

A

1 year post bone marrow transplant

Patients with immunocompromised status include those with the following:
Neutropenia (less than 500mm3), leukemia or lymphoma, HIV with CD4 count less than 200, Splenectomy, Early post transplant, on cytotoxic chemotherapy, on high dose steroids.

APIC chapter 36 Pneumonia

27
Q

A patient is admitted with pruritic lesions on the hands, webs of fingers, wrists, the extensor surfaces of the elbows and knees, and the outer surfaces of the feet, armpits, buttocks, and waist. The most likely diagnosis is:

a. Scarlet fever
b. Herpes zoster
c. Scabies
d. Measles

A

Scabies

Skin infestations by the mite Sarcoptes scaiei var. hominis are commonly known as scabies. Mites are transmitted via direct contact with infested persons; less frequently through contact with clothes or bedding.

APIC Chapter 99 Parasites

28
Q

Which of the following is NOT likely to contaminate total parenteral nutrition?

a. Mycobacterium fortuitum
b. Candida albicans
c. Psudomonas aeruginosa
d. Staphylococcus epidermidis

A

Mycobacterium fortuitum

With strict adherence to aseptic compounding technique, contamination of the total parental nutrition (TPN) solution is rarely the cause of sepsis. However, TPN can foster microbial growth.

APIC text 47 - Nutrition and Immune Function

29
Q

A urine specimen collected from an indwelling urinary catheter was sent to the laboratory for culture and sensitivity testing. Culture results reported a colony count of 50,000 CFU/mL of Escherichia coli. Sensitivity testing reported resistance to cephalosporin and sensitivity to ciprofloxacin. this organism is an example of:

a. Methicillin resistance
b. Aminoglycoside resistance
c. Extended-spectrum beta-lactam (ESBL) resistance
d. Quinolone resistance

A

Extended-spectrum beta-lactam (ESBL) resistance.

ESBL’s are B-lactamses found in common Gram-negative bacteria such as E.coli and K. pnuemoniae, which confer resistance to all B-lactam drugs except the carbapenems.

APIC Chapter 26 Antimicrobials and Resistance

30
Q

A patient has a nasal swab positive for MRSA in the absence of symptoms, this is an example of:

a. Normal flora
b. Colonization
c. Asymptomatic infection
d. Symptomatic infection

A

Colonization

Colonization is the presence of microorganisms on skin, on mucous membranes, in open wounds, or in excretions or secretions in the absence of adverse clinical signs or symptoms.

APIC Chapter 24 Microbiology basics

31
Q

Which of the following is NOT a mechanical barrier to infection?

a. intact skin
b. Mucous membranes
c. Secretions
d. Cilia

A

Secretions

A biofilm is any group of microorganisms in which cells stick to each other on a surface. These adherent cells are frequently embedded within a self-produced matrix of extracellular polymeric substance.

APIC chapter 70 biofilms

32
Q

Patients with cell-mediated immunity dysfunction are susceptible to infections attributed to pathogenic intracellular bacteria. Examples of these organisms include:

1) Salmonella typhi
2) Bacteroides fragilis
3) Listeria monocytogenes
4) Staphylococcus aureus

a. 2,3
b. 1,3
c. 1,2
d. 3,4

A

Salmonella typhi
Listeria monocytogenes

As a host becomes progressively more immunocompromised, progressively fewer virulent organisms are able to become pathogenic. Thus patients with major immune defects are subject to a larger number and greater variety of infectious diseases.

APIC Chapter 23 The immunocompromised host.

33
Q

What is the name for a substance that prevents water-soluble elements such as antibiotics and disinfectants from reaching pathogens?

a. cell wall
b. biofilm
c. sludge
d. biocarbon

A

Biofilm

A biofilm is any group of microorganisms in which cells stick to each other on a surface. These adherent cells are frequently embedded within a self-produced matrix of extracellular polymeric substance.

APIC Chapter 70 Biofilms

34
Q

A Gram-negative bacterium that is responsible for chronic antral gastritis and is a major factor in peptic ulcer disease is:

a. Streptococcus pyogenes
b. Salmonella typhi
c. Clostridium difficle
d. Helicobacter pylori

A

Helicobacter pylori

H.pylori is a Gram-negative bacterium that causes chronic gastritis in humans. This bacterium is also considered to be a common cause of ulcers worldwide:

35
Q

The spirochete Borrelia burgdorferi is the agent responsible for:

a. Legionnaire’ disease
b. Lyme disease
c. Aseptic meningitis
d. Syphilis

A

Lyme disease

caused by the bacterium Borrelia burgdorferi and is transmitted to humans through the bite of infected black-legged ticks.

APIC Chapter 85 Lyme Disease

36
Q

Higher morbidity rates in chronic hepatitis B virus (HBV) carriers are associated with a co-infection of which of the following:

a. Hepatitis A
b. Hepatitis D
c. Hepatitis C
d. Hepatitis E

A

Hepatitis D
also known as “delta hepatitis”, is a serious liver disease caused by infection with the Hep D virus (HDV), which is an RNA virus structurally unrelated to the Hep A, B, or C viruses.

APIC Chapter 97 Viral Hepatitis

37
Q

Gram stains classify an organism as Gram-positive or Gram-negative. The determinant factors for Gram stains are cell wall components of:

a. Peptidoglycans
b. Lipids
c. Polysaccharides
d. Mycolic acids

A

Peptidoglycan
The Gram stain is the most important and universally used staining technique in the bacteriology laboratory. It is used to distinguish between Gram-positive and Gram-negative bacteria, which have distinct and consistent differences in their cell walls.

APIC Chapter 24 Microbiology Basics

38
Q

An example of an obligate intracellular parasitic bacterium would be an organism responsible for:

1) Hepatitis
2) Q fever
3) Malaria
4) Epidemic typhus

a. 2,3
b. 2,4
c. 3,4
d. 1,2

A

Q fever and Malaria

Intracellular parasites are parasitic microorganisms that are capable of growing and reproducing inside the cells of a host.

39
Q

Which one of the following statements is TRUE regarding bacterial spores?

a. They are resistant to antibiotics
b. They allow the bacteria to multiply in adverse conditions
c. They are usually formed by Gram-negative bacteria
d. They can be identified with Gram stain

A

They are resistant to antibiotics

The function of a spore is to permit the cell to survive unfavorable conditions such as extremes of temperature or moisture.

APIC text - Chapter 24 Microbiology basics

40
Q

Which organism found in food poisoning causes the most rapid onset of symptoms?

a. Salmonella enteritidis
b. Shigella sonnei
c. Staphylococcus aureus
d. Escherichis coli

A

Staphylococcus aureus

Eating foods contaminated with toxins produced by S. aureus causes staphylococcal food poisoning. Food workers who carry Staph and then handle food without washing their hands contaminate foods by direct contact.

APIC chapter 83 Food-borne illnesses

41
Q

The IP is teaching nurses who to assess infection risks in patients. Depletion of what cell type provides the best indication of susceptibility to most bacterial infections?

a. monocyte
b. eosinophil
c. neutrophil
d. lymphocyte

A

Neutrophil
Is the most abundant (40 of 75%) type of white blood cell and are formed from stem cells in the bone morrow.

APIC chapter 22 - Microbial Pathogenicity and Host Response

42
Q

A 14 year old boy from the rural Maryland was seen in the emergency room and fever, fatigue, chills, headache, and a large annular lesion on his left thigh, which the patient described as burning and itching What is the most probable vector of this child’s illness?

a. Tick
b. Mosquito
c. Flea
d. Louse

A

Tick

This child’s symptoms are consistent with Lyme disease. Typical symptoms include fever, headache, and a characteristic skin rash call erythema migrans.

APIC text Chapter 85 Lyme Disease

43
Q

Which immune marker represents past exposure to disease?

a. IgG
b. IgE
c. IgM
d. IgA

A

IgG
is the major circulating and extravascular (interstitial) antibody, IgG is the late - occurring immunoglobulin in an immune response and is the longest lived. IgG represents past exposure to disease.

APIC chapter 22 Microbial Pathogenicity

44
Q

The Emergency Department reports three cases of cramping, abdominal pain, and diarrhea within a 24-hour period. All persons are from the same community, and onset of symptoms was within 12 to 36 hours of a picnic they all attended. The IP suspects which of the following food-borne illnesses:

a. Salmonella
b. Hepatitis A
c. Staphylococcus aureus
d. Clostridium perfringens

A

Salmonella

Most persons infected with Salmonella develop diarrhea, fever, and abdominal cramps 12 to 72 hours after infection.

APIC chapter 83 Food-borne illnesses

45
Q

When reviewing the Gram stain of a person with a wound infection, the IP sees Gram-positive organisms in clusters. Which organism would this most likely represent?

a. Streptococcus
b. Enterococcus
c. Corynebacterium
d. Staphylococcus

A

Staphylococcus

is a genus of Gram-positive bacteria. Under the microscope, they appear round (cocci) and from in grape-like clusters.

46
Q

The IP receives a call from a young man who thinks he was exposed to HIV. He has just taken his first test (an enzyme-linked immunosorbent assay [ELISA]), which was negative. Which of the following is the most likely time frame after exposure in which HIV antibodies would be measurable in a blood test?

a. 6 months
b. 1 to 3 months
c. 12 months
d. 7 days

A

1 to 3 months

People usually develop measurable levels of HIV antibodies within 30 days of infection, though some may take longer - up to 3 months in some cases.

APIC chapter 81 HIV/AIDS

47
Q

The causative organism of Creutzfeldt-Jakob disease is a:

a. Helminth
b. Diphtheroid
c. Spirochete
d. Prion

A

Prion diseases

or transmissible spongiform encephalopathies (TSEs) are a family of rare progressive neurodegenerative disorders that affect both humans and animals.

APIC chapter 73 Creutzfeldt-Jakob disease and other Prion Diseases

48
Q

Anaerobic cultures should be used for any of the following sites EXCEPT:

a. blood
b. Transtracheal aspirate
c. Spinal fluid
d. Sputum

A

Sputum

An anaerobic bacteria culture is a method used to grow anaerobes from a clinical specimen. Anaerobes are commonly found on mucous membranes and other sites such as vagina and oral cavity. Therefore, specimens likely to be contaminated with these organisms should not be tested in this manner.

APIC chapter 24 Microbiology basics

49
Q

Routine microbiologic sampling is indicated for which of the following?

a. Respiratory therapy equipment
b. Dialysis fluid
c. Sterile disposable equipment
d. Operating room surfaces

A

Dialysis fluid

Microbiological environmental testing is not generally recommended.

APIC chapter 24 Microbiology Basics

50
Q

All of the following organisms can penetrate the intact epithelium of the conjunctiva or cornea except:

A. Staphylococcus aureus
B. Streptococcus pneumoniae
C. Neisseria meningitidis
D. Neisseria gonorrhoeae

A

Staphylococcus aureus

APIC Text, 4th edition, chapter 63 Ophthalmology Services.