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1

Which is most correct: A cell with a lightly stained nucleus:

a) has a cytoplasm with lots of free ribosomes
b) has little protein secretion
c) has an inactive genome
d) secretes large amounts of protein
e) has a heterochromatic nucleus

d) secretes large amounts of protein

2

A cell in G0 phase has what DNA content?

a) N
b) 2N
c) 3N
d) 4N
e) 1/2 N

b) 2N

3

In metaphase of mitosis, a cell has what DNA content?
a) N
b) 2N
c) 3N
d) 4N
e) 1/2 N

d) 4N

4

In what phase does a cell's DNA double?
a) G0
b) G2
c) G1
d) M
e) S

e) S

5

Which connection is CORRECTLY paired with it's function?

a) intermediate junction - stabilizes cytoskeletons
b) desmosome - attaches cell to basal lamina
c) gap junction - blocks passage of molecules and cells
d) tight junction - metabolic coupling
e) hemidesmosome - keeps neighboring cells from pulling apart

a) intermediate junction - stabilizes cytoskeleton

6

Which of the following structures is pathological in the epithelium?

a) microvilli
b) cilia
c) capillaries
d) mitotic figures
e) goblet cells

c) capillaries - epithelium is totally avascular.

7

What is not characteristic of a mucous cell?

a) flat nucleus
b) heterochromatic nucleus
c) rich with granules
d) poorly stained cytoplasm
e) light or empty appearing cytoplasm

c) rich with granules

8

What is not characteristic of a serous cell?

a) basophilic cytopolasm
b) lightly stained nucleus
c) rich with granules
d) round nucleus
e) heterochromatic nucleus

e) heterochromatic nucleus

9

What is a malignant tumor from skeletal muscle called?

rhabomyo- sarcoma

10

What is a malignant tumor from epithelial tissue called?

adenocarcinoma

11

What is a malignant tumor from cartilage called?

chondro- sarcoma

12

What is a malignant tumor from adipose called?

lipo- sarcoma

13

What is a benign tumor from cartilage called?

chondroma

14

What is a benign tumor from the parotid gland called?

adenoma

15

What is a malignant tumor from the epithelium of the GI tract called?

carcinoma

16

What is a malignant tumor from fibroblast connective tissue called?

fibro- sarcoma

17

What type of fiber in connective tissue is visible with a light microscope?

Type I collagen fibers

18

What type of fiber in connective tissue is visible with only special stains?

Reticular fibers = Type III collagen

19

What type of fiber is present in cartilage?

Type II Collagen

20

What type of fiber is visible only in basal lamina?

Type IV Collagen

21

Ostoclasts are drived from?

Monocytes

22

Plasma cells are derived from?

B-Lymphocytes

23

Lymphocytes are derived from?

Lymphoblasts

24

What is the function of:

1) Eosinophil?
2) Neutrophil?
3) Basophil?
4) Fibroblasts?
5) Lymphocyte?

1) Eosinophil :: parasite destruction
2) Neutrophil :: bacteria destruction
3) Basophil :: anaphylaxis
4) Fibroblasts :: secrete fibers and ground substance
5) Lymphocyte :: Production of antibodies

25

I have a bilobed nucleus and acidophilic grains, what is my function?? What am I?

parasite destruction (eosinophil)

26

I have a flat heterochromatic nucleus, what is my function?? What am I?

secrete fibers and ground substance (fibroblast)

27

I have a bilobed nucleus and dark staining cytoplasm, what is my function?? What am I?

secretion of histamine/heparine (basophil)

28

I have a multilobed nucleus with azurophilic granules, what is my function?? What am I?

destruction of bacteria (neutrophil)

29

I have a round nucleus with a thin basophilic cytoplasm, what is my function? What am I?

production of antibodies (lymphocyte)

30

Which type of cartilage has a perichondrium?

Hyaline cartilage and Elastic Cartilage

HE has all the perichondrium

31

Which type of cartilage has no perichondrium?

Fibrocartilage and Articular cartilage.

FAther does not like perichondrium.

32

What type of fibers are in compact bone?

Type I collagen (fibrocartilage)

33

What type of fibers are found in the Basal lamina?

Type IV collagen

34

What type of fibers are found in elastic cartilage?

Elastin

35

What type of fibers are round in connective tissue?

Type III collagen

36

What type of fibers are found in Bone Marrow?

Type III collagen

37

What type of fibers are found in hyaline cartilage and elastic cartilage?

Type II collagen

38

What is the difference between hyaline cartilage and elastic cartilage?

Elastic cartilage also has elastin fibers.

39

Which of the following is paired correctly?

a) osteoclasts - secrete osteoid
b) osteoblasts - reabsorb bone
c) osteocytes - interconnected by canaliculi
d) osteoprogenitor cells - trapped in lacunae
e) all of the above

c) osteocytes - interconnected by canaliculi

40

Which of the following is paired correctly?

a) osteoblasts- secrete osteoid
b) osteocytes - reabsorb bone
c) osteoprogenitor cells - interconnected by canaliculi
d) osteoclasts - trapped in lacunae
e) all of the above

a) osteoblasts- secrete osteoid

41

Which of the following is paired correctly?

a) osteoclasts - secrete osteoid
b) osteoblasts - reabsorb bone
c) osteoprogenitor cells - interconnected by canaliculi
d) osteocytes - trapped in lacunae
e) all of the above

d) osteocytes - trapped in lacunae

42

In endochondral ossification, what is responsible for interstitial growth (length)?

Chondrocyte division

43

In endochondral ossification, what is responsible for appositional growth (width)?

osteoblasts

44

In endochondral ossification, what is responsible for marrow cavity enlargement?

Osteoclasts

45

In intramembrane ossification, what is responsible for spicule and trabeculae growth?

Osteocytes

46

In intramembrane ossification, what is responsible for the connective tissue formation?

Fibroblasts

47

What is the difference between compact bone and spongy bone?

Compact bones have osteons (Haversion systems) and interstitial lamaellae

48

Which cells have both actin and myosin present?
a) smooth muscle
b) myofibroblasts
c) myoepithelial cells
d) pericytes

ALL OF THEM.

49

Which of the following cannot undergo mitosis?

a) lower motor neuron
b) purkinje fiber
c) astrocyte
d) sympathetic ganglion cell
e) preganglionic parasympathetic neuron

All but astrocyte.

a) lower motor neuron
b) purkinje fiber
d) sympathetic ganglion cell
e) preganglionic parasympathetic neuron

50

What type of nucleus does an eosinophil have?

Bilobed nucleus

51

What type of nucleus does a basophil have?

bilobed nucleus

52

What type of nucleus does a serous cell have?

Euchromatic round nucleus

53

What type of nucleus does a mature neutrophil have?

Segmented nucleus

54

What type of nucleus does a lymphocyte have?

Heterochromatic round nucleus

55

What type of nucleus does a monocyte have?

Large, bean shaped nucleus

56

Which of the following are found in hyalomeres?

a) lambda-granules
b) alpha granules
c) cytoskeletal elements
d) crystalline granules
e) no nucleus

c) cytoskeletal elements

57

Which of the following are found in granulomeres?

a) lambda-granules
b) alpha granules
c) cytoskeletal elements
d) crystalline granules
e) no nucleus

a) lambda-granules
b) alpha granules
d) crystalline granules

58

Which of the following are found in platelets?

a) lambda-granules
b) alpha granules
c) cytoskeletal elements
d) crystalline granules
e) no nucleus

e) no nucleus

59

Which of the following is most responsible for a hematooxylin stain?

a) lysosome
b) golgi appartus
c) hematochormatin
d) mitochondria
e) smooth endoplasmic reticulum

c) hematochormatin

60

What can hematoxylin stain?

nucleoli, hematochromatin, chromosomes, RER, Ribosomes

61

What does eosin stain?

lysosomes, mitochondria, and SER

62

What is the main function of cilia?

movement of material

63

What is the main function of microvilli?

increase surface area for absorption

64

I have a round, pykotic nucleus with acidophilic cytoplasm, what am I?

orthochromatic normoblast

65

I have a kidney shaped nucleus with orange granules in my cytoplasm, what am I?

Eosinophilic metamyleocyte

66

I have a round checkerboard nucleus with polychromatic cytoplasm, what am I?

Polychromatic erythroblast

67

I have no nucleus with some polyribosomes in my cytoplasm, what am I?

reticulocyte

68

I have a U-shaped nucleus with orange-red ribosomes in my cytoplasm, what am I?

Eosinophilic band

69

Which cells would you see in a blood smear?

a) neutrophilic band
b) eosinophil
c) basophil
d) reticulocyte
e) erythrocytes

ALL of them

70

Which of the following is secreted by the basal lamina?

a) heprain sulfate proteoglycan
b) Type IV collagen
c) enactin
d) laminin
e) all of the above

e) all of the above

All secreted by epithelial cells

71

Which of the following is attached to connective tissue via the basal lamina?

Schwann cell
Cardiac Muscle
Adipocyte
Serous Cell
Fibroblast

Schwann cell
Cardiac Muscle
Adipocyte
Serous Cell

72

What is a blood/bone marrow cancer called?

leukemia

73

What is an epithelial tumor called?

carcinoma

74

What is a benign gland tumor called?

adenoma

75

What is a malignant adipose cancer called?

sarcoma

76

What is a malignant tumor from a glandular or epithelial cell called?

adenocarcinoma

77

What are plasma cells derived from?

B-lymphocyes

78

What are myoblasts derived from?

satellite cells

79

What are histeocytes/macrophages derived from?

monocytes

80

What are osteocytes derived from?

Osteoblasts

81

What are chondroblasts derived from

Mesenchyme cells

82

At what stage does the embryo attach to the uterus?

a) solid ball of cells
b) fat disc with primative streak
c) flat dist w/ two cell layers
d) fluid filled ball of cells (blastocyst)
e) tubular shaped embryo with neural tube

d) fluid filled ball of cells (blastocyst)

83

Which of the following occurs first?

a) solid ball of cells
b) fat disc with primative streak
c) flat dist w/ two cell layers
d) fluid filled ball of cells (blastocyst)
e) tubular shaped embryo with neural tube

a) solid ball of cells (morula)

84

Which of the following occurs at the beginning of week three?

a) solid ball of cells
b) fat disc with primative streak
c) flat dist w/ two cell layers
d) fluid filled ball of cells (blastocyst)
e) tubular shaped embryo with neural tube

b) fat disc with primative streak

85

Which of the following occurs at the end of week three?

a) solid ball of cells
b) fat disc with primative streak
c) flat dist w/ two cell layers
d) fluid filled ball of cells (blastocyst)
e) tubular shaped embryo with neural tube

e) tubular shaped embryo with neural tube

86

Which of the following is an epiblast?

a) solid ball of cells
b) fat disc with primative streak
c) flat dist w/ two cell layers
d) fluid filled ball of cells (blastocyst)
e) tubular shaped embryo with neural tube

c) flat dist w/ two cell layers

87

Which of the following is an morula?

a) solid ball of cells
b) fat disc with primative streak
c) flat dist w/ two cell layers
d) fluid filled ball of cells (blastocyst)
e) tubular shaped embryo with neural tube

a) solid ball of cells

88

Which of the following does not arise from the mesoderm?

a) adrenal cortex
b) blood cells
c) support tissues
d) cerebellum
e) lymph cells

d) cerebellum

89

Which of the following is found in fibrocartilage?

a) cells interconnected with canaliculi
b) perichondrium
c) capillaries
d) isolated cells trapped in lacunae
e) fibroblasts in rows

d) isolated cells trapped in lacunae

90

Which of the following is found in bone?

a) cells interconnected with canaliculi
b) perichondrium
c) capillaries
d) isolated cells trapped in lacunae
e) fibroblasts in rows

a) cells interconnected with canaliculi

91

Which of the following is found in dense regular connective tissue?

a) cells interconnected with canaliculi
b) perichondrium
c) capillaries
d) isolated cells trapped in lacunae
e) fibroblasts in rows

e) fibroblasts in rows

92

What is not contribute to the formation of the cranial vault?

a) osteoblasts
b) osteoclasts
c) mesenchyme
d) chondrocyte
e) neural crest cells

d) chondrocyte

93

What structure is responsible for the unison of smooth muscle contractions?

gap junctions

94

Which of the following is not found on cardiac muscle?

a) abundant mitochondria
b) myofibrils
c) motor end plate
d) sarcomere
e) centrally located nuclei

c) motor end plate

95

Which of the following is secreted by the aorta?

a) elastic fibers
b) reticular fibers
c) collagen fibers
d) proteoglycans
e) all of the above

e) all of the above

96

Which of the following is not present in the ulnar nerve?

a) cell bodies
b) blood vessels
c) unmyelinated cells
d) epineurium
e) Schwann cells

a) cell bodies

97

What is the function of:

- neutrophils?
- basophils?
- eosinophils?
- lymphocytes?
- monocytes?

- neutrophils :: kill bacteria
- basophils :: anaphylaxis
- eosinophils :: allergic reaction/destruction of parasites
- lymphocytes :: secretion of antibodies
- monocytes :: phagocytosis

98

Platelets secrete:

a) thromboplastin
b) histaminase
c) meloperoxidase
d) major basic protein
e) eosinophilic hemotactic

thromboplastin

99

neutrophils secrete:

a) thromboplastin
b) histaminase
c) meloperoxidase
d) major basic protein
e) eosinophilic hemotactic

meloperoxidase

100

basophils secrete:

a) thromboplastin
b) histaminase
c) meloperoxidase
d) major basic protein
e) eosinophilic hemotactic

eosinophilic hemotactic

101

eosinophils secrete:

a) thromboplastin
c) meloperoxidase and histimase
d) major basic protein
e) eosinophilic hemotactic

meloperoxidase and histaimase

102

Where does hematopoesis occur in the embryo?

bone marrow, yolk sac, liver, thymus, spleen and lymph nodes

103

Where does hematopoesis occur after birth?

mostly in the bone marrow but also in lymphoid organs

104

What are characteristics of necrotic cells?

shrunken nucleus, swollen ER, enlarged cell volume, very acidophilic cytoplasm

105

What is the function of a zona occludens (tight junction)?

Prevent diffusion between cells

106

What is the function of intermediate junctions (zona adherens)?

anchors filaments to terminal web

107

What is the function of desmosomes (macula adherens)?

strong spot attachment between cells

108

What is the function of hemidesmosomes?

attaches the cell to the basal lamina

109

What is the function of the gap junction?

Allows passage of small molecules directly from one cell to another

110

The replacement of one cell with another is called...?

metaplasia

111

The alteration of size, shape and organization of cells is called...?

dysplasia

112

The increase in cell numbers is called...?

hyperplasia

113

The increase in cell size and organelles is called?

hypertrophy

114

The reversal of differentiation of cells is called...?

anaplasia

115

Which is correctly paired?

a) smooth muscle - round nucleus
b) adipose cell - flat nucleus
c) osteoblast - cigar shaped nucleus
d) plasma cell - kidney shaped nucleus
e) mast cell - bilobed

b) adipose cell - flat nucleus

116

Which is correctly paired?

a) smooth muscle - kidney shaped nucleus
b) adipose cell - round nucleus
c) osteoblast - round euchromatic nucleus
d) plasma cell - cigar shaped nucleus
e) mast cell - bilobed

c) osteoblast - round euchromatic nucleus

117

Which is correctly paired?

a) smooth muscle - kidney shaped nucleus
b) adipose cell - round nucleus
c) osteoblast - bilobed
d) plasma cell - cigar shaped nucleus
e) mast cell - small round nucleus

e) mast cell - small round nucleus

118

Which is correctly paired?

a) smooth muscle - central nucleus
b) adipose cell - round nucleus
c) osteoblast - bilobed
d) plasma cell - cigar shaped nucleus
e) mast cell - kidney shaped nucleus

a) smooth muscle - central nucleus

119

Which is correctly paired?

a) smooth muscle - bilobed
b) adipose cell - central nucleus
c) osteoblast - cigar shaped nucleus
d) plasma cell - round nucleus
e) mast cell - kidney shaped nucleus

d) plasma cell - round nucleus

120

Answer True or False. If false, give the correct description:

Eosinophils:
a) are agranulocytes
b) divided into hyalomere and granulomere
c) have nucleus with many lobes
d) contains granules with crystalline cores
e) are primarily active in the blood stream

a) are agranulocytes - FALSE. Eosinophils are granulocytes

b) divided into hyalmere and granulomere - FALSE. Platealets are divided into hyalomere and ganulomere

c) have nucleus with many lobes. - FALSE. Eosinophils have only two lobes. Neutrophils have many lobes

d) contains granules with crystalline cores - TRUE

e) are primarily active in the blood stream - False, also active in connective tissue.

121

Which of the following would not be present in a blood smear?

a) reticulocyte
b) plasma cell
c) monocyte
d) polymorphonuclear leukocyte
e) thrombocyte

b) plasma cell

122

What in a basophilic erythroblast makes it blue?

polyribosomes

123

Which vessel has longitudinally arranged muscle in tunica adventia?

Large Vein

124

Which vessel has the tunica adventia as the thickest layer with a loose periphery?

Small/median vein

125

Which vessel has a thick layer of elastic fenestrated sheets in tunica media with a little smooth muscle?

Elastic artery

126

Which vessel has a prominent internal elastic membrane?

muscular artery

127

Which vessel has a thick concentric layer of smooth muscles with elastic sheaths?

muscular artery

128

The vena cava is what type of vessel, which is characterized by what?

A large vein with longitudinally arranged muscle in tunica adventia

129

The femoral vein is what type of vessel, which is characterized by what?

small/median vein with tunica adventia as the thickest layer with a loose periphery

130

The ascending aorta is what type of vessel, which is characterized by what?

elastic artery; which has a thick layer of elastic fenestrated sheets in tunica media with a little smooth muscle

131

The femoral artery and brachial artery are what type of vessels, which is characterized by what?

Muscular arteries; which have a prominent internal elastic membrane and thick concentric layer of smooth muscles with elastic sheaths

132

Which of the following is an example of a pseudounipolar nerve?

a) parasympathetic ganglion
b) preganglionic sympathetcic
c) lower motor neuron
d) dorsal root ganglion

d) dorsal root ganglion

133

Which of the following is not a multipolar nerve?
.
a) parasympathetic ganglion
b) preganglionic sympathetcic
c) lower motor neuron
d) dorsal root ganglion

d) dorsal root ganglion