Pre Midterm Flashcards
Bacteria associated with an increased rick for atherosclerosis.
Chlamydia pneumoniae
Mycoplasma pneumoniae is associated with autoimmune hemolytic anemia secondary to cold agglutinins
The only gram+ bacteria that produces endotoxin.
Listeria monocytogenes
A 7 year old girl suffered a sore throat. Consult was done with a private physician and was prescribed with unrecalled antibiotics that offered relief. 3 weeks later she developed a new onset murmur heard best at the apex. She also had pain on her ankles and knees relieved by aspirin. What are the characteristics of the most likely causative organism?
A. gram positive, anaerobic, motile, tennis racket shaped rods
B. gram positive, aerobic, club shaped rods
C. gram positive, catalase negative, bacitracin sensitive, PYR test positive cocci in chains
D. gram positive, catalase positive, coagulase positive cocci in clusters

E. Gram positive, catalase negative, bacitracin sensitive, PYR test positive cocci in chains–Strep pyogenes
Clostridium tetani: gram +, anaerobic, motile, tennis racket shaped rods
Cornyebacterium diptheriae: gram +, non-sporeforming, club shaped rods
Staph. Aureus- gram +, catalase positive, coagulase positive cocci in clusters
Strep. Pneumoniae- gram +, catalase negative, optochin sensitive, bile soluble, quellung reaction positive cocci in chains
Cytomegalic inclusion disease of newborns is characterized by involvement of what organ systems?
CNS
Reticuloendothelial system
CMV inclusion disease of newborns is characterized by involvement of the CNS, and RES
Clinical features: IUGR ,jaundice, hepatosplenomegaly, microcephaly, thrombocytopenia, and retinitis.
Mario developed headache, malaise, fever, fatigue and sore throat. Pe noted enlarged LN and splenomegaly. Biopsy noted downey cells. What is the morphology of organism?
A. single stranded DNA virus, naked, icosahedral, linear
B. single stranded RNA virus, negative sense, enveloped,
C. Single stranded RNA virus, bullet shaped
D. Double stranded DNA virus, enveloped, icosahedral, linear virus
E. Single stranded RNA virus, positive sense, naked, icosahedral.
D. Double stranded DNA virus, enveloped, icosahedral, linear virus — EBV
Parvovirus: ssDNA virus, naked, icosahedral, linear.
Measles: sssRNA virus, negative sense, enveloped, helical.
Rhabdo: ssRNA virus, bullet shaped;
Norwalk: ssRNA virus, positive sense, naked, icosahedral.
HBsAg (-), Anti HBS (-), HbEAg (-), Anti Hbc IgM (+)
A. Chronic infetion
B. Window period
C. Acute infection
D. Acquired antibody through immunization
E. Not enough data to interpret
Window period
Outer envelope glycoprotein of the HIV virion. A. gp 41 B. gp120 C. CCR5 D. CXCR4 E. P24  
gp120
CCR5, the receptor for chemokines RANTES;
MIP-1a, and MIP-1b: is the predominant coreceptor for macrophage tropic strains of HIV-1;
CXCR4: the receptor for chemokine SDF-1, is the coreceptor for lymphocyte tropic strains of HIV-1.
gp41: transmembrane envelope glycoprotein.
p24: nucleocapsid core proetein of virion.
Mario complains of multiple hypopigmented patches on his trunk and back. Consult was done and was requested biopsy of the skin lesion which revealed 'Spaghetti and meatballs' upon KOH smear. What is the likely causative organism? A. Candida spp B. Blastomyces Dermatitides C. Aspergillus fumigatus D. Malasezzia furfur E. Rhizopus
Malasezzia furfur
Candida- pseudohyphae on KOH;
Blastomyces Dermatitides- broad based budding yeast;
Aspergillus Fumigatus- acute angle branching hyphae;
Rhizopus- right angle branching hyphae
What is otherwise called the human threadworm? A. Trichuris Trichura B. Toxoplasma Gondii C. Strongyloides Stercoralis D. Ascaris lumbricoides E. Enterobius Vermicularis
Strongyloides stercoralis
Trichuris Trichura- whipworm;
Enterobius Vermicularis- seatworm, pinworm;
Enterobius Vermicularis- giant roundworm.
Causative agent of debilitating illness causing hanging groin, river blindness, and lizard skin.
Onchocerca volvulus
DOC: Ivermectin
Most common cause of parasitic meningitis.
Angiostrongylus cantonensis
It is transmitted via undercooked seafood. Causes eosinophilic meningitis, most common cause of parasitic meningitis.
Malignant tertian malaria
Plasmodium falciparum
P. Malariae-benign quartan;
P Ovale and Vivax- benign tertian.
A negative ‘skin test’ or anergy after a tuberculin skin test,despite a positive TB infection can be negative if a person has one/more of the following conditions?
A. Overwhelming tuberculosis B. Sarcoidosis
C. Hodgkin’s disease
D. Both A and B
E. All of the above
E. All of the above
The following conditions can result to a negative PPD, with TB infection: 1. Sarcoidosis, 2. Overwhelming tuberculosis, measles, hodgkins disease, AIDS, immunosuppresion.
Streptococcus pyogenes is a virulent bacteria that causes a wide spectrum of diseases. What bacterial enzyme activates plasminogen? A. Hyaluronidase B. Streptokinase C. DNase D. C5a peptidase E. Lyase
B. Streptokinase
Streptokinase of fibrinolysin activates plasminogen.
Hyaluronidase: degrades hyaluronic acid( aka spreading factor)
Dnase degrades DNA in exudates or necrotic tissue
The following viruses belong to the Paramyxoviridae family, except? A. Measles Virus B. Mumps Virus C. Respiratory Syncytial Virus D. Parainfluenza Virus E. Parvovirus
except: E. Parvovirus
Measles, Mumps, RSV and Parainfluenza (MeMuRP) Virus are the viruses that belong to the Paramyxoviridae family.
