Predictions Flashcards
(76 cards)
What is schizophrenia?
A mental disorder characterised by disruption of cognition and emotion.
How does schizophrenia manifest?
It manifests through a person’s sense of self, actions, thoughts, perceptions and language.
What are the clinical characteristics of schizophrenia?
2 or more of the following: Delusions (faulty perceptions), Hallucinations (interpretting things incorrectly), Grossly disorganised/catatonic behaviour, Negative symptoms (e.g avolition).
Areas of functioning must be substandard
Continuous signs of disturbance must persist for at least 6 months.
How many symptoms are needed for a diagnosis if delusions are bizarre?
Only one symptom is needed if delusions are bizarre, or hallucinations consist of running commentary or conversations.
What are positive symptoms in schizophrenia?
Positive symptoms add to or distort normal functions.
What are negative symptoms in schizophrenia?
Negative symptoms take away or indicate a loss of normal functioning.
SZs with mainly negative symptoms respond much less to drug therapy
What are hallucinations
Sensory malfunction, meaning you perceive the environment incorrectly.
Usually hearing voices, but can also include seeing things, smelling, or feeling things that aren’t there.
What are delusions?
Faulty beliefs, rather than perceptions.
-e.g paranoid delusions (fear of being watched, persecution etc)
- delusions of grandeur; inflated self-importance
- delusions of reference; believing secret messages meant for just them
What is disorganised speech?
Abnormal thought processes lead to disorganised thoughts, which in turn affect speech.
What is grossly disorganised/catatonic behaviour?
Inability to start or complete a task due to lack of focus or motivation.
Catatonic is reduced response to immediate environment or aimless repeated motor activity
What is speech poverty (Alogia)?
Slowed/blocked thoughts lead to lessened speech fluency and productivity.
What is avolition?
Less interest/desire for things; inability to begin any meaningful behaviour.
What is validity in the context of schizophrenia?
Whether or not the classification or diagnosis of schizophrenia is accurate and correct.
What is comorbidity?
Two or more conditions/disorders can occur simultaneously within a patient.
What did Buckley suggest about comorbidity in schizophrenia?
-suggested that depression occurs in around 50% of SZ patients + substance abuse in around 47%
-This is an issue since diagnosis and treatment is harder; some symptoms of SZ may be depression and separate from SZ,
-may require contrasting treatments.
-hard to advise patients
Comorbidity AO3
✔ Suicide rates
SZ patients risk a 1% chance of committing suicide
rises to 40% if depression is co-morbid with 10% succeeding
Therefore demonstrates that there is a risk to life if disorders are not identified and treated in time
✔Weber
found correlations between SZ and physical comorbid conditions such as diabetes, asthma etc
Supports concern that SZs have issues with self care or they receieve a lower standard of medical care
Therefore comorbidity is serious issue in diagnosing SZ.
What is symtom overlap?
when two disorders have a symptom in common
-valid diagnosis must show an illness to be distinct from other disorders (external) and be based on a system which measures what it claims to (internal)
What did Swets et al find about schizophrenia and OCD?
-12% of tested SZ patients also fulfilled criteria for OCD
-25% displayed significant OCD symptoms
-this is despite the prevalence of SZ in society being 1 in 1000, and OCD being 2-3%
Ellason and Ross
-Pointed out that patients suffering Dissociative Identity Disorder have more SZ symptoms that SZ patients
therefore validity of DSM and ICD must be questioned as they do not successfully classify SZ as separate from other disorders
This is an issue because in order to treat a disorder effectively, we must be able to identify it
Gender Bias A03
Lording and Powell
randomly selected male and female psychiatrists and gave them vignettes of patients
found higher diagnosis rates when the patient was believed to be male
also made assumptions on the gender neutral vignettes that patient was male
no significant gender bias found amongst female psychiatrists
Therefore suggests that diagnosis is influence by not only by the gender of the patient but also the gender of the clinician
What is the dopamine hypothesis?
Too much dopamine in certain areas of the brain causes positive symptoms of schizophrenia.
SZs may have abnormally high Dz receptors resulting in more dopamine binding and therefore more neurons firing
Dopamine Agonist Drugs
e.g Amphetamine
-stimulates nerve cells containing dopamine, causing synapse to be flooded with this neurotransmitter
-non schizophrenic individuals exposed to a dopamine agonist can develop hallucinations and delusions like of a SZ episode
Grilly
found that ppl with Parkinson (low dopamine) who took dopamine agonists have been found to develop SZ symptoms
Dopamine antagonists
antipsychotic drugs that block the activity of dopamine in the brain
-reduces activity in the neural pathways of the brain that use dopamine
-these drugs eliminate symptoms such as hallucinations and dopamine
The fact that these drugs alleviated many of the SZ symptoms strengthens the importance of the role of dopamine