PREP Flashcards
(26 cards)
what are the red complex bacteria
p gingivalis
t forsythia
t denticola
what is the food source for p gingivalis
iron
what percent of patients have p gingivalis in their biofilm?
85%
what two characteristics do p gingivalis have
lipopolysaccharide
gram negative
what does lps release
endotoxins
what is a result of the release of endotoxins by lps
septic shock, skin lesions, high fever
what is PPAD
peptidylarginine deiminase
what is the bacteria that releases ppad
p gingivalis
when there is HIGH RANKL and LOW OPG;
increase in osteoclasts
(bone resorption)
when there is LOW RANKL and HIGH OPG
decrease in osteoclasts
(no bone resorption)
what kind of diseases are contagious
communicable diseases
when can communicable diseases be transferred
any phase
what are the 5 mechanisms of action
inhibit cell wall synthesis
inhibit protein synthesis
inhibit metabolic activity
inhibit nucleic acid synthesis
alter cell membrane
what is the mnemonic for the stages of viral replication
A PURple Apple Might Redden
list the stages of virus replication
attachment
penetration
uncoating
replication
assembly
maturation
release
(stage of virus replication)
binding to the host cell using specific receptor molecules in the plasma membrane
attachment
(stage of virus replication)
requires energy by the host cell
endocyosis or phagocytosis
penetration
(stage of virus replication)
breakdown of the capsid and release of genome into the cell to be replicated/transcribed
uncoating
(stage of virus replication)
proteins that will be incorporated into the virion are made through expression of viral genes
genome is copied
replication
(stage of virus replication)
newly created components collect at a site and form an immature virus particle
assembly
(stage of virus replication)
changes that result in infectious virus particles
capsid changes are often involved
maturation
(stage of virus replication)
release of virion into extracellular environment
release
pro of broad spectrum antibiotic
not specific
con of broad spectrum antibiotic
can hurt oral microflora