Prevention/Anticipatory Guidance Flashcards
(102 cards)
Definition of anticipatory guidance
To provide developmentally relevant information about a child’s health to help prepare parents for milestones in the future
Definition of dental caries
Chemical dissolution of tooth surface caused by metabolic events in the biofilm covering the affected area
Contributing factors to caries
Oral hygiene Diet Microbiology Fluoride Genetics (immune, enamel, saliva) Environmental factors
Keyes Triad
Host and teeth
Microflora
Substrate (diet)
Very simplistic approach
Koch’s Postulates
Describes requirements for a microorganisms to be considered in an etiologic agent for disease
Found in all cases of disease
Organism should be grown on artificial media for several subcultures
Pure subculture should produce disease in susceptible animal
Not able to be done in caries
-many confounders (behavior, education, SES, genetics, etc.)
Specific Plaque Hypothesis
Only certain species of bacteria are involved in caries process
Nonspecific Plaque Hypothesis
All plaque/bacteria are pathogenic
Ecological Plaque Hypothesis
Shifts in pH of biofilm cause a shift toward cariogenic bacteria (S mutans) in the balance of resident oral flora, resulting in dsease
Extended Caries Ecological Hypothesis
Dental plaque as a dynamic microbial ecosystem in which non-mutans bacteria are key players for maintaining dynamic stability
Low pH environments can stimulate non-mutans bacteria to be more acidogenic
Variety of bacteria that are acid-producing, not just S mutans
Given the right environment, even the good bacteria can cause demineralization and destruction of tooth surface
Composition of enamel
95% hydroxyapatite
- 5% water
- 5% organic matrix
Calcium phosphate crystals make up 99% of dry weight
Active vs inactive carious lesion
Active lesions: white, opaque, rough
Inactive lesions: smooth, hard
White Spot Lesion
Intact surface zone: 20-50um
Body of lesion - pore volume > 5%
Dark zone - pore volume 2-5%
Translucent zone - advancing front of lesion
Dentin reaction to caries
Vital tissue that reacts to external insults
Most common reaction to caries progression is tubular sclerosis and occlusion of dentin
Pulp-dentin reactions
Histologically early signs of tubular sclerosis can be seen before the enamel lesion reaches the DEJ
Dentin demineralization does not extend laterally beyond contact area with enamel lesion
Reactionary dentin may form before dentin is invaded by bacteria
Biofilm
Necessary but not sufficient to cause disease
Microbial biofilm on teeth is prerequisite of caries lesions
Primary route of transmission of caries
Saliva
Vertical transmission from mother
Early colonizers of bacteria
S. Mitis
S. Salivarius
S. Oralis
Prior to tooth eruption, these bacteria are transient, usually on gingival tissues
Acquired pellicle formation
Acellular, proteinaceous film that forms on teeth within minutes after cleaning
Composed of salivary glycoproteins, phosphoproteins, lipids and components from gingival crevicular fluid
1 micron thick
Critical role in bacterial colonization
Facilitates remineralization by maintaining calcium and phosphate
Microbial succession
Early bacteria create environment either favorable to others or unfavorable to themselves
Gradual replacement with other species who are better suited to modified environment
Microbial hemostasis is a state of equilibrium between microflora and local environment
Disruption can result in disease
Characteristics of cariogenic bacteria
Rapid transport and conversion of sugars to acid
Ability to maintain metabolism under extreme conditions like low pH
Production of extracellular polysaccharides such as glucans that shift to acidic
Acid producing cocci and rods
SECC bacteria
More anaerobic cultures found
S sanguinis generates alkali from arginine and decreases cariogenicity of acidogenic bacteria
Window of Infectivity
Between 19-31 months of age
Window appears to close after all primary teeth erupt
Once stable plaque or biofilm covers tooth surface, MS is less likely to be established
2nd window of infectivity at 6 years when 1st molars erupt
Transmission of caries
Vertical: parent to child (most often from mother)
Horizontal: spouses
Factors affecting acquisition of MS
Erupted teeth
Presence of hypoplasia
Diet high in fermentable carbohydrates
Antibiotic intake (?) - conflicting results