PSA Flashcards

1
Q

common side effect of Lymecycline

A

photosensitivity

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2
Q

medication to induce a withdrawal bleed in PCOS

A

medroxyprogesterone, 10, mg, oral, once a day

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3
Q

prescription for iron deficiency anaemia

A

ferrous sulfate, 200, mg, oral, once a day

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4
Q

Management of paraccetamol OD in pt with level >150/kg

A

Admit and commence N-Acetylcysteine 150 mg/kg IV over 1
hour immediately followed by 50 mg/kg IV over 4 hours, then 100 mg/kg IV over
16 hours.

Activated charcoal given only if ingested <1hr ago

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5
Q

what kind of laxatives should be used in a patient with haemorrhoids

A

Bulk forming laxatives

eg.
Methylcellulose, 1, g, oral, three times a day

Sterculia, 2, sachet(s), oral, once a day

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6
Q

Types of laxatives and when to give them

A
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7
Q

Anticoag given for suspected PE

A

rivaroxiban or apixiban

offer apixaban or rivaroxaban first line, and if
these are not suitable, low molecular weight heparin (LMWH) for at least 5 days followed by dabigatran or edoxaban, or
LMWH concurrently with a vitamin K antagonist for at least 5 days”. LMWH is always the anti-coagulant of choice in patients
who also have cancer.

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8
Q

Post op anticoag

A

Aspirin, 75mg, mg, oral, once a day

Enoxaparin, 40, mg, subcutaneous, once a day

Dalteparin, 5000, units, subcutaneous, once a day

Rivaroxaban, 10, mg, oral, once a day

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9
Q

Causes of gingival hyperplasia

A

phenytoin, ciclosporin, calcium channel blockers and AML

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10
Q

CYP450 enzyme inducers

A

(crap GPs)
Carbemazepine
Rifampicin, ritonavir
Alcohol (chronic)
Phenytoin
Griseofulvin
Phenobarbitol
St johns wort, smoking, sulphonyureas

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11
Q

CYP450 enzyme inhibitors

A

(sickfaces.com)
Sodium valporate
Isoniazid
Ciprofloxacin
Ketoconazole
Fluconazole
Alcohol (binge drinking)
Cimetidine
Erthyromycin
Sulfonamides
Chloramphenicol
Omeprazole
Metronidazole

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12
Q

when should warfarin be stopped before elective surgery?

A

5 days before
checlk INR night before

high risk of VTE pt may require bridging with LMWH and stopped 24hrs before surgery

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13
Q

pts on warfarin requiring emergency surgery

A

give IV vitamin K and try do delay surgery for 6-12 hrs if possible

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14
Q

medical reasons for needing VTE prophylaxis

A

Significant reduction in mobility for 3 days or more (or anticipated to have significantly reduced mobility)
active cancer/chemotherapy
Aged over 60
Known blood clotting disorder (e.g. thrombophilia)
BMI over 35
Dehydration
One or more significant medical comorbidities (e.g. heart disease; metabolic/endocrine pathologies; respiratory disease; acute infectious disease and inflammatory conditions)
Use of hormone replacement therapy (HRT)
Use of the combined oral contraceptive pill
Varicose veins
Pregnant or less than 6 weeks post-partum

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15
Q

surgical reasons for needing VTE prophylaxis

A

Hip/knee replacement
Hip fracture
General anaesthetic and a surgical duration of over 90 minutes
Surgery of the pelvis or lower limb with a general anaesthetic and a surgical duration of over 60 minutes
Acute surgical admission with an inflammatory/intra-abdominal condition
Surgery with a significant reduction in mobility
Critical care admission

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16
Q

options for VTE prophylaxis

A

TED stockings

fondaparinaux sodium
LMWH eg. enoxoparin
unfractionated heparin

17
Q

drugs that should be reviewed in an elderly pt with confusion

A

opioids
Benzodiazepines
cyclizine
check Na

18
Q

what drug should be stopped if a patient is started on clarithromycin

A

statins

as clari is an inhibitor therefor increases does of statin and increases risk of SEs

19
Q

what is the correct way to measure tacrolimus levels?

A

trough level before the morning or evening dose

20
Q

inducing withdrawal bleed in PCOS

A

methylprogesterone acetate 10mg PO OD

21
Q

what should be monitored to look for beneficial results of furosemide in acute HF?

A

daily weights

22
Q

what drug can causes cholestatic jaundice

A

flucloxacillin

23
Q

drugs to be with held in AKI

A

Diuretics
ACEi
Metformin
NSAIDs

+ allopurinol

nitrofurantoin avoided if eGFR low

24
Q

what should be done to monitor beneficial response to ACEi in HF Mx

A

exercise tolerance
LV function

25
Q

what are the most serious adverse effects of ciclosporin

A

nephrotoxicity and HPTN

26
Q

which diabetic drug is CI in HF and why

A

thiazolidinediones

can cause fluid retention

27
Q

which drugs are usually given once weekly

A

methotrexate
bisphosphonates

28
Q
A