PSA 2 Flashcards

(24 cards)

1
Q

Why is “insulin 10 units IV stat” a prescribing error?

A

Insulin should always specify the type (e.g., actrapid) to avoid confusion and errors.

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2
Q

Why is prescribing “co-amoxiclav for a penicillin-allergic patient” an error?

A

Co-amoxiclav contains amoxicillin, which can cause a severe allergic reaction in penicillin-allergic patients

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3
Q

Why is “amlodipine 20 mg daily” inappropriate?

A

The maximum dose of amlodipine is 10 mg daily. Higher doses increase the risk of side effects such as peripheral edema.

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4
Q

What monitoring is required for clozapine?

A

FBC (weekly for the first 18 weeks, then less frequently) to monitor for agranulocytosis. Monitor also for weight, lipids, and glucose.

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5
Q

What needs monitoring in a patient taking ciclosporin?

A

Renal function, blood pressure, and serum ciclosporin levels (narrow therapeutic index).

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6
Q

What do you monitor for a patient on rifampicin?

A

LFTs (risk of hepatotoxicity) and interactions with other drugs (strong inducer of cytochrome P450).

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7
Q

What is the first-line treatment for hospital-acquired pneumonia?

A

Piperacillin-tazobactam 4.5 g IV three times daily.

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8
Q

What antibiotic is used for Lyme disease in an adult?

A

Doxycycline 100 mg PO twice daily for 14-21 days.

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9
Q

What is the preferred treatment for chlamydia in pregnancy?

A

Azithromycin 1 g PO as a single dose

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10
Q

What is the potassium concentration in Hartmann’s solution?

A

5 mmol/L.

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11
Q

When is 5% dextrose used as a maintenance fluid?

A

For patients with no significant electrolyte losses or hypernatremia.

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12
Q

What are the risks of prescribing trimethoprim in pregnancy?

A

Trimethoprim is teratogenic in the first trimester due to folate antagonism.

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13
Q

What is the main side effect of bisphosphonates?

A

Esophagitis (ensure patients take them with water and remain upright for 30 minutes).

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14
Q

What are signs of serotonin syndrome?

A

Agitation, hyperreflexia, clonus, tremor, and hyperthermia.

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15
Q

What is the maximum dose of diclofenac in a day?

A

150 mg (50 mg three times daily).

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16
Q

How is naloxone dosed for respiratory depression in opioid overdose?

A

Start with 400 micrograms IV, repeat every 2-3 minutes as needed (max 10 mg).

17
Q

What is the recommended starting dose of gabapentin for neuropathic pain?

A

300 mg PO once daily, titrating up to 300 mg three times daily.

18
Q

What is the preferred anticoagulant in patients with eGFR <15 mL/min?

A

Unfractionated heparin (dose-adjusted by APTT).

19
Q

How do you adjust levothyroxine in patients with ischemic heart disease?

A

Start at a low dose (e.g., 25 mcg/day) and titrate slowly.

20
Q

What antihypertensives are safe in breastfeeding?

A

Labetalol, nifedipine, enalapril, or captopril.

21
Q

Write a PRN prescription for metoclopramide for nausea.

A

Metoclopramide 10 mg PO/IV every 8 hours PRN for nausea (max 30 mg/day). - PO nausea, IV vomiting

22
Q

What is the maximum dose of senna in 24 hours?

A

30 mg (usually taken at bedtime).

23
Q

What is the treatment for acute adrenal crisis?

A

IV hydrocortisone 100 mg stat, followed by 50 mg every 6 hours, and IV fluids.

24
Q

What is the first-line treatment for status epilepticus?

A

IV lorazepam 4 mg, repeated after 10 minutes if seizures persist.