Psoriatic Arthritis Flashcards

(28 cards)

1
Q

Define psoriatic arthritis

A

Chronic inflammatory arthritis affecting the joints and connective tissue associated with psoriasis

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2
Q

Psoriatic arthritis is part of which group of conditions

A

Seronegative spondyloarthropathy

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3
Q

The psoriatic arthritis varies in severity.

How do they present

A

Patients may have a mild stiffening and soreness in the joint or it can be completely destroyed

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4
Q

Name the three conditions that are classified as seronegative spondyloarthropathy

A

Psoriatic arthritis

Reactive arthritis

Ankylosing spondylitis

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5
Q

Psoriatic arthritis does not have a single pattern of affected joints.

Name the 5 recognised patterns

A

“SADAS”

S - Symmetrical polyarthritis

A - Asymmetrical oligoarthritis

D - Distal interphalangeal joint arthritis

A - Arthritis mutilans

S - Spondylitis with sacroiliac and spinal involvement

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6
Q

What are the two most common recognised patterns for psoriatic arthritis

A

Symmetrical polyarthritis

Asymmetrical oligoarthritis

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7
Q

Describe symmetrical polyarthirits - recognised pattern for psoriatic arthritis

A

Inflammation > 5 joints in a symmetrical fashion

Similar presentation to rheumatoid arthritis

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8
Q

Which recognised pattern of psoriatic arthritis is more common in women

A

Symmetrical polyarthritis

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9
Q

Which recognised pattern of psoriatic arthritis is more common in men

A

Spondylitis with sacroiliac and spinal involvement

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10
Q

What joints are commonly affected in symmetrical polyarthritis (a recognised pattern of psoriatic arthritis)

A

Hands, wrists, ankles and DIP joints are affected

MCP joints are less commonly affected (unlike rheumatoid)

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11
Q

Describe asymmetrical oligoarthritis (recognised pattern of psoriatic arthritis)

A

Inflammation < 5 joints

Asymmetrical distribution of joint involvement

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12
Q

Describe distal interphalangeal joint arthritis (recognised pattern of psoriatic arthritis)

A

Characterised by distal interphalangeal (DIP) joint involvement

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13
Q

What is the name given to the most severe pattern of psoriatic arthritis

A

Arthritis mutilans

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14
Q

Describe arthritis mutilans (recognised pattern of psoriatic arthritis)

A

Severe deformity where there is destruction (osteolysis) of bone and collapse of digits

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15
Q

Describe spondylitis with sacroiliac and spinal involvement (recognised pattern of psoriatic arthritis)

A

Inflammation of the joints in the spine and atlanto-axial joint involvement

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16
Q

What are the two major risk factors for psoriatic arthritis

A
  • Family history or personal history of psoriasis or psoriatic arthritis
  • Gender
    • Symmetrical polyarthritis is more common in females
    • Spondylitis is more common in males
17
Q

Name some of the clinical features of psoriatic arthritis

A
  • Presence of psoriasis
  • Prolonged morning stiffness in joints (lasting > 30 mins)
  • Joint or digit swelling
  • Pitting of the nails
  • Onycholysis – separation of the nail from the bed
  • Dactylitis – uniform swelling of an entire digit. Seen as soft tissue swelling on x-ray
  • Enthesitis – inflammation of the entheses, which are the points of insertion of tendons into bone
18
Q

Dactylitis is a unique feature of which arthritis

A

Psoriatic arthritis

19
Q

Define enthesitis

A

Clinical feature of psoriatic arthritis

Inflammation of the entheses, which are the points of insertion of tendons into bone

20
Q

How is psoriatic arthritis diagnosed

A

Clinical diagnosis based on history and physical examination

21
Q

What two components uniquely distinguishes psoriatic arthritis from rheumatoid arthritis.

A

The presence of DIP joint involvement

Dactylitis (uniform swelling of an entire digit)

22
Q

Define Dactylitis

A

Uniform swelling of an entire digit

Seen as soft tissue swelling on x-ray

23
Q

What is the result of ESR and CPR in psoriatic arthritis

A

Will be normal

24
Q

What are the x-ray features of psoriatic arthritis

A

Does not have a single pattern of affected joints – several recognised patterns

Erosion in the distal interphalangeal (DIP) joint

Periarticular new bone formation

Osteolysis – destruction of bone

Pencil-in-cup appearance – central erosions of the bone beside the joints (see image)

Dactylitis – uniform swelling of an entire digit. Seen as soft tissue swelling on x-ray

25
Pencil-in-cup appearance is an unique x-ray pattern in which arthritis
Psoriatic arthritis
26
Pencil-in-cup appearance is a x-ray pattern of psoriatic arthritis. Describe this pattern
Central erosions of the bone beside the joints (see image)
27
How is psoriatic arthritis managed
NSAIDs e.g. ibuprofen, naproxen, diclofenac Physiotherapy Disease Modifying Antirheumatic Drugs (DMARDs) e.g. methotrexate Intra-articular corticosteroid injection
28
What is the 2nd line therapy for managing psoriatic arthritis (if NSAIDS dont work)
Anti-TNF medications e.g. etanercept, infliximab or adalimumab