Psych- Tx Flashcards

(51 cards)

1
Q

Bipolar gold standard tx
and second line

A

Lithium- monitoring required can fuck kidneys and cause hyperparathyroidisn

sodium valproate second line

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2
Q

management of mania/hypomania in bipolar

A

consider stopping antidepressant if the patient takes one; antipsychotic therapy e.g. olanzapine or haloperidol

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3
Q

management of depression in bipolar

A

talking therapies; fluoxetine is the antidepressant of choice

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4
Q

Ed tx

A

Halt weight loss, if weight gain required then aim for 0.5-1.0kg inc per week

Medical stabilisation etc.

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5
Q

Schizophrenia tx guidelines

A

1st line: 2nd generation (atypical) 6-8 weeks + cbt

2: 1/2nd generation 6-8 weeks

3: check diagnosis, consider psychological input, optimise social support, check compliance

monitor CVD risks

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6
Q

First time pharmacological treatment for depression
how long should it be prescribed minimum

A

SSRIs- fluoxetine

at least 6 months post remission

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7
Q

Depression management

A

1:Watchful waiting 2 weeks
2: Group cbt/digital CBT, non directive supportive tx for 2-3months
3: Individual cbt, …
4th: fluxetine
5th: Sertraline or citalopram (SSRI)

still resistant?- ECT

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8
Q

Ptsd tx

A

1st: CBT
2nd: EMDR (eye therapy thing)

Exposure is key ingredient of successful psychological therapy

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9
Q

Complex ptsd tx

A

Phased treatment;
Stabilisation and safety (resourcing): enhance coping etc

Trauma tx (reprocessing): working through traumatic experience, cptsd

Rehabilitation

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10
Q

Medication for ptsd

A

if used: venlafaxine or SSRI eg. sertraline
severe - risperidone
drug tx should not be a routine first line tx for adults

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11
Q

Ocd mild tx

A

CBT including Exposure and Response Prevention (ERP)

2nd: SSRI or more intense CBT

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12
Q

moderate OCD tx (1st and second line drug)

A

1st: SSRI/ more intensive CBT (including ERP)
2nd line drug- clomipramine

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13
Q

severe OCD tx

A

refer to secondary care mental health team for assessment

whilst awaiting assessment offer combined treatment with an SSRI/clomiparine and CBT (including Exposure Response Prevention)

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14
Q

first line tx for parkinsons with quality of life affected by motor symptoms

A

levodopa

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15
Q

first line tx for parkinsons if motor symptoms are not affecting patients quality of life

A

dopamine agonist
or
levodopa
or
monoamine oxidase

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16
Q

give an example of a short acting benzodiazapene

A

lorazepam

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17
Q

give 2 examples of long acting benzodiazepines

A

chlordiazepoxide and diazepam

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18
Q

alcohol withdrawal tx
first second line

A

1st line: . chlordiazepoxide or diazepam
2nd: carbamezapine (anti-convulsant)

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19
Q

how long should antidepressants be continued

A

at least 6 months after remission of symptoms to decrease risk of relapse

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20
Q

generalised anxiety disorder drug treatment

A

1st line: sertraline
2nd: alternative ssri or SNRI
3rd: if neither SSRI or SNRI tolerated offer pregabalin

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21
Q

generalised anxiety disorder step wise approach

A

step 1: education about GAD + active monitoring
step 2: eg. guided self help
step 3: eg cbt or drug treatment.
step 4: highly specialist input e.g. Multi agency teams

22
Q

SSRIs are associated with inc risk of suicide in the under… agr group. therefore a review must be done within …. of commencing SSRI

A

under 30

review within 1 week of commencing

23
Q

if OCD tx with ssri is effective, how long must it be continued

A

at least 12 months to avoid relapse

24
Q

what type of drug is clomipramine

A

tricyclic antidepressant

25
how do tricyclic antidepressants work and SE
inhibit re-uptake of noradrenaline and toa lesser extent serotonin antagonism of : histamine receptors (drowsiness), muscarinic receptors (dry mouth, blurred vision, constipation etc), adrenergic receptors (postural hypotension) lengthen QT interval
26
which antipsychotic reduces seizure threshold
clozapine
27
which atypical antipsychotic has the most tolerable side effect profile
apiprazole- particularly for prolactin elevation
28
give 2 examples of SNRIs
duloxetine and venlafaxine
29
what are the risks of SSRI use in pregnancy
first trimester -congenital defect (paroxetine inc risk) use during third trimester can cause persistent pulmonary hypertension of the newborn
30
how often are lithium levels checked
lithium levels checked weekly until levels stable, includes after dose change, after stable, check every 3 months
31
panic disorder tx
1st line: CBT 2nd: SSRIs 3rd: clomipramine- (tricyclic)
32
escitalopram drug- what is it
SSRI
33
what is clomipramine
tricyclic antidepressant
34
antipsychotics: avoidance of EPSE (extrapyramidal side effects)
give atypical
35
antipsychotics: less sedating
give haloperidol, risperidone
36
antipsychotics: more sedating
give Olanzipine, Chlorpromazine.
37
antipsychotics: Avoidance of weight gain
give Haloperidol, Aripiprazole.
38
antipsychotics: treatment resistant
give clozapine
39
antipsychotics: depot
give risperidone
40
SSRIs se
hyponatraemia sexual dysfunction worsening symptoms
41
what substances have anti-convulsant properties and therefore can cause.... when suddenly stopped (non epileptic drugs)
benzodiazipines alcohol
42
heroin overdose tx
naloxones
43
paracetamol overdose tx
<1 hour - activated charcoal >1 hour- acetylcysteine
44
absolute contraindication to ECT
raised ICP
45
benzos act on what receptor
gaba A agonists (increase nurone inhibition)
46
benzodiazapines reversal drug
flumazenil
47
what antidepressant has a self harm risk
SSRI
48
monamine oxidase inhibitor mechanism of action se
prevents removal of monamines froms ynaptic cleft can cause hypertensxive crisis if taken with substances contining tyramine eg cheese alcohol
49
serotonin syndrome tx
benzo for agitation sever: ventilation and sedation
50
opiod detox tx
methadone full agonist, oral solution buprenorphine- partial agonist, oral tablet
51
delirium tremens tx
long acting benzo eg. chloropioxide