Psychedelic misuse Flashcards

1
Q

Psychedelics

A

-produce non-ordinary and variable forms of conscious experiences
-changes in moods, thoughts, sensations

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2
Q

Delusion

A

-fixed, false belief, unresponsive to logic
-paranoia

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3
Q

Hallucination

A

-false perception arising from internal stimuli
-creates false reality

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4
Q
A
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5
Q

Psychedelic classes

A

-classical: phenethylamine and trytamine derivatives
-dissociative: phencyclidine, ketamine, muscimol

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6
Q

Phenethylamine serivatives

A

-mescaline
-MDA
-MDMA

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7
Q

Derivatives of tryptamine

A

-DMT
-5-MeO-DiPT
-LSD
-Ibogaine

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8
Q

Naturally occuring classical psychedlics

A

-Dimethyltyrptamine (DMT)
-5-MeODMT
-psilocybin prodrug of psilocin

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9
Q

Mescaline

A

-3,4,5-trimethoxyphenethylamine

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10
Q

Mescaline and Phenethylamine

A

-amphetamine like (MDMA, bathsalts)
-inc release of 5-HT > DA, NE
-empathogens/entactogens (more hallucinogenic than stimulatory)
-llowest potency
-long lasting
-cross tolerance to LSD

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11
Q

most classical psychs MOA

A

-5-HT2A agonists
-pretreatment w antagonists blocks effects
-BUT MDMA stimulates 5HT2A release
-increase global integration, communication patterns of CNS

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12
Q
A
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