Psychosis

Question 1

Effects of Schizophrenia

Answer 1

Cognitive dysmetria might contribute to:
hallucinations, delusional thinking, disorganized patterns of thought and speech, emotional inappropriateness, and impaired attention.

Question 2

As genetic relatedness increases, so does the risk for schizophrenia. . The ____gene has been most clearly implicated in the development of schizophrenia

Answer 2

DISC1

Question 3

Number of alterations in brain structure?

Answer 3

Reduced volume in left frontal lobe

Reduced volume in left thalamus

Altered connections between thalamus and other structures

Consistent with neurodevelopmental hypothesis

Question 4

Antagonist of D2 dopamine receptor

Answer 4

Help control positive symptoms

Number of side effects:
Extrapyramidal syndrome
Tardive dyskinesia
Neuroleptic malignant syndrome
Hyperprolactinemia

Question 5

Antagonists for 5-HT2A and D2 receptors

Answer 5

Effective for positive, negative, and cognitive symptoms

Less risk of typical antipsychotic side effects

Associated with weight gain, cardiovascular effects, and agranulocytosis

Question 6

Elevated mesolimbic dopamine is associated with ________, and reduced dopamine in prefrontal cortex are associated with __________

Answer 6

positive symptoms

negative symptoms and cognitive impairments