PSYCHOTROPIC MEDS Flashcards

(62 cards)

1
Q

antipsychotics: target symptoms

A

positive symptoms; agitation, hallucinations, delusions, combativeness/belligerent behavior, sleep disturbance, tension, paranoid behavior/disorganized thinking

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2
Q

antipsychotics: symptoms less likely to respond

A

negative symptoms; impaired judgement, lack of insight, depression and withdrawal, poor motivation

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3
Q

antipsychotics: side effects

A

sedation, postural hypotension, weight gain, photosensitivity, sexual dysfunction, breast swelling, anticholinergic (dry mouth, blurred vision, urinary hesitation, constipation), tardive dyskinesia, acute dystonic reactions (involuntary muscle spasms or tightening of face), neuroleptic malignant syndrome (medical emergency, fever, muscle rigidity, mental status changes)

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4
Q

antipsychotics: tardive dyskinesia side effect treat

A

limit antipsychotic exposure, use vitamin E for prevention

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5
Q

antipsychotics: extrapyramidal symptoms (parkinsonian movements) treat

A

Artane, Cogentin, benadryl

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6
Q

antipsychotics: common atypical; clozapine

A

clozaril
different action
side effects–high saliva production, sedation, nausea, hypotension, dizziness, weight gain, risk of seizures; no tardive dyskinesia
need for weekly blood monitoring

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7
Q

antipsychotics: common atypical; resperidone

A

riserdal
injectable
side effects; sedation, some headache, dry mouth, constipation, blurred vision, palpitations, no tardive dyskinesia
question of relief for positive and negativesymptoms

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8
Q

antipsychotics: newer meds

A
apriprazole--abilify 
ziprasidone--geodon
quetiapine--seroquel 
olanzapine--zyprexa
asenapine-saphris
paliperidone palmitate--invega sustenna
paliperidone-invega
illoperidone--fanapt
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9
Q

tricyclic antidepressants: side effects

A

autonomic, anticholinergic (dry mouth, blurred vision, constipation, urinary probs, sweating/heat sensitivity), pustural hypotension, tachycardia, change in EKG arhythmias

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10
Q

tricyclic antidepressants: contraindicated for

A

people with heart disease, lethal in high doses so not good for suicidal pts

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11
Q

tricyclic antidepressants: therapeutic effects in

A

2-3 weeks

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12
Q

monoamine oxidase inhibitors (MAOIs): most effective for

A

atypical and nonendogenous depression

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13
Q

monoamine oxidase inhibitors (MAOIs): side effects

A

hypertension with high dose or when tricyclic/stimulant also taken

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14
Q

monoamine oxidase inhibitors (MAOIs): adverse drug reactions

A

stimulants, appetite suppressants, cold remedies, cocaine derivatives, anything that raises blood pressure

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15
Q

monoamine oxidase inhibitors (MAOIs): dietary restrictions

A

food with high levels of tyramine; avoid beer/ale, wine, cheese, smoke/pickled fish, beef/chicken liver, summer sausage, italian beans, yeast vitamin supplements

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16
Q

second generation antidepressants: benefits

A

reduced, different side/averse effects

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17
Q

second generation antidepressants: SSRIs therapeutic efficacy similar to

A

TCAs (tricyclic acids)

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18
Q

second generation antidepressants: SSRIs side effects are dose related

A

weight loss, nausea, diarrhea, nervousness (fluoxetine/prozac), insomnia, sexual dysfunction with long term use, less toxic to heart and safer in overdose than TCAs

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19
Q

second generation antidepressants: SNRIS side effects dose related

A

dry mouth, loss of appetite, nausea, diarrhea, constipation, nervousness, insomnia, elevated blood pressure and sexual problems
less toxic and safer in overdose

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20
Q

mood stabilizers: lithium

A

narrow therapeutic index; need blood levels/kidney/thyroid checked regularly

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21
Q

mood stabilizers: lithium side effects

A

thyroid can enlarge and underactive (treat with thyroid replacement meds)
renal kidney impact, need to drink more water for dehydration
gastrointestinal (anorexia, cramps, nausea, vomiting)
CNS (mental dullness, decreased memory and concentration, headache, hand tremors, fatigue and lethargy, weight gain)

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22
Q

mood stabilizers: lithium; don’t take

A

during first trimester of pregnancy

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23
Q

mood stabilizers: sometimes combined

A

with antidepressant or antipsychotic

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24
Q

mood stabilizers: therapeutic effect

A

2+ weeks to build dosage to therapeutic level, need LI does multiple times a day

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25
mood stabilizers: response rate
70-90% with typical bipolar respond, most effective at preventing mania not depression
26
mood stabilizers: anticonvulsants to stabilize mood; carbamazepine
tegretol avoid during pregnancy, may depress bone marrow function (blood count monitoring) patient needs to report signs of infection or bleeding ASAP
27
mood stabilizers: anticonvulsants to stabilize mood; valproic acid
depakote more effective for rapid cycling and mixed bipolar avoid during pregnancy
28
anxiety medications: panic disorder with or without agoraphobia
TCAs, MAOIs, SSRIs, alprazolam/xanax
29
anxiety medications: OCD
TCAs (clomipramine/Afafranil), MAOIs, SSRIs (fluvoxamine/Luvox, sertraline/Zoloft)
30
anxiety medications: specific phobias and social phobia
``` beta blockers (propanolol) to treat somatic symptoms of stage fright paxil for social phobia ```
31
anxiety medications: GAD, benzos; side effects
impaired muscle coordination, impairment of short term memory
32
anxiety medications: GAD, benzos; can also be used for detox of
alcohol or other depressants to prevent seizures
33
anxiety medications: GAD, benzos; safer and more effective than
barbiturates
34
anxiety medications: GAD, benzos; treatment issues
chronic use vs PRN, relapse vs withdrawal after meds discontinued, abuse liability, hard to discontinue, over use; drug most often used in overdose
35
anxiety medications: GAD, barbiturates
high abuse potential/safety problem, hard to separate anxiolytic and sedative doses, dangerout when used with alcohol
36
anxiety medications: GAD, barbiturates formerly used
methaqualone (quaaludes), hydroxyzine (atarax, vistaril), meprobamate (Milltown)
37
anxiety medications: GAD; antipsychotics
no more effective than benzos, more side effects, combo with anxiolytic in psychotic patient with high anxiety
38
anxiety medications: GAD, can use buspirone/buspar but
takes 2-6 weeks to relieve symptoms and not as good a PRN option
39
meds for sleep (hypnotics): benzos have less probabilty to tolerance
to hypnotic effects than with barbiturates
40
hyperactivity in kids: psychostimulants are standard: side effects
insomnia, decreased appetite, stomachace, headaches, jitteriness
41
hyperactivity in kids: meds; methylphenidate
ritalin and concerta
42
hyperactivity in kids: meds; amphetamine
adderall
43
hyperactivity in kids: meds; pemoline
cylert
44
hyperactivity in kids: meds; lisdezamfetamine
vyvanse
45
hyperactivity in kids: meds; other options; aripiprazole, ziprasidone, guanfacine, cloridine
ability, geodon, intuniv, kaprav
46
autism spectrum; not approved by FDA but use
SSRIs, TCAs, psychoactive antipsychotics, stimulants, antianxiety meds
47
``` Thorazine/chlorpromazine Stelazine/trifluoperazine Mellaril/thioridazine Prolixin/fluohenazine (prolixin D injectable) Navene/thiothixene Haldol/haloperidol ```
Typical antipsychotics
48
Clozapine/clozaril Reperidone/risperdal (available as injectable) ``` Apriprazole/abilify Ziprasidone/geodon Quetiapine/seroqeul Olanzapine/zyprexa Asenapine/saphris Paliperidone palmitate/inveva sustenna Paliperidone/invega Illoperidone/fanapt ```
Atypical antipsychotics
49
``` Imipramine/tofranil Amitriptyline/elavil Nortriptyline/aventyl, pamelor, norpress Desipramine/norpramin, pertofrane Doxepin/adapin, deptran, sinequan ```
Tricyclic antidepressants
50
Phenelzine/Nardill Tranylcypromine/parnate Isocarboxazid/marplan
MAOIs (Minoan is oxidase inhibitors) antidepressant
51
``` Amoxapine/asendin Trazadone/desyrel Maprotiline/ludiomil Bupropin/Wellbutrin Venlaxafine/Effexor Nafazadone/serzone ```
Second generation antidepressants
52
Fluoxetine/Prozac Sertraline/Zoloft Paroxetine/Paxil Vilazodone/vilbryd
SSRIs
53
Duloxetine/cymbalta | Desvenlafaxine/pristiq
SNRIs
54
Lithium
Mood stabilizer
55
``` Carbamazepine/tegretol Valproic acid/depakote Gabapentin/neurontin Lamotrigine/lamictal Toprimate/topomax ```
Anticonvulsants to stabilize mood
56
Panic disorder with or without agoraphobia
TCAs, SSRIs, MAOIs, Xanax/alprazolam
57
OCD
TCA MAOI SSRI (Luvox/fluvoxamine, sertraline/Zoloft)
58
``` Beta blockers (propranolol) Paxil ```
Somatic symptoms of stage fright | Social phobia
59
Diazepam/Valium Chlordiazepam/Librium Lorazepam/Ativan Clorazepate/tranxene
Benzos
60
Amobarbital Secobarbital Penobarbital
Barbiturates
61
Benzos Flurazepam/dalmare Triazolam/halcion Temazepam/restoril Barbiturates-chloral hydrate Trazadone/desyrel Eszopicione/lunesta Zolpidem/ambien Zaleplon/sonata Ramelteon/rozerem
Sleep aids/hypnotics
62
Donepezil/aricept | Mamantine/name day
Dementia meds