Pulmlecture4 asthma Flashcards

(38 cards)

1
Q

Which lung cancer has the least favorable prognosis?

A

Small call lung cancer (15% of lung cancers)

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2
Q

Can NSCLC be cured?

A

Yes, surgical resection is favorable for

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3
Q

When is NSCLC surgery contraindicated?

A

when distant metastasis is present(stage 4), malignant pleural effusion, or when the tumor is in an area close to other important structures or if the patientís health is generally poor

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4
Q

When are most small cell lung cancers diagnosed? prognosis?

A

70% dx when there is extensive dz/ most live for only one year- generally poor prognosis d/t late dx

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5
Q

Can SCLC be cured?

A

No, surgery is not an option(usually). Chemotherapy is best treatment

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6
Q

When do patients receiving chemotherapy have the most side effects?

A

N/V starts about 3rd day of each cycle

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7
Q

When you see a mass on you patients CT: what are some benign tumor types that you could reassure your patient with?

A

Benign: Granulomas, Hamartoma(peripheral lung nodule), Bronchial gland adenoma(can present as tracheobronchial obstruction) Low- grade malignant:Carcinoid tumor(95% cure rate), Bronchial gland carcinoma(can reoccur)

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8
Q

You found a solitary nodule on your patients lung field: what would be some reassuring characteristics that you might see?

A

smooth, calcified and less than 3 cm–or if the lesion has not changed in 2 years

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9
Q

Same patient: What are you going to do?

A

you can ìwatch and waitî or do aggressive diagnostics for pathology ìwatch and waitî is good for a pt who cannot tolerate a procedure, have few rests for lung cancer.

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10
Q

Same patient: Pt is ambivalent about next step to take. What are some statistics that would help you educate your pt?

A

> 65yo = 65% chance malignant cancer , >3cm =75% chance lung cancer, spiculated mass in upper lobe=75% lung cancer

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11
Q

When should you proceed to order a PET scan for a solitary pulmonary nodule?

A

if the mass is greater than 1cm

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12
Q

Allergic rhinitis is pretty common: What are some clues that your patient might have it (history/PE/comorbidities)?

A

History: atopy, allergic asthma, parent with allergies, male, living environment with triggers, PE: sneezing, ITCHY, post nasal drip/throat clearing, rhinorrhea, ìallergic faciesî, dennie-Morgan lines, allergic siners, cobblestoning comorbidities: OSA, allergic conjunctivitis, otitis media w/ effusion, NASAL POLYPsis, ASTHMA, sinusitis, URI

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13
Q

Your patient does have allergic rhinitis- how do you manage this patient?

A

allergy avoidance(dust mites, pets, cockroaches, indoor molds, outdoor allergens), Antihistamines, nasal corticosteroids, decongestants, mast cell stabilizer, anticholinergics, leukotriene- receptor antagonist HEPA filter,

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14
Q

You give your patient with allergic rhinitis a H1 blocker, but it isn’t resolving the symptoms. What do you do?

A

Step up the therapy, add decongestant, then add intranasal CS, then increase doses, and if that all this still fails(refractory AR) send for surgical referral

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15
Q

A parent brings their 1 year old into your clinic and she is displaying the typical ìallergic faciesî. How do you manage this patient?

A

Refer out- patients under 2 yo donít have allergic sensititzation developed yet- something bigger happening….

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16
Q

What are the 2 components of asthma you treat?

A

smooth muscle dysfunction(bronchocontriction-SABA and LABA) and airway inflammation (ICS)

17
Q

What WBC are involved with Asthma versus COPD

A

Asthma=eosinophils COPD=neurtophils

18
Q

You are taking on a new patient with asthma and are worried about potential for adverse events. What history increases risk for adverse events like fatal asthma?

A

> 2 ER or hospitalizations in past year for asthma, prior ICU admission or prior intubation in past 5 years, recent oral steroid usage, use of >2 canisters of SABA a month, pt with denial about perceived airflow obstructions, history of sudden severe exacerbations,

19
Q

What are some triggers of asthma?

A

VIRAL infections, mold, animals, GERD, nighttime, smoke,

20
Q

What is the gold standard for diagnosing asthma?

A

spirometry with bronchodilator- should show reversibility= FEV1 increase by 12-15% or >200ml

21
Q

Your patient has a NSAID allergy and asthma, what do you want to look for?

22
Q

What are some differing symptoms of asthma versus COPD?

A

asthma: 40 yo, PROGRESSIVE, frequent sputum

23
Q

What symptoms present with VocalCordDysfunction?

A

throat symptoms, inspiratory stridor, dysphonia, no response to SABA,

24
Q

Your asthma patient seems to have some sort of infection, the symptoms include fever, brown mucus plugs and eosinophilia on blood smear. What is your diagnosis?

A

Allergic bronchopulmonary aspergillosis(ABPA). Tx with prednisone and itraconazole (antifungal)

25
What other conditions are predisposed to ABPA?
Cystic Fibrosis pts. (and asthma)
26
Explain Samterís syndrome
Asprin/NSAID allergy, asthma and nasal polyps, found more in women, results in shunting of arachidonic acid causing bronchoconstriction
27
What is the rule of one-thirds in pregnancy with asthme?
1/3- asthma gets worse, 1/3-asthma gets better, 1/3 asthma stays the same
28
What are category B asthma medications for pregnant women?
Budesonide, montelukast, xolair, cromolyn, category C-albuterol, ICS, theophylline, DO NOT use tetracycline, sulfa or cipro
29
What medications are used in asthma, but not COPD?
Leukotriene modifirs(agonist) and IgE antagonists
30
Reliever medications for asthma are__________?
PRN- SABA, burst oral steroid, anticholinergics for cough
31
Controller medications of asthma?
ICS, LTRA, ICS/LABA combo, throphylline, Anti-IgE
32
Continuous nebulization of children may be more effective than MDI, but you need to watch out for what?
Lactic acidosis
33
What prophylaxis must you provide with ICS?
Bone density risk- keep Vitamin D3 levels in check, calcium citrate supplements, wt bearing exercise
34
Theophylline
Not helpful with acute exacerbation, many side-effects, many interactions, worsens GERD, NOT RECOMMENDED, but cheap
35
SALSA for asthma severity/ control is?
Symptoms, Activity, Lung funtion, SABA use, Awakenings
36
what is the FEV1 stepwise for asthma severity?
normal to >80%predicted [intermittent], >80% predicted)[mild] ,between 80%-60% [moderate],
37
What is the stepwise progression of add on therapies for asthma?
SABA+low dose ICS+med dose ICS or LABA/ICS +Medium dose ICS/LABA+High dose ICS/LABA (+omalizumab if allergy related)+ high dose/LABA/oral steroid
38
What are 4 components of QOL that providers should periodically assess for in asthma management?
1.missed work or school d/t asthma 2.reduction in usual activities 3. sleep disturbances d/t asthma 4. changes in caregiver activities d/t childís asthma(obvs for children with asthma)