Pulmonology #6 (Respiratory Infections) Flashcards

(39 cards)

1
Q

What happens if you try to treat children under 18 with Aspirin?

A

Reye Syndrome!! has a 30% fatality rate

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2
Q

Symptoms of influenza

A

-Abrupt onset of headache, fever, chills, malaise, myalgias (involving legs)
-Dry cough, eye pain, GI symptoms

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3
Q

What diagnostics can be done for influenza?

A

rapid nasal swab or viral cultures

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4
Q

Treatment for influenza…

Who gets antivirals?

A

Supportive: Acetominophen

Antivirals: is hospitalized or 65 years or older
–Oseltamivir within 48 hours of symptom onset (not given under 12 years old)
–If in a long-term facility, all residents get it regardless of vaccine history

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5
Q

What are contraindications to BOTH flu vaccines?

A

Anaphylaxis to vaccine

Guillan-barre Syndrome within 6 weeks after a flu vaccine

High fever

Infants < 6 months of age

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6
Q

Who can get the inactivated flu vaccine?

How about the live attenuated vaccine?

A

Inactivated: 6 months or older (including pregnancy)

Live: 2-49 years old

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7
Q

What are contraindications to the live attenuated flu vaccine?

A

Immunocompromised, pregnancy, 50 years or older, or have taken antivirals within the last 48 hours

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8
Q

What are the three phases of Pertussis (Whooping Cough)?

What phase are the children most contagious in?

Who does this normally occur in?

A

1) Catarrhal Phase: URI symptoms lasting 1-2 weeks
2) Paroxysmal Phase: severe coughing fits with inspiratory whooping after cough. Post-tussive emesis.
3) Convalescent Phase: resolution of cough

Catarrhal most contagious

Children under 2 years old

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9
Q

Treatment for Pertussis

A

-Supportive: oxygen, nebulizer
-Macrolides if needed

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10
Q

What is the vaccine schedule for pertussis?

A

DTap in 5 doses: 2, 4, 6, 15-18 months, 4-6 years old.

Booster at 11-18 years old.

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11
Q

What is the MCC of lower respiratory infection in children?

What is the key diagnostic to determine prognosis?

A

RSV

Pulse oximetry

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12
Q

Acute bronchitis is inflammation of the bronchi. It is MCC by ________.

What are some symptoms of this condition?

A

Viruses

Cough: present for at least 5 days, 1-3 weeks
-Malaise, dyspnea, hemoptysis
-Follows a URI
-Wheezing, Fever

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13
Q

How do you prevent acute bronchitis?

What’s the treatment?

A

H. Flu vaccine

Supportive: fluids, rest, humidifier

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14
Q

Acute bronchiolitis is infection of the bronchioles (smaller airways). This is MC in ______ and the MCC is ______

A

Children under 2 years old

RSV is the MCC

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15
Q

Symptoms of acute bronchiolitis

What is the treatment?

A

Viral prodrome for 1-2 days followed by respiratory distress

Supportive: IVF, humidified oxygen
-Handwashing is preventative

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16
Q

What can you give to prevent bronchiolitis?

A

Palivizumab if born < 29 weeks or has congenital heart disease

17
Q

Acute epiglottitis (Supraglottitis) is MC in _______ and what is the MCC? Remember this cause may have changed due to a vaccine.

What’s another cause in adults?

A

MC in 3 months - 6 years

H. Influenzae B MCC until vaccines (Hib).

If immunized, suspect Group A Strep

Cocaine is a cause in adults

18
Q

Symptoms of supraglottitis

A

Dysphagia, Drooling, Distress

-Odynophagia, fever, inspiratory stridor, tripping, hot potato voice
-Refuses to lie supine

19
Q

What is the definitive diagnostic for supraglottitis?

What is seen on XR?

What should you NOT do?

A

Laryngoscopy: cherry red epiglottis with swelling

Soft tissue lateral cervical XR: thumb or thumbprint sign (enlarged epiglottis)

Do not try to visualize with tongue depressor

20
Q

Treatment for supraglottitis?

A

Maintain airway first (OR best setting for intubation)

Prevention with Hib vaccine

ABX: Ceftriaxone or Cefotaxime

21
Q

What can you give to close contacts to prevent acute epiglottitis?

22
Q

MCC of Laryngotracheitis (Croup)

A

Parainfluenza Virus Type 1

23
Q

Symptoms of Croup

A

-Upper airway involvement (harsh, seal-like barking cough)
-Inspiratory stridor
-Hoarseness
-Low grade fever
-Symptoms worse at night
-Coryza (URI symptoms)

24
Q

What is seen on front cervical radiographs with Croup?

A

Steeple sign (subglottic narrowing of airway)

25
Treatment for Croup if... Mild Moderate Severe
Mild (no stridor at rest): Supportive, Dexamethasone for symptoms Moderate (stridor at rest with mild retractions): Dexamethasone and Nebulized Epi Severe: Dexa + Epi + Hospitalization
26
MC foreign body aspirated by children? Treatment
Peanuts Rigid bronchoscopy
27
Costochondritis and Tietze Syndrome are VERY similar in presentation, etiologies, and treatment. What are the etiologies, treatment, and differences in symptoms?
Etiologies: idiopathic, postural or posttraumatic (coughing, straining) Treatment: NSAIDs Symptoms: Pleuritic chest pain worse with inspiration. Reproducible point chest wall tenderness with palpation. Palpable edema ONLY in Tietze Syndrome (none in Costochondrititis)
28
What is acute respiratory distress syndrome? What is the biggest risk factor for this condition?
Severe inflammation of the lung tissue that impairs gas exchange secondary to acute injury --> pulmonary edema --> capillaries get leaky --> oxygen doesn't transfer within the lungs Gram-negative Sepsis
29
Symptoms of ARDS
-Acute dyspnea and hypoxemia -Frothy red sputum -Tachypnea -Diffuse crackles -Severe hypoxemia refractory to suppemental oxygen (Low O2 that doesn't improve)
30
What diagnostics are done for ARDS?
CXR: diffuse bilateral pulmonary infiltrates (like CHF but spares costophrenic angles) PCWP < 18mmHg with right heart catheterization (in CHF it is > 18)
31
Treatment for ARDS
-Intubation and PEEP improves hypoxemia
32
What is hyaline membrane disease/Respiratory distress syndrome?
Occurs in premature infants due to insufficient production of surfactant
33
True or False: Hyaline membrane disease is MCC of death in the first month of life?
True
34
By _____, enough surfactant is produced in the lungs. Symptoms of hyaline membrane disease
35 weeks -Presents shortly after birth with respiratory distress. -Tachypnea -Tachycardia -Chest wall retractions -Nasal flaring, cyanosis, respiratory grunting
35
Treatment for hyaline membrane disease
-Antenatal glucocorticoids given if premature birth expected (before 34 weeks) -Exogenous surfactant via endotracheal tube to open alveoli -CPAP oxygen +/- intubation
36
Sleep apnea is involuntary cessation of breathing during sleep. Risk factors for this condition include.... There are two types. Explain them.
Obesity***, Males, Older age Central: reduced CNS respiratory drive Obstructive: physical airway obstruction
37
Symptoms of sleep apnea
-Snoring, unrestful sleep, hypersomnia, nocturnal choking -Large neck circumference -Crowded oropharynx -Micrognathia (lower jaw undersized)
38
Diagnostics for sleep apnea
-In lab polysomnography (first line): 15 or more events/hour -Epworth Sleepiness Scale
39
Treatment for sleep apnea
-Behavioral changes: weight loss, no alcohol, changes in position to sleep -CPAP -Oral appliances -Tracheostomy is definitive