QUALITY CONTROL Flashcards
(49 cards)
Is a system of ensuring accuracy & precision in the laboratory by including quality control reagents in every series of measurements
Quality Control
is a systematic action necessary to provide adequate confidence that laboratory services will satisfy the given medical needs for patient care
Quality Assurance
material of known concentration used in developing a standard curve and/or instrument calibration
Standard
sample of known quantity with several analytes present
Control
2 Types of Quality Control
- Interlab QC
2. Intralab QC
2 Levels of control solutions in General Chemistry
- Pathologic
2. Non-Pathologic
QC done within the Laboratory
Intralab Quality Control
Maintaining long term quality control
Involves proficiency testing programs that periodically provide samples of unknown concentrations to participating clinical laboratories
Determine state-of-the-art of the analytical methods
Interlab quality control
Internal QC
Intralab Quality Control
External QC
Interlab quality control
Gold standard for clinical laboratory external QC testing
College of American Pathologists (CAP)
Intralab QC Is done every ______
Everyday
Immuno Assays QC Level
- Low QC
- Normal QC
- HIgh QC
Ability of an analytical method to measure the smallest concentration
Sensitivity
Is the Ability of an analytical method to measure ONLY the analyte of Interest
Specificty
Is the Nearness or Closeness of the Assayed value to the true or target value
Accuracy
The ability of an analytical method to give repeated results on the same sample that agree with one another
Precision
The degree by w/c a method is easily repeated.
Practicability
The ability of an analytical method to maintain accuracy & precision over an extended period of time during w/c equipment, reagents, & personnel may change
Reliability
Other name for precision
Reproducibility
The Ability of an analytical method to detect the proportion of individuals with the disease. (Screening tests require high sensitivity)
Diagnostic Sensitivity
The Ability of an analytical method to detect the proportion of individuals without the disease. (Confirmatory tests require high specificity)
Diagnostic Specificity
highest frequency occurs with the use of handwritten labels and request forms
Clerical Error
Random Error Vs. Systematic Error
Random Error>Varies from sample to sample
>Present in all measurement
>Due to chance
Systematic Error> Error that influences observations consistently in one directions
