Quiz 1 Part 2 Flashcards

1
Q

Are the circulatory and lymphatic systems completely separated?

A

no! there is some exchange

the “plasma” part of blood is lymph

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2
Q

does the lymph system have a pump?

A

no- the circulatory system has the heart, but the lymph system moves with the movement of the body and has valves to prevent backward flow

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3
Q

Efferent lymphatic vessels travel where?

A

LEAVES lymph node and enters blood circulation at a vein

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4
Q

Where does circulatory exchange take place?

A

at a lymph node

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5
Q

What is meant by a “draining” lymph node

A

one that has been activated by a pathogen

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6
Q

Lymphocytes and lymph return to the blood via….

A

lymphatics

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7
Q

Pathogens from the site of infection reach lymph nodes via…

A

lymphatics

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8
Q

What is a “naive” lymphocyte

A

those that have not encountered an antigen. they arrive at lymph nodes via arterial blood

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9
Q

The adaptive immune response is ____based

A

antibody

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10
Q

WHERE does the innate immune response take place?

A

at the site of infection

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11
Q

Where does the adaptive immune response take place

A

lymphatic tissue, lymph nodes

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12
Q

Describe the structure of a lymph node

A

B and T cells (lymphocytes) segregate into follicles

afferent and efferent lymphatic vessels allow the entry and exit of interstitial fluid

unstimulated (naive) lymphocytes circulate between blood and lymph

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13
Q

What do afferent lymphatic vessels do in relation to a lymph node

A

at an afferent lymphatic, Interstitial fluid goes IN to the lymph node

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14
Q

How many afferent vessels are usually attached to a lymph node>

A

MULTIPLE

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15
Q

What is happening at an efferent lymphatic vessel? how many are there at a lymph node?

A

lymph LEAVES a lymph node through an efferent lymphatic. it meets up with the heart at the subclavian vein. ONLY ONE

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16
Q

Besides afferent and efferent vessels, what else allows entry and exit into and out of a lymph node?

A

an artery and a vein allow the exchange of blood

17
Q

a lymphoid follicle is mostly made up of ____ cells

A

B

18
Q

What is a germinal center?

A

circular piece of a lymph node. it cranks out antibodies that are specific to the pathogen presented

19
Q

____ and ____ go into and out of a lymph node

A

blood and lymph

20
Q

Through which structure must antibodies leave a lymph node to be able to reach the site of infection?

A

it doesn’t matter. the lymphatics eventually meet the subclavian vein and go into the blood anyway. The antibodies will reach the site of infection regardless

21
Q

Resident macrophages are ___ living

A

long

22
Q

What is the purpose of dendritic cells in the innate immune response?

A

to carry the pieces from the destruction of the pathogen to the lymph node through an afferent lymph vessel. present the pathogen to the T cells and B cells

23
Q

What is the purpose of the plasma cells in the lymph node?

A

to secrete antibodies

24
Q

Within a lymph node, _____T cells are entering and ____ T cells are exiting

A

unstimulated are entering (through an artery/afferent lymphatic)
Activated T cells are leaving(through a vein/efferent lymphatic)

25
Q

Name the primary lymphoid tissues

A

bone marrow and the thymus

26
Q

What do you mean by “PRIMARY” lymphoid tissue?

A

the bone marrow and the thymus actually make lymphocytes

27
Q

name the SECONDARY lymphoid tissues

A

-spleen
-adenoids
-tonsils
-appendix
-lymph nodes
-peyer’s patches
-mucosal surfaces

28
Q

All of the secondary lymphoid tissues function the same way as….

A

a lymph node

29
Q

in which organ are peyer’s patches located. what exactly is it?

A

well organized lymphoid follicles in the small intestine

30
Q

What is the primary function of the spleen??

A

filtering blood

31
Q

Contrast the function of red pulp and white pulp

A

Red pulp— red blood cell monitoring and removal

white pulp — similar structure and function as a lymph node

32
Q

Pathogens that have entered the bloodstream or have escaped degradation in lymph nodes are removed by…

A

the spleen

33
Q

Describe the basic structure of red pulp and white pulp in the spleen

A

“plum pudding” —–red pulp takes up most of the room and the white pulp is in circles inside of the red pulp

34
Q

Explain what GALT BALT and MALT are

A

GALT = gut associated lymphoid tissue
-tonsils, adenoids, appendix, peyer’s patches

BALT bronchial associated lymphoid tissue (lungs)

MALT=mucosa associated lymphoid tissue (includes GALT and BALT combined)

35
Q

How are pathogens delivered to GALT from the blood?

A

by means of specialized M cells in the epithelium. M cell is like a gate. very selective entry because we dont want the good bacteria getting in

36
Q

If lymphocytes are not activated in GALT, where do they exit through?

A

efferent lymphatics

37
Q
A