Quiz 1 Part 2 Flashcards
Are the circulatory and lymphatic systems completely separated?
no! there is some exchange
the “plasma” part of blood is lymph
does the lymph system have a pump?
no- the circulatory system has the heart, but the lymph system moves with the movement of the body and has valves to prevent backward flow
Efferent lymphatic vessels travel where?
LEAVES lymph node and enters blood circulation at a vein
Where does circulatory exchange take place?
at a lymph node
What is meant by a “draining” lymph node
one that has been activated by a pathogen
Lymphocytes and lymph return to the blood via….
lymphatics
Pathogens from the site of infection reach lymph nodes via…
lymphatics
What is a “naive” lymphocyte
those that have not encountered an antigen. they arrive at lymph nodes via arterial blood
The adaptive immune response is ____based
antibody
WHERE does the innate immune response take place?
at the site of infection
Where does the adaptive immune response take place
lymphatic tissue, lymph nodes
Describe the structure of a lymph node
B and T cells (lymphocytes) segregate into follicles
afferent and efferent lymphatic vessels allow the entry and exit of interstitial fluid
unstimulated (naive) lymphocytes circulate between blood and lymph
What do afferent lymphatic vessels do in relation to a lymph node
at an afferent lymphatic, Interstitial fluid goes IN to the lymph node
How many afferent vessels are usually attached to a lymph node>
MULTIPLE
What is happening at an efferent lymphatic vessel? how many are there at a lymph node?
lymph LEAVES a lymph node through an efferent lymphatic. it meets up with the heart at the subclavian vein. ONLY ONE
Besides afferent and efferent vessels, what else allows entry and exit into and out of a lymph node?
an artery and a vein allow the exchange of blood
a lymphoid follicle is mostly made up of ____ cells
B
What is a germinal center?
circular piece of a lymph node. it cranks out antibodies that are specific to the pathogen presented
____ and ____ go into and out of a lymph node
blood and lymph
Through which structure must antibodies leave a lymph node to be able to reach the site of infection?
it doesn’t matter. the lymphatics eventually meet the subclavian vein and go into the blood anyway. The antibodies will reach the site of infection regardless
Resident macrophages are ___ living
long
What is the purpose of dendritic cells in the innate immune response?
to carry the pieces from the destruction of the pathogen to the lymph node through an afferent lymph vessel. present the pathogen to the T cells and B cells
What is the purpose of the plasma cells in the lymph node?
to secrete antibodies
Within a lymph node, _____T cells are entering and ____ T cells are exiting
unstimulated are entering (through an artery/afferent lymphatic)
Activated T cells are leaving(through a vein/efferent lymphatic)
