quiz 3 part b Flashcards
(32 cards)
Methylation pathway markers
Vitamin B12, folic acid
MMA
Methylmalonic Acid
MMA–> succinate (nutrient)
requires b12
MMA–> succinate (enzyme)
methylmalonyl CoA mutase
precursor to MMA
propionate
What is figlu
a folic acid marker
Figlu is an intermediate of
HIS
Figlu +THF–> glu +n5 requires
b9
FIGLU is
is an intermediate in the catabolism of L-histidine to L-glutamic acid and marker for intracellular levels of folate.
High figlu requires what supplementation for folate loading
THF
if tHCYS high, supplementation of what is required for folate unloading
5MTHF
high tHCYS is a marker for
b6,b9, or b12 deficiency
high MMA, normal tHCYS and FIGLU
B12
high tHCYS with normal figlu and MMA
b6 and betain
high tHCYS, MMa and FIglu
b6, b9, b12 and methyl donating nutrient
high tHCYS, MMa and FIglu
b6, b9, b12 and methyl donating nutrient
B9 deficiency is caused by
poor diet or lack of zinc
catecholamine metabolites
VMA, HVA
NMDA modulators
Kynurenate, quinolinate, picolinate
Serotonin metabolite
5-hydroxyindoleacetate (5HIAA)
nutrients required by NE/EPI–> VMA (7)
COMT, SAMe, Mg, MAO, B2, Cu, Fe
nutrients required for dopamine to HVA (7)
COMT, SAMe, Mg, MAO, B2, Cu, Fe
Phenyalanine to tyrosine (nutrients)
BH4, fe
Tyrosine to dopa( nutrients)
BH4 FE