Quiz #4 Flashcards
(45 cards)
____ - _____% of patients with sepsis die.
28-50%
Risk Factors for Sepsis (4)
- 65+ years old
- Pts with chronic medical conditions (DM, lung dz, CA, kidney dz)
- People with weakened immune systems
- Neonates
SIRS Criteria
- Body Temperature (>38 or < 36)
- Heart Rate (> 90 bpm)
- Tachypnea (> 20 breaths)
- WBC Count (> 12,000, < 4,000, or > 10% immature neutrophils)
Sepsis Steps
- Sepsis: presumed source of infxn + 2 or more SIRS criteria
- Severe sepsis: sepsis + organ dysfunction
- Septic shock: sepsis refractory to IV fluid (refractory hypotension) OR lactate > 4
Severe Sepsis Bundle
Within 3 hrs of presentation: 1. measure serum lactate 2. obtain blood cx prior to abx 3. administer abx 4. start IV fluids (LR/NS) 2.5 L/hr Within 6 hours of presentation: 1. repeat serum lactate if initial lactate > 2
IV fluid rate for peds in severe sepsis
40 ml/kg when septic
Septic Shock Bundle
Within 3 hours of presentation: 1. measure serum lactate 2. obtain blood cx prior to abx 3. administer abx 4. resuscitate with 30 ml/kg fluids Within 6 hours of presentation: 1. repeat volume status and tissue perfusion assessment 2. give vasopressors (if hypotension persists)
Top sources of sepsis infections
Lungs
Urinary tract
Skin
GI tract
Types of Headaches
Tension (most common - 40%)
Migraine
Cluster
DDX for headache
- Primary (tension, migraine, cluster)
- Vascular (hemorrhage, hematoma, aneurysm)
- Infectious (meningitis, abscess, encephalitis)
- Cancer
- Medical D/O (hypothyroidism, OCPs, fever, CO exposure)
Characteristics of Migraines (POUND)
Pulsatile Onset/Duration 4-72 hours Unilateral Nausea Disabling
Red Flags for Headaches
"Worst HA of my life" Thunderclap HA FND (atypical aura) Fever, nuchal rigidity, kernig's, papilledema > 50 y/o New onset in pregnancy Worsening pattern HA triggered by cough or exertion Recent trauma
Classifications for Migraines
At least 2 of the following:
- Unilateral
- Moderate to severe
- Pulsatile
- Aggravated by movement
1 of the following:
- Nausea
- Photo and phonophobia
At least 5 episodes
Auras of migraines
Visual - scintillating scotoma, photophobia
Sensory - paresthesia, numbness
Other - weakness, aphasia
Tx for migraines (acute)
NSAIDs Tylenol Triptans OTC Excedrin Fioricet Cafergot Goody's Powder Opiates Antiemetics
Tx for migraines (preventative)
Consider if 2+/month CCB (Verapamil) BB (Propranolol) TCA (Amitriptyline) Valproate Sodium Botox
Tx for tension HA (acute)
Aspirin Acetaminophen Ibuprofen Naproxen Excedrin
Tx for tension HA (chronic)
Amitriptyline
Fluoxetine
Tizanidine
Stop smoking
Tx for cluster HA
O2, ergotamines at first signs of sx Corticosteroids Verapamil Topiramate Valproic Acid
Associated symptoms with migraines
Nausea Vomiting Photophobia Phonophobia Aura
Associated symptoms with cluster HA
Ipsilateral lacrimation Ipsilateral redness of the eye Stuff nose Rhinorrhea Pallor Sweating Restlessness or agitation
Presentation of CVA
Sudden speech difficulty Weakness Paralysis Vision loss Dizziness Severe HA FAST (face, arm, speech, time)
DDX of stroke
Seizures Hypoglycemia Migraine with aura HTN encephalopathy Drug toxicity CNA abscess or tumor Wernicke's encephalopathy
Time since “last known normal” timeframes
< 4.5 hrs for tPA
< 6 hrs for endovascular thrombectomy