Quiz Flashcards
(46 cards)
the nucleus basalis of meynert is affected early in this disease
alzheimer’s disease
A trinucleotide repeat expansion of ‘CAG’ with choreic movements.
huntington’s disease
In this disease, degeneration of the midbrain leads to vertical gaze palsy.
progressive supranuclear palsy
Adults with this hereditary disease are associated with Alzheimer’s disease in
later life.
down’s syndrome
Loss of dopamineric neurons in the substania nigra.
PD
Resting tremor, rigidity and bradykinesia.
PD
hemiballism- associated diagnosis?
subthalamic lesion
Parkinsonism with orthostatic hypotension. Poor response to levodopa
multiple system atrophy
Widespread chorea due to rheumatic fever
sydenham’s
CSF: Clear, normal opening pressure with oligoclonal bands present
MS
Clear, normal opening pressure, lymphocytes present, high protein and
normal glucose
viral meningitis
Cloudy, elevated opening pressure, neutrophils present, high protein and low
glucose
bacterial meningitis
Opaque (if left to settle it forms a fibrin web), elevated opening pressure,
lymphocytes present, high protein and low glucose
TB meningitis
most useful diagnostic investigation in Alzheimer’s?
MMSE
most useful diagnostic investigation in frontotemporal dementia?
MRI
most useful diagnostic investigation in vascular dementia?
MRI
anti-epileptic drug: used in pregnancy. Side effects include a rash and Steven-Johnson
syndrome
lamotrigine
anti-epileptic drug: used as the first-line treatment for absence seizures. Blocks thalamic T-type
Ca2+ channels
ethosuxamide
Na+ channel inactivation with increase GABA concentration. Should be
avoided in females of childbearing age.
sodium valproate
best management option: a patient with uncontrolled hypertension developed a stroke.
anti-hypertensive medication
best management option: a patient had a seizure due to a cerebrovascular accident
carbamazepine (focal seizure)
A patient with atrial fibrillation developed a stroke (best long-term
management).
warfarin
Most useful Ix to order: A 65-year-old male patient presents to the clinic with double vision and ptosis. He also experiences weakness that gets worse during the day.
anti AchR Abs
A 20-year-old female with tonic clonic seizures wishing to conceive soon.
What is the medication of choice?
lamotrigine