Rabbit Medicine Flashcards
(241 cards)
1
Q
Name the symbiotic yeast found to line the stomach of rabbits
A
Cyniclomyce guttulatas (Saccharomycopsis guttulata)
2
Q
Gastric pH juvenile (preweaned rabbits)
A
5.0-6.5
3
Q
Gastric pH adult rabbit
A
1.0-2.0 (3.0 following ingestion cecotropes)
4
Q
Common ear mite in rabbits
A
Psoroptes cuniculi
5
Q
What comprises the GALT in rabbits
A
- Peyer’s patches (jejunum and distal ileum)
- Sacculus rotundus (ileocecal junction)
- Vermiform appendix (distal terminus of cecum)
6
Q
Role of vermiform appendix
A
Secrete water and bicarbonate into cecum for fermentation
7
Q
Four sections of LI
A
- ~10cm anterior (taeniae with three sacculated haustra)
- ~20cm single longitudinal taenia and haustrum
- separated by fusus coli which is unique to rabbits - ~4cm densely innervated and banded circumferentially with muscle and lacks taeniae and haustra with LOTS of goblet cells.
- Distal colon ~80-100cm from fusus coli to rectum. Short crypts and numerous goblet cells.
8
Q
What connects the ileum, cecum, and proximal colon?
A
ampulla caecalis coli
9
Q
What hormone mediates absorption of water, K+, and Na+ during digestion?
A
aldosterone
10
Q
What do cecal goblet cells produce
A
Mucin
11
Q
Digestible energy requirements in rabbits
A
400kJ/day^-1/kg^-1 x LW^0.75
12
Q
Raising cecal pH in rabbits fed high protein diets causes what?
A
Overgrowth of Clostridia and Escherichia in cecum
13
Q
What vitamins do cecotropes provide?
A
Vitamin K, Vitamin B
14
Q
Congenital progressive and fatal disorder of sodium transport in cecum is found homozygous in what breeds?
A
spotted (English Spot) and Checkered GIant breeds.
15
Q
Bacterial cause of enterotoxemia
A
Clostridium spiroforme
16
Q
What age group of rabbits is most commonly affected by clostridium spiroforme?
A
Newly weaned (3-6 weeks)
17
Q
Enterohemorrhagic E coli produces a shiga toxin that causes what clinical signs
A
hemorrhagic colitis with hemorrhagic diarrhea
18
Q
Rabbits naturally infected with enterohemorrhagic E coli develop what hallmark sign of the shiga toxin
A
thrombotic microangiopathy
19
Q
Subsequent litters of does infected with E coli may have passive immunity: T or F
A
True
20
Q
What antibiotics are used to treat enteropathogenic E coli infections in rabbits?
A
Sulfatrim or Baytril
21
Q
Obligate intracellular pathogen reported as a cause of enterocolitis in rabbits and in association with E. coli
A
Lawsonia intracellularis
22
Q
Cause of proliferative ileitis characterized by epithelial hyperplasia nad mucosal inflammation
A
Lawsonia intracellularis
23
Q
Disease in pigs and ferrets caused by this bacteria, which has similar signs as Lawsonia intracellularis
A
Desulfovibrio desulfuricans
24
Q
Antibiotics used to treat Lawsonia
A
Macrolides (tylocin, erythromycin, lincomycin) in non-rabbits.
Chloramphenicol BID x 7-14 days in rabbits.
25
What bacteria causes Tyzzer's disease
Clostridium piliforme
26
Clinical signs of Tyzzer's disease
watery diarrhea, depression, death.
27
Causes of Tyzzer's disease
Stress (overcrowding, unsanitary conditions, high temperatures, breeding)
28
Pathology findings of Tyzzer's disease
Characteristic foci of necrosis in the liver and degenerative lesions of the myocardium. Edematous intestinal wall.
29
What common cleaner kills Clostridial spores
0.3% sodium hypochlorite solution (bleach), or heating to 173 degrees F for 30 minutes.
30
What antibiotics are Campylobactor bacteria susceptible to?
Chloramphenicol.
| Resistant to fluoroquinolones and macrolides.
31
What virus (genus) causes rabbit hemorrhagic disease virus (RHDV)?
Lagovirus (genus)
| Caliciviridae (family)
32
How is RHDV spread?
urine, feces, respiratory via direct contact, with carcasses, or fur from affected rabbits, or contact with fomites (water, feed, utensils, clothing, cages), and flies, and insects are vectors.
33
What pathologic signs are seen with RHDV?
Severe hepatic necrosis and death from DIC. Splenomegaly (dark and thickened). Congestion and hemorrhage of the lungs. Pale, reticulated pattern in liver.
34
Hematology or RHDV
lymphopenia and gradual thrombocyotpenia. prolonged PT and APTT times.
35
Clinical signs of RHDV
May also cause febrile, lethargic, anorexic, constipated, or diarrhea signs. Tachypnea, cyanosis, foamy nasal discharge.
36
RHDV2 major capsid protein
VP60
37
Clinical signs of rabbit coronavirus and diagnosis
lethargy, diarrhea, abdominal swelling, death.
Pleural effusion and cardiomyopathy. High mortality within 24 hours.
The virus causes hemagglutination in feces- needed for dx.
38
Common age of coronavirus outbreaks
3-10 weeks old, but also found in clinically normal adults.
39
Rotavirus attacks which portions of intestine
Differentiated enterocytes lining tips of villi in jejunum and ileum
Affects infant rabbits.
40
Human enzyme-linked immunosorbent assay test kits will detect rotavirus group A in rabbits: T of F
True
41
Pathology findings of rotavirus
severe billus blunting, villus fusion, and submucosal edema of small intestines, and fluid cecal contents
42
Eimeria stiedae infects what organ of the rabbit
Liver. The rest are in the intestines
43
Cause of hepatic coccidiosis
Eimeria stiedae
44
Most common intestinal coccidia
Eimeria perforans #1.
| E. magna, E media, E irresidua.
45
Cecotrophs eaten from anus can spread coccidia: T or F
False
46
Treatment for coccidiosis
sulfadimethoxine for 7 days, amprolium in drinking water. Treatment is to limit multiplication until immunity develops.
47
Cause of discrete and transitory diarrhea in young rabits peaking at 30-40 day ages
Cryptosporidium parvum- no effective treatment
48
Nonpathogenic flaggelates and locations in rabbits
Giardia duodenalis (anterior region of small intestine)
Monocercomonas cuniculi and Retortamonas cunicula (cecum)
Entamoeba cuniculi (cecum and colon)
Large ciliated protozoa such as those of the genus Isotricha in ruminants
49
Common pinworm of rabbits
Passalurus ambiguus (cecum and colon). Nonpathogenic.
Via ingestion cecotrophs.
Treatment: Thiabendazole q 10-14 days
50
Gastrointestinal neoplasia of rabbits and location
Stomach (leiomyoscarcoma and adenocarcinoma)
Intestine (leiomyomaand leiomyosarcoma)
Sacculus rotundus and rectal squamous columnar junction (papilloma)
Bile duct (adenoma and carcinoma)
Metastatic uterine adenocarcinoma
51
Most common liver lobe to torse.
Caudate lobe #1
| Right lobe, quadrate an dposterile lobule of left lobe also possible.
52
Two common aflatoxins
Aspergillus flavus and A parasiticus.
| Rabbits have lowest LD50.
53
Pathology findings of aflatoxin ingestion
Death 3-4 days.
| COngested and icteric livers, and distended gall bladder with inspissated bile.
54
Pneumonia is generalized in rabbit due to the lack of septa to divide the lungs into lobules: T or F
True
55
Rabbits are a common research model for rhinitis and sinusitis: T or F
True
56
What bacteria causes crusting of the mucocutaneous borders of the nose, lips, and eyelids. Crusting of nares.
T. cuniculi (rabbit syphilis) is not a primary respiratory pathogen.
Treat once weekly with procaine/benzathine penicillin for 3 weeks.
57
Cause of nasal granulomas in rabbits
Mycobacterium spp
58
Bacteria commonly isolated for rabbits with pyometra or metritis
P multocida and S aureus
59
Cylindrical blood clots molded with uterine horns indicate which condition
Endometrial Venous Aneurysms
60
Bacterial cause of late term (>21d) abortions
Listeria spp.
61
Abortion with fetal resorption can be induced by administering this drug once daily on days 15 and 16 after mating
aglepristone
62
Bacterial cause of epididymitis or orchitis
P multocida.
63
Cause of vesicle formation, ulcerations and scabs on vents.
T. paraluiscuniculi (rabbit syphilis or vent disease)
64
Treatment of T paraluiscuniculi
Parenteral (never oral) Pen G IM SID x 5-7d
65
Intestinal calcium absorption is independent of Vit D3 levels in rabbits: T or F
True
66
Sedative drug that relaxes urethral sphincter
Midazolam
67
What is Masugi nephritis?
Inflammatory nephritis induced by continuous immunization with large doses of antigen.
68
Treatment for Masugi neprhitis
Tea polyphenols
69
When rabbits ar eplaced on a low-calium, high-phosphorous diet, uremic rabbits (renal failure) will develop what condition?
Secondary hyperparathyroidism
70
What low level of Vit D may cause toxicity?
5x normal
71
Hypervitaminosis D causes what clinical signs
In weeks to months- mineral deposition in tissues, aorta, kidneys.
Kidneys multifocal, tan-gray throughout cortices.
72
What vitamin protects kidneys during aminoglycocide therapy
Vit B6
73
Tiletamine in Telazol causes what condition?
Nephrotoxicity- nephrosis at low doses and severe irreversible nephrosis at high doses.
74
Long term NSAIDs (diclofenac) causes what condition?
Significant ultrastructural renal alterations, increased renal artery vasoconstrictor activity
75
What breed of rabbits has a high incidence of autosomal rescessive mutations leading to renal agenesis (only 1 kidney)?
Havana breed
| In males, the ipsilateral testicle is often missing
76
What condition causes nonsuppurative, granulomatous nephritis?
Encephalitozoonosis (nosematosis) by E. cuniculi
77
E cuniculi spores have a predilection for which tissues?
kidneys (31 days), brain, spinal tissue
78
How long are E cuniculi spores excreted in the urine
up to 3 months
79
How often is diethylstilbestrol given to spayed females in hormone-responsive urinary incontinence
1-2x weekly PO
80
What does the IRE (isolated rabbit eye) test?
irritation or corrosion to teh corneal surface by scoring swelling and corneal opaicity, and area of corneal involvement + fluoroscein penetration.
81
What are the cons of IRE tests
Lack of tear film causes higher false positives
| Iridal damge from inflammatory or neuromusclar components cannot be assessed
82
What are cons of ICE (isolated chicken eye) test?
surfactants and alcohols results in false negative and false positives
83
When is BCOP (bovine corenal opacity and permeability) not acceptable?
When assessing mild irritancy. BCOP suitable for moderate, severe, and very severe eye irritants
84
Cons of ex vivo non-ocular organotypic models
Do not address conjunctival and iridial responses, inflammation and corneal recovery, or reversibility of lesions
85
What is the Anton test?
Used to identify Listeria monocytongenes; culture specimen is injected into rabbit conjunctiva to determine pathogenicity.
Anton discovered Listeria causes hemolysis in blood agar
86
Which rabbit is NOT a specific genetic model for atherosclerosis?
Saint Thomas Hospital Rabbit
Watanabe heritable hyperlipidemic rabbit
Flemish giant rabbit
Kurosawa-Kusanagi hypercholesterolemic rabbit
Flemish Giant
87
Why are Watanabe heritable hyperlipidemic rabbits (WHHR) used for atherosclerosis testing?
Analogous to human familial hypercholesterolemia due to genetic deficiency of LDL receptors
88
Vitamin A deficiency causes?
Hydrocephalus, cerebellar herniation in neonates
| Keratitis progresses to iridocyclitis in adults
89
What is palatochisis
Cleft Palate
90
Palatochisis commonly occurs with what conditions?
Spina bifida
Hydrocephalus
Dwarfism
(NOT Chordoma)
91
What compound topically induces sensitization and when applied to rectum causes ulcerative colitis
DNCB (Dinitrochlorobenzene)
92
WHHL model of atherosclerosis
Decreased LDL concentration in WHHL
| Hypercholesterolemia
93
KHC (Kusanagi Hypercholesterolemic) model of athersclerosis
```
Decreased HDL concentration in KHC
High serum cholesterol
High Triglycerides
High phospholipid
12 base pair deletion of LDL on mRNA
Hypercholesterolemia
High coronary xanthoma
```
94
What is the homozygous (partial dominant trait) Pelger-Huet anomaly?
IFailure of nuclei of neutrophils (an eos) to mature to normal segmented form. PHA occurs secondary to mutation in the lamin B receptor and a left shift always appears to be precent.
95
RITARD technique is used to produce a rabbit model of what human dz?
Campylobacter enteritis, E coli, and aeromonas origin
96
What does RITARD stand for?
Rabbit intestinatl tie-adult rabbit diarrhea
97
What drug induces acute respiratory distress syndrome?
Phorbol myristate acetate (given daily IV)
98
Osteopetrosis (os/os) occurs in what rabbit breed?
Autosomal recessive (os) Dutch Belted
99
Most common cause of clostridial enterotoxemia rabbits
Clostridum spiroforme
100
Congenital buphthalmia pressures are normal until what age?
3 mos
101
Name two genera pinworms found in rabbits
Passalurus ambiguus and Passalurus nonanulatus;
| Syphacia
102
Definitive host for taenia psiformis and taenia serialis?
Dogs
103
Monckeberg dz characterized by what?
medial calcific sclerosis/vessel hardening, where calcium deposits are found in the muscular middle layer of the walls of arteries
104
Rabbit ear mite
Psoroptes cuniculi
105
What separates the proximal and distal colon
Fusus coli
106
Normal finding with rabbit RBCs
anisocytosis
107
The Guide recommendation for rabbit room temperature
61-72 F
108
What makes the rabbit kidney unique?
The renal tubules can be separated from kidney slices with the basement membrane intact!
109
What enzyme do rabbits lack that is necessary for liquefying pus?
Myeloperoxidase in rabbit heterophils
110
Common bacterial cause of moist dermatitis
Pseudomonas aeruginosa
111
What type of pigment causes blue-green discoloration caused by P aeruginosa?
Pyocyanin pigment
112
The superficial digital flexor is kept under tension (T or F)
True
113
Bacterial cause of rabbit syphilis
Treponema paraluis cuniculi
114
Treponema paraluis cuniculi is transmitted by?
Sexual tranmission,
| direct contact, or contact of young with infected dam at birth
115
Rabbit syphilis is zoonotic. T or F
False
116
List the clinical signs of rabbit syphilis.
redness, swelling, and ulceration of skin around anogenital region. Then secondary scabs and ulcers around eyes and nose from cecotrophy and grooming.
117
Incubation period of rabbit syphilis
10-16 weeks
118
Serologic testing of rabbit syphilis must occur after 8-12 weeks. T or F
True
119
What is the treatment of rabbit syphilis
Benzathine penicillin G/procaine penicillin G SC q7 days for 3 weeks.
120
What causes the skin infection necrobacillosis?
Fusobacterium necrophorum (gram negative anaerobe)
121
How do rabbits develop necrobacillosis?
Fecal contamination of wounds.
122
Common dermatophytes of pet rabbits.
Microsporum canis or M. gypseum
123
Common dermatophytes of laboratory rabbits.
Trichophyton mentagrophytes
124
Common anatomical location for dermatophytosis
Nasal planum, eyelids, and pinnae. Then legs, feet, nailbeds. Erythema and dry, yellow crusting.
125
What is the only dermatophyte to fluoresce under a Wood's lamp?
M. canis
126
How to diagnose T. mentagrophytes?
indirect ELISA, dermatophyte culture,
127
What special stains are used to identify dermatophytes?
Periodic-acid Schiff, Gridley, or Gomori's methenamine silver stain
128
Common ear mite in rabbits
Psoroptes cuniculi
129
Lifecycle of psoroptes cuniculi
21-day cycle on animal, but can live weeks off host in normal environmental temperatures
130
Common early sign of ear mites in rabbits
Dry grayish-white tan crusty exudate
131
Common fur mite in rabbits
Cheyletiella parasitorvorax (non-burrowing)
132
Life cycle of Cheyletiella parasitorvorax
14-21 days. Eggs survive 10 days off host.
133
Chyletiella is zoonotic T or F
True
134
Skin biopsies if conducted on rabbits with chyletiella reveal what?
hyperkeratosis with mixed inflammatory cell infiltrate
135
Name a non-burrowing, non-pathogenic mite
Leporacarus (Listrophorus) gibbus
Brown in color, laterally compressed with short legs
Eggs smaller, stick more distally, less firmly attached than Cheyletiella.
136
Highly contagious burrowing mites in rabbits
Sarcoptes scabiei var. cuniculi (head, neck, trunk, genitalia) and Notoedres cati var. cuniculi (head only)
137
Clinical signs of burrowing mites
Yellow, crusty dermatitis
138
Thin, elongated mite, obligate host-specific parasite of rabbits
Demodex cuniculi
139
Blood-feeding ectoparasite where only protonymphs and adults found on host.
Ornithonyssus bacoti (tropical rat mite)
140
Common rabbit flea
Spilopsyllus cuniculi (rabbit flea) - affects face and ears
141
Eastern rabbit flea
Cediopsylla simplex
142
Giant eastern rabbit flea
Odontopsyllus multispinosus
143
Stick tight flea
Echidnophaga gallinacea
144
Fleas rabbits most commonly affected by:
```
Ctenocephalides felis (cat flea)
Ctenocephalides canis (dog flea)
Affects dorsum and tail
```
145
Disease fleas can transmit to rabbit
Myxoma virus
146
Sucking rabbit louse (lice)
Haemodipsus ventricuosus - Pediculosis
147
Disease lice can transmit to rabbit
Tularemia
148
Disease black flies (Simuliidae) can spread
Myxoma virus
149
Obligate secondary blowfly that lays eggs in wounds or body orifices of rabbits
Wohlfahrtia vigil (grey flesh fly)
150
Primary fly strike attracted to soiled skin
Calliphoridae
151
First stage larve that enter body through nasal or oral openings
Cuterebra
152
Rabbit pinworm
Passalurus ambiguus (oxyuriasis) - nonpathogenic
153
Rabbit tapeworm
Rabbits are intermediate host- causes 4-5cm cyst (coenurus) in connective tissue
154
Sylvilagus spp rabbits do not develop systemic disease of myxoma visurs. T or F
True
155
Sylvilagus brasiliensis
Jungle rabbit
156
Sylvilagus bachmanni
Brush rabbit
157
Myxomatosis incubation
8-21 days
158
Causes of myxomatosis
biting arthropods or direct contact (uncommon)
159
Clinical signs of myxomatosis (poxvirus)
Swollen eyelids and ear margins, genital swelling, ocular discharge and peri-ocular edema, skin nodules up to 1cm, and death from septicemia in 10-14 days. Acute death can occur in 5-7. No treatment
160
Shope fibroma affects which species of rabbit
Sylvilagus - fibromas occur on feet, legs, and offasionally face and back and regress over time.
161
Shope papilloma virus is caused by?
biting insects.
162
Shope pappilloma virus experimentally causes what in Oryctolagus species?
malignant transformation to squamous cell carcinoma.
163
Oral papillomavirus undergoes carcinomatous transformation. T or F
False
164
What immunoreaction causes sebaceous adenitis
T-cell-mediated autoimmune rxn at sebaceous glands and hair follicles.
165
Sebaceous adenitis has been linked to what condition in rabbits
Thymoma and autimmune hepatitis
166
Clinical signs of sebaceous adenitis
nonpruritic, chronic exfoliative dermatitis. Hair epilaes easily with keratin debris around hair shaft (follicular casts)
167
What is used to treat sebaceous adenitis?
cyclosporine and miglyol
168
What condition causes joint laxity, skin hyperextensibility, and skin fragility
Ehlers-Danlos-like syndrome (cutaneous asthenia)
169
Most common disease affecting the external pinna
ear mites (P. cuniculi)
170
Microsporidium, obligate intraceullar pathogen
Encephalitozoan cuniculi
171
Clinical signs of E cuniculi
head tilt, nystagmus, ataxia, circling, rolling (vestibular disease)
172
Components of E cuniculi spore
Polar filament, nucleus, electron-dense sporoplasm
| Spore wall, endospore, and plasma membrane
173
Rabbits suffering from otitis interna may have signs of upper respiratory disease. T or F
True
174
What neurologic condition may cause unilateral facial spasm or hemifacial dysfunction
Upper respiratory infection (not E. cuniculi)
175
Portion of the brain most affected by E cuniculi
Cerebrum, followed by leptomeninges
176
What stain is more sensitive at detecting E cuniculi spores than acid fast trichrome stain?
Ziehl-Neelsen stain
177
Serologic testing is a means for monitoring E cuniculi infection in rabbits. T or F
True
178
What immunoglobulin is used for determining early disease of E cuniculi (prior to day 35)?
IgM
179
Treatment for E cuniculi in rabbits
Fenbendazole 20 mg/kg PO SID for 28 days.
180
Side effect of Benzimidazoles?
Bone marrow aplasia and intestinal tract crypt epithelial necrosis.
181
What parasite causes malacic tracks in affected CNS tissue
Baylisascaris species
182
What condition causes granulomatous meningoencephalitis, but also tachyzoits in multiple organs?
Toxoplasmosis
183
Treatment of toxoplasmosis in rabbits should be clindamycin (like cats). T or F
False
184
Treatment of toxoplasmosis in rabbits
Pyrimethamine, Bactrim, or doxycycline
185
What toxicosis causes CNS edema, blindness, and anemia
Lead
186
What is used to treat lead toxicosis
Calcium disodium ethyleneiamine tetraacetate (chelation)
187
What vitamin deficiency causes muscular dystropphy and degeneration of skeletal muscle myofibers causes paresis.
Hypovitaminosis E
188
Old feed will become deficient in what vitamin
Vitamin E
189
What vitamin deficiency causes hydrocephalus with stenosis of cerebral aqueduct leading to increased CNS pressure
Hypovitaminosis A
190
Excess of this vitamin causes resorption of bones and calcification of soft tissues, such as the aorta
Vitamin D
191
What vitamin deficiency causes ataxia, paralysis, and death
Hypovitaminosis D
192
What vitamin deficiency causes enlarged joints, crooked legs, arched backs, and enlarged rib costochondral junctions
Hypocalcemia or Hypovitaminosis D.
193
What vitamin deficiency causes poor bone consistency leading to brittle bones and limb problems
Manganese
194
What vitamin deficiency causes seizures
Magnesium
195
What vitamin deficiency causes muscle weakness and paralysis
Potassium
196
What is the most common cause of CNS neoplasia in rabbits
Lymphoma
197
How many valves are in the rabbit triscupid valve
2
198
The aortic nerve is associated with chemoreceptors. T or F
False. (Baroreceptors)
199
The pulmonary artery is poorly muscular. T or F
False - heavily muscular
200
The rabbit has a persistent left cranial vena cava that drains into the coronary sinus. T or F
True
201
What settings should be used for rabbit ECGs
vertical calibration: 2cm/mV
| horizontal paper speed of 40 mm/s.
202
Rabbits have a normal respiratory sinus arrhythmia. T or F
False
203
What is the systolic blood pressure of rabbits
120-180 mmHg
204
What is the most common type of lymphoma
B-cell
205
Thymic lymphoma is what origin
T-cell
206
What is the most common cutaneous neoplasm in rabbits
Trichoblastomas basal cell tumors)
207
Recommended room temperature for rabbits
61-72 F (16-22 C)
208
Rabbits <2kg require what housing dimensions
1.5 ft2 x 16"
209
Rabbits up to 4kg require what housing dimensions
3.0 ft2 x 16"
210
Rabbits >5.4kg require what housing dimensions
>5 ft2 x 16"
211
Rabbits up to 5.4kg require what housing dimensions
4 ft2 x 16"
212
What does it mean to have a merangiotic fundus?
Vessels run horizontally.
213
Common bacterial cause of conjunctivitis, epiphora, nasolacrimal duct obstruction, and dacryocystitis
P multocida
214
Spontaneous development of corneal dystrophy (accumulation of cholesterol or lipid crystals in cornea) occurs in which breed?
American Dutch belted rabbits
215
Name the breed of rabbits with heritable hypercholesterolemia which causes yellow-white granules to develop along corneal-scleral junction and the iris.
Watanabe rabbits
216
What condition causes phacooclastic uveitis (and cataract), often seen in young or dwarf rabbits?
E cuniculi (granulomatrous encephalitis and renal lesions too)
217
What bacteria can cause abscess of the iris?
P multocida
218
Keratitis of the cornea can be caused by which condition?
Shope fibroma virus
219
What is the mode of inheritance for congenital glaucoma?
Autosomal recessive
220
Treatment of buphthalmos?
Dorzolomide or Timolol maleate
221
Laser cycloablation can be used in albino rabbits. T or F
False, only pigmented rabbits
222
What is the name of the deep gland to the third eyelid?
Harderian gland (two lobes- dorsal white and ventral pink)
223
The laboratory rabbit belongs to what family?
Leporidae
224
What is the muscular architecture of the rabbit esophagus?
3 layers, all striated
225
The capacity of the rabbit cecum is what percent of the total digestive tract capacity?
40%
226
Volume of bile a rabbit produces per day
~250ml (~100-150 ml/kg)
227
Describe the right AV valve in the normal rabbit heart.
Two cusps, one large, one small
228
Rabbit skeleton is what percent of body weight?
8%
229
Neonatal rabbit is ectothermic until what age?
7 days
230
Architecture of reproductive tract of rabbits?
2 cervix, 2 uterine horns
231
Which of the following condition is not associated with a cleft palate? Spina bifida, Chordoma, Hydrocephalus, Dwarfism
Chordoma
232
What compound is applied topically to induce sensitization and subsequently applied of rectum of rabbit model for ulcerative colitis?
Dinitrochlorobenzene (DNCB)
233
The Pelger-Huet anomaly affects what blood component of rabbits?
Heterophils
234
The development of B-cell leukemias in rabbits with the E mu-myc transgene contrasts with the development of B-cell lymphomas in mice carrying a similar transgene. T or F
True
235
The RITARD technique is used to produce a rabbit model of what human disease?
Campylobacter enteritis
236
Daily intravenous injection of phorbol myristate acetate induced what model?
Acute respiratory distress syndrome
237
Osteopetrosis (os/os) occurs in rabbits of what strain?
Dutch belted
238
```
What test is not an alternative to the Draize test of ocular toxicity?
Sperm motility
Limus amebocyte lysate assay
Water flea assay
Tetrahymena thermophila assay
Chorioallantoic membrane assay
```
Limus amebocyte lysate assay
239
Name the rabbit ear mite
Psoroptes cuniculi
240
What is considered normal for rabbit red blood cells?
Anisocytosis
241
Guide recommendation for rabbit room temps
61-72
