radiology of lung cancer (diagnosis and staging) Flashcards

(52 cards)

1
Q

steps of systematic review of CXR

A

name, marker, rotation, penetration

lines, metal work

heart

mediastinum

lungs - upper, middle and lower zones

bones

diaphragm

soft tissues

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2
Q

where do the lungs sit in relation to the diaphragm

A

they sit in front and behind the diaphragm and hemi-diaphragm?

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3
Q

review of mediastinum on CXR

A

hilar vascular structures should be crisply defined, compare height and difference between L and R

no widening of mediastinum

trachea should be central

look behind the heart

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4
Q

review of lungs on CXR

A

compare upper, mid and lower zones

look between ribs for lung detail

remeber to look behind the heart

compare L and R

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5
Q

what is the abnormality in this CXR

A

mass in the R lung

possible cavity of infection

  • peripheral lung carcinoma
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6
Q

what is the abnormality in this CXR

A

whiteout of the L semi thorax

could be - total collapse of the lung, pneumonectomy, large pleural effusion

  • central lung carcinoma which has lead to collapse, potential effusion also

if there is a concern about a central tumour which has caused collapse, a chest and abdominal CT would be done

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7
Q

what is the abnormality in this CXR

A

right upper lobe collapse

movement of the hilum

hyper-inflation of the lung - darker colour

BEWARE the lobar collapse which fails to resolve in 2-3wks in a smoker of age>45

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8
Q

what would be seen on a CXR if the lower of middle lobe collapses

A

lower - double heart border (triangle on both sides)

middle - loss of clear heart border

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9
Q

features of lung cancer on CXR

A

lesions often more subtle

beware of lesions behind the heart and hila

compare with previous films and always look at review areas

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10
Q

what are the review areas on a CXR

A

hila

lung apices

behind the heart

behind the diaphragm

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11
Q

what is the abnormality in this CXR

A

left middle zone abnormality

abnormality of the hilum - bulky

left hilar mass

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12
Q

what is the abnormality on this CXR

A

abnormality on the R

normal hilum position

rounded structure which is denser than the other side

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13
Q

what is the abnormality on this CXR

A

left lower zone abnormality

opacity behind the heart

cardiac area should be homogenous in density

mass behind the heart

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14
Q

what is the abnormality on this CXR

A

mass left costophrenic angle

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15
Q

what is the abnormality on this CXR

A

much denser on the R around apex

right apical/pancoast tumour

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16
Q

what is the abnormality on this CXR

A

tumour on R base

lacy like obacity (fibrosis) predominant in mid/lower zones and peripheries

clinical hx: increasing SOB in smoker, hx of pulmonary fibrosis, recent haemoptysis

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17
Q

what are the steps to take following a mass on CXR

A

always compare with previous imaging

confirm lesion is intrapulmonary

CT: evaluate size, shape, atelectasis, border, density, solid/non-solid, dynamic contrast enhancement >25 HU, growth

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18
Q

what is the abnormality on this CXR

A

rounded uniform opacity

previous breast cancer, mastectomy and then implant

look for evidence of metastasis

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19
Q

define pulmonary mass

A

an opacity in lung >3cm with no mediastinal adenopathy or atelectasis

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20
Q

define pulmonary nodule

A

opacity in lung up to 3cm with no mediastinal adenopathy or atelectasis

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21
Q

potential diagnosis for solitary pulmonary nodule or mass

A

lung cancer (age, smoking hx)

metastasis (prev hx of breast, renal, seminoma, sarcoma)

benign lung neoplasm e.g. carcinoid, hamartoma

infection (bacterial, TB, fungal)

vascular haematoma, AVM

multiple nodules/masses are much more likely to be mets

22
Q

if an opacity is longstanding and unchanging is it likley to be malignant?

A

much less likely to be malignant

take note of clinical hx and compare to prev films

23
Q

changes to lungs from TB

A

generally leads to scarring and calcifications in the upper zones

hila can be pulled up as a result of scarring

increased density can be a sign of infection

24
Q

steps for staging lung cancer

A

clincal hx/examination

performance status

pulmonary function

TNM international system for staging lung cancer - tumour, nodes, mets, higher stage = poorer prognosis

25
TNM staging
T = how big is it, how far has it spread, is it infiltrating any additional structures (T1-4) N = have cancer cells spread into the lymph nodes (N1-3) M - whether the tumour has spread anywhere else in the body (M1A-C)
26
how is the T in TNM staged
CT, PET, bronchoscopy
27
how is the N in TNM staged
PET, mediastinoscopy (confirms malignancy in nodes), CT, EBUS/EUS CT isn't as useful for notes PET will show the metabolic activity - useful for small nodes
28
how is the M in TNM staged
PET, CT, bone scan
29
FDG PET scan
functional imaging used in lung cancer staging labelled glucose analogue expensive limited availability in UK
30
PET scan
metabolic hot spots are matched to anatomical location very metabolically active areas aren't necessarily cancer, can also be infection
31
Tx/T0/Tis
Tx = 1y tumour cannot be assessed T0 = no evidence of 1y tumour Tis = carcinoma in situ
32
T1
tumous = 3cm in greatest dimension surrounded by lung or visceral pleura without bronchoscopic evidence of involvement of the main bronchus T1a - minimally invasive adenocarcinoma tumous, = 1cm in greatest dimesion T1b - = 2cm T1c - = 3cm
33
T2
tumour \>3cm but \<5cm or tumour with any of the following features: (T2 tumours with these features are classified T2a if = 5cm) - involves main bronchus but not carina - invades visceral pleura - associated with atelectasis or obstructive pneumonitis that extends to hilar region involving part or all of the lung T2a - \>3cm but \<4cm in greatest dimension T2b - \>4cm but \<5cm in greatest dimension
34
T3
tumour \>5cm but \<7cm or one that directly invades any of the following: - chest wall (including superior sulcus tumours) - phrenic nerve - parietal pericardium or separate tumour nodule(s) in the same lobe as the 1y
35
T4
tumour \>7cm or invades any of the following: - diaphragm - mediastinum - heart - great vessels - trachea - recurrent laryngeal nerve - oesophagus - vertebral body - carina separate tumour nodule(s) in a different ipsilateral lobe
36
how is PET/CT used in T staging
assessing chest wall or mediastinal invasion
37
N0
no regional lymph node metastasis
38
N1
ipsilateral peribronchal, hilar or intrapulmonary nodes including by direct extension
39
N2
ipsilateral mediastinal, subcarinal
40
N3
contralateral mediastinal, contralateral, hilar, scalene or supraclavicular
41
what proportion of patients present with mets
1/3
42
what are the scommon sites of mets in lung cancer
cerebral skeletal adrenal liver
43
M0
no distant mets
44
M1 - distant mets M1a (metastatic disease in thorax): separate tumour nodule(s) in a contralateral lobe tumour with pleural or pericardial nodules or malignant pleural or pericardial effusion M1b - single distant mets M1c - multiple distant mets
45
PET/CT in staging
performs whole body staging in a single study excluding cerebral disease (brain is normally metabolically active) discloses mets and other pathology not deteceted by other means (unexpected mets in 10-20%) excludes mets where structural imaging abnormal non-invasive
46
how should cerebral disease be investigated
head CT w/ contrast
47
limitations of PET CT
all tests have false -ve and +ve results cost
48
stage I cancer
T1 N0 M0 T2 N0 M0
49
stage II cancer
T1 N1 M0 T2 N1 M0 T3 N0 M0
50
Stage III cancer
T3 N1 M0 T3 N2 M0 T4 N0-2 M0 T1-4 N3 M0
51
Stage IV cancer
any T any N M1 1% 5YS
52
Tissue diagnosis
bronchoscopy and EBUS percutaneous image guided biopsy,CT/US guided mediastinoscopy - sample mediastinal nodes mediastinotomy for anterior mediastinal nodes VATS explorative thoracotomy