Random Exam 2 Questions Flashcards by Chris Bessette

T/F: Infectious laryngotracheitis infects turkeys

False

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T/F: Foals infected with EHV-1 present with interstitial pneumonia systemic disease and high case fatality rate

True

Equine Abortion Virus

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T/F: Most EHV-1 abortions usually occur between 3-5 months of gestation in mares

False

Occur in last trimester (between 8th & 10th month)

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What is the incubation period for pseudorabies in swine?

~30 hours

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T/F: Pseudorabies in adult pigs is characterized by intense pruritis, ganglioneuritis, and high mortality rate

False

Pigs don’t get pruritus with pseudorabies, only secondary hosts

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T/F: Valtrex cannot be used to treat a herpesvirus infection caused by a herpesvirus with mutation in its thymidine kinase gene

True

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T/F: Mortality in chickens presenting with infectious laryngotracheitis is usually due to occlusion of the trachea by a caseous plug.

True

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T/F: A characteristic of infectious bovine rhinotracheitis is that the severity of the respiratory form is largely determined by the extent of secondary bacterial infection.

True

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T/F: The hemadsorption-inhibition assay is always carried out using virus infected cell culture.

True

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T/F: Keratitis describes inflammation of the keratin layer of the epidermis

False

Inflammation of the cornea

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T/F: Papillomavirus infections are characterized by proliferative growth of infected cells.

True

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T/F: Two forms of fowlpox have been described in chickens; a cutaneous form and a diphtheritic form

True

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T/F: Newborn puppies infected with canine parvovirus may manifest myocarditis and cerebellar hypoplasia

False

No cerebellar hypoplasia

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T/F: Fowlpox is mechanically transmitted by mosquitoes and lice

True

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T/F: Azidothymidine [AZT], an antiviral drug, inhibits replication of feline immunodeficiency virus by inactivating the viral enzyme that cleaves polyproteins into functional proteins.

True

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T/F: Porcine parvovirus infection in pigs is a persistent infection that results in continuous contamination of the environment

True

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T/F: Infectious bovine rhinotracheitis is also referred to as “red nose”

True

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T/F: Hemorrhagic disease of puppies is also known as “fading puppy syndrome”

True

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T/F: Mortality in the wet form of fowlpox is due to asphyxiation brought on by occlusion of the larynx

True

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T/F: Milker’s nodule is a condition observed in persons infected with the virus that causes pseudorabies

False

Pseudocowpox, not pseudorabies

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T/F: African swine fever is exotic in the United States

True

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T/F: Alphaherpesviruses multiply optimally at low body temperature, establish latent infections in nerve ganglia, and infected cells show cytomegaly

False

no cytomegaly

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T/F: Poxviruses that belong to the same genus usually show antigenic cross-reactivity.

True

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T/F: Canine parvovirus diarrhea results from virus replication in the mature enterocytes of the intestinal tract

False

Immature enterocytes

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T/F: In contrast to parvoviruses that infect other domestic species, porcine parvovirus tends to cause persistent infections with chronic shedding of the virus

True

T/F: In North America, sheep are the main reservoirs in the transmission of malignant catarrhal fever

True

T/F: A carrier animal sheds virus only intermittently

False Could be continuous or intermittent

T/F: Papillomavirus infection of the skin begins with virus multiplication in the keratinized layer of the epidermis

True

T/F: Type I and II interferons enhance cellular expression of MHC class I proteins.

True

T/F: Viruses are readily demonstrated using bright-field light microscopy

False

T/F: African swine fever is mechanically transmitted by soft ticks

False [Biological, not mechanical]

T/F: Aplastic anemia in chickens due to Chicken Infectious Anemia is caused by direct infection of the RBC precursor stem cells

True

T/F: Canine parvovirus is a mutant strain of feline parvovirus

False

T/F: Persitent infection with intermittent or continuous viral shedding occurs in all herpesvirus infections

False Some are just localized inflammation reactions

T/F: Herpesviruses that lack the thymidine kinase gene are resistant to the antiviral drug acyclovir

True

T/F: Infectious laryngotracheitits has not been reported in turkeys

True

T/F: Recovered adult pigs serve as the main reservoirs of the virus that causes pseudorabies

True

T/F: Cross neutralization and cross protection occur among the subgroups of feline leukemia virus

False Subgroup specific

T/F: Feline parvovirus is antigenically related to canine parvovirus 2

True

The Coggins test is used in detecting horses with:

Equine infectious anemia

An incorrect statement concerning equine infectious anemia is * The virus is transmitted by blood-sucking insects * Preventative measures include vaccination * The virus may cross the placenta and infect the fetus * Animals that survive infection serve as carriers throughout their lives

Preventative measures include vaccination

Each disease is paired with a host. Which pair is mismatched? * Cowpox - cat * Postweaning multisystemic wasting syndrome - cattle * Infectious laryngotracheitis- c hicken * Pseudorabies - horse

Postweaning multisystemic wasting syndrome is in PIGS

Encephalitis is one of the manifestations of the diseases listed below except * Goatpox * Equine herpesvirus-1 disease * Infectious canine hepatitis * Pseudorabies

Goatpox

Viremia is a hallmark of which poxvirus disease? * Sheeppox * Pseudocowpox * Contagious ecthyma * Fowlpox

Sheeppox

Each disease is paired with a reservoir. Which pair is mismatched? * Cowpox - rodent * Pseudorabies - cattle * Feline rhinotracheitis - cat * Malignant catarrhal fever - wildebeest

Pseudorabies is in **pigs**, not cattle

In North America, which disease is NOT a reportable disease? * Pseudorabies * Sheeppox * Pseudocowpox * African Swine Fever

Pseudocowpox

Regarding pseudorabies, which statement is inaccurate? * Infected swine usually present with severe pruritus * The disease in invariably fatal in dogs, cats and cattle. * The disease is caused by a virus generally regarded as fragile * Mortality is due to respiratory failure.

Infected swine usually present with severe pruritus ## Footnote **\*\*\*Only secondary hosts have intense pruritus\*\*\***

Which of the following pairs is mismatched? * Adenovirus - carrier state * Inclusion body rhinitis - cytomegaly * Ulcerative dermatosis - venereal transmission * Cowpox - milker’s nodule

Milker's nodule is caused by **pseudocowpox**, not cowpox

Humans are susceptible to which disease? * African swine fever * Contagious ecthyma * Pseudorabies * Feline immunodeficiency disease

Contagious ecthyma

Each disease is matched with a host. Which is mismatched? * SMEDI - horses * Pseudorabies - cats * Infectious laryngotracheitis - chickens * Rubarth’s disease - dogs

SMEDI is in SWINE ONLY

A virus that cannot multiply in nondividing cells * Poxvirus * Parvovirus * Herpesvirus * Papillomavirus

Parvovirus

A virus that transforms T lymphocytes * Porcine cytomegalovirus * Porcine herpesvirus 1 * Gallid herpesvirus 2 * Feline herpesvirus 1

Gallid herpesvirus 2 Gallid herpesvirus 2 = Marek's disease

Which of the following conditions has NOT been associated with parvovirus infection in puppies? * Enteritis * Panleukopenia * Cerebellar hypoplasia * Myocarditis

Cerebellar hypoplasia | (only seen in kitty parvo)

Which virus is associated with equine sarcoids? * Bovine papillomavirus 1 * Bovine papillomavirus 3 * Bovine papillomavirus 5 * Bovine papillomavirus 4

Bovine papillomavirus 1

Which poxvirus disease is accompanied by a high mortality rate? * Ulcerative dermatosis * Contagious ecthyma * Lumpy skin disease * Sheeppox

Sheeppox

Concerning Marek’s disease, which statement is inaccurate? * Chickens and turkeys are the natural hosts for the virus * The most widely used vaccine for disease control consists of an avirulent turkey herpesvirus * Infection usually occurs via inhalation of dander from feather follicles * Enlarged nerves with loss of striations is one of the more consistant findings in affected birds

Chickens and turkeys are the natural hosts for the virus \*\*Not Turkeys!!\*\*

Which genus of Poxviridae produces a hemagglutinin?

orthopoxviruses

Which genus of Poxviridae does not replicate in embryonated eggs?

parapoxviruses

Inclusion bodies associated with Fowlpox are called:

Bollinger bodies

Alpha-herpesviruses grow more efficiently at higher body temperatures

No! Other way around, fool!

Abortions are commonly seen associated with the genital form of Infectious Bovine Rhinotracheitis

**False.** **Abortions are seen with the _respiratory form_, which is retarded**

Aujeszky's disease or "Mad Itch" are associated with which disease?

Pseudorabies

Which herpesvirus is associated with "abortion storm"?

Equine herpesvirus 1 (Equine Abortion Virus; EHV-1)

T/F: "Fading Puppy Syndrome" most commonly occurs in puppies 6 weeks and younger

False. "Fading Puppy Syndrome" (Hemorrhagic Disease of Puppies; Canine herpesvirus 1) most commonly occurs in puppies **_under 4 weeks of age_**

T/F: Abortions associated with Feline Rhinotracheitis are a result of viremia

False. There is no viremia with Feline Rhinotracheitis. Abortions are typically a result of persistent fever and dehydration

T/F: Most papillomaviruses are non-host specific

False

T/F: The antiviral drug Retrovir® is described as a prodrug and a nucleoside analog of thymidine triphosphate

True

Interferon-α and Interferon-β bind to the same cell surface receptor and also have identical functions

True

The synthetic herpesvirus prodrug acyclovir is an analog of *which DNA base*:

Guanosine

True or False: Parvoviruses contain double-stranded DNA, replicate in growing cells, and infect a narrow range of species

False Single-stranded DNA

True or False: Acyclovir requires the host-specified enzyme thymidine kinase to phosphorylate it to acyclovir monophosphate

False Thymidine kinase is a **herpesvirus-specified enzyme**, not a host-specified enzyme

Name three heavy metal salts utilized in negative staining electron microscopy:

1. Sodium phosphotungstate 2. Osmium tetroxide 3. Uranyl acetate

Most poxviruses are brick shaped. What is the exception to this rule?

Parapoxviruses are ovoid shaped

If, as scabs fall off of your cattle, you notice a dark red horseshoe-shaped ring of small scabs surrounding small, wart-like granulomas, what disease should be high on your differential list?

Pseudocowpox

Which form of sheeppox is more common in lambs and susceptible non-native breeds?

Malignant form

Which form of Fowlpow has higher mortality: the cutaneous form or diphtheritic form?

**Wet form [Diphtheritic form]** Death results from suffocation by occlusion of the larynx. Mortality can be up to 50%

What is the disease transmitted by Hematopinus suis?

Swinepox

T/F: Zovirax® is administered as a prodrug

True Zovirax is a trade name for Acyclovir, and is administered as a prodrug. Must be converted by three kinases

Cerebellar hypoplasia is characteristic of which disease? * A. Feline rhinotracheitis * B. Feline panleukopenia * C. Hemorrhagic disease of puppies * D. Pseudorabies

B. Feline panleukopenia

T/F: There is no vaccine for the very virulent plus form of Marek’s disease

True

T/F: Cattle have the cell-free virus in Malignant Catarrhal Fever

False Cattle have the **cell-associated virus**

Random Exam 2 Questions Flashcards

(81 cards)