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Flashcards in Random Final Exam Questions Deck (88)
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1

Measles virus is used to protect puppies against canine distemper. This is possible becasue of antigenic similarity of their:

fusion [F] protein

p 186

2

T/F: There is significant cross-protection among the different serotypes of Vesicular Stomatitis

False.

There are 2 serotypes and several subtypes of vesiculovirusThere is no cross-protection among the serotypes

p 168

3

The Coggins test is used in detecting horses with:

equine infectious anemia

p. 160

4

T/F: Adenoviridae virions agglutinate RBCs

True

p 141

5

Which species is known to be resistant to Infectious Canine Hepatitis, but susceptible to Canine Distemper?

Ferrets!

p 143

6

Corneal edema [blue eye] occurs in most cases of Infectious Canine Hepatitis [ICH]

False

Corneal edema occurs in about 20% of natural infections and less than 1% of dogs after vaccination

p 144

7

T/F: Most Infectious Canine Hepatitis infections are asymptomatic

True

p 144

8

Which breed is said to be especially susceptible to Equine Adenovirus Infection? Why?

Arabian Foals

Arabian foals are known to be very susceptible due to their combined T and B cell immunodeficiency

9

Describe the inclusion bodies associated with Retroviruses

There are no inclusion bodies. So you would just be explaining nothing.

What a waste of time.

10

T/F: Endogenous Retroviruses are pathogenic retroviruses that occur widely in the genome of vertebrates

False

Endogenous Retroviruses are non-pathogenic retroviruses that occur widely in the genome of vertebrates

p 148

11

Fading kitten syndrome is associated with viremic queens infected with:

feline leukemia virus

p 156

12

The ELISA test for feline leukemia detects the presence of:

circulating p27 antigen in plasma

p27 protein is the mjor feline leukemia virus [FeLV] group-specific antigen. It is produced within virus infected leukocytes and platelets

p 152, 156

13

Which porcine disease is commonly associated with splenic infarcts and button ulcers in the colon?

Hog cholera

p 226

14

T/F: The disease of Maedi/Visna has been reported in sheep, cattle and swine. 

False

Maedi/Visna is a disease of adult sheep and, to some extent, goats.

p 162

15

T/F: Incubation period of rabies is influenced by the distance the virus has to travel from its port of entry to the CNS.

True

p 167

16

T/F: A property of a virus belonging to the family paramyxoviridae is their ability to hemagglutinate RBCs in vitro.

True

p 178

17

T/F: Recovery from feline calicivirus infection is marked by intermittent shedding of virus for a period of time

True

p 240

18

T/F: A virus causing hog cholera can be identified in the lab using hemadsorption-inhibition assay

False

Diagnostic tests include virus isolation, antigen detection (FA or immunoperoxidase staining, ELISA), or serology

p 226

19

T/F: In feline immunodeficiency disease, the virus is shed mainly in saliva and principle mode of transmission is bites

True

p 157

20

T/F: Depopulation, a disease control measure, involves the culling of diseased animals only

False

Depopulation is the elimination of all susceptible hosts (infected, potentially infected, or contact animals) of a herd/flock or area basis

21

T/F: Regarding infectious canine hepatitis, the threshold antibody titer has been determined to be 1:100

False

1:500

22

T/F: Immunosuppression is a common sequela in diseases characterized by leukocytosis

False

Leukocytosis is a transient increase in the number of leukocytes in the blood

23

T/F: Antiretroviral protease inhibitors prevent the transcription of retroviral RNA into DNA genome

False

They inhibit viral proteases responsible for the cleavage of viral polyproteins into functional proteins by binding to their active sites

24

T/F: Corneal edema (blue eye), observed in some puppies presenting with infectious canine hepatitis, is an immune complex-mediated disease

True

25

T/F: Mammalian influenza virus is restricted to respiratory tract epithelial cells

True

26

T/F: BVD-MD is a cytopathic and non-cytopathic co-infection

True

27

T/F: Valtrex cannot be used to treat a herpesvirus infection caused by a herpesvirus with mutation in its thymidine kinase gene

True

Acyclovir requires the herpesvirus-specified enzyme, thymidine kinase, to phosphorylate it to acyclovir monophosphate.

p 76

28

T/F: Acute and convalescent serum samples for titration of antigen specific antibody titers are collected two to four weeks apart

True

29

T/F: After virus penetration into host cell, the parental RNA genome of a retrovirus is copied by reverse transcriptase into double-stranded DNA; this change in chromosome takes place in the nucleus of the host cell

False

Viral RNA is released into the cytoplasm.  Parental RNA is copied to ssDNA by reverse transcriptase.  ssDNA is made double-stranded, again by reverse transcriptase.  dsDNA moves into the nucleus

30

T/F: The hemadsorption-inhibiting assay is always carried out using virus-infected cell culture

True

p 88