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Flashcards in random medication information Deck (52):
1

what is topical capsaicin (Zostrix) ?

over-the-counter analgesic for minor pain

2

what herbal supplements increase risk of bleeding?

Gingko biloba
Garlic
Ginseng
Ginger
Feverfew

3

what drug is used to prevent seizures in pre-ecplampsia?

magnesium sulfate

4

what is a serious adverse effect of taking clozapine?

agranulocytosis
(therefore reserved for those with treatment resistant schizophrenia)

5

what is a definitive symptom of aspirin toxicity?

tinnitus

6

what is the antidote to benzodiazepines?

Flumazenil

7

what kind of drug is carbamazepine?

anti-epileptic, anti-seizure

8

what drug is used to treat extrapyramidal side effects?

benztropine (anticholinergic)

9

for what purpose do people take the supplement saw palmetto?

benign prostatic hyperplasia

10

major side effects of opioids

sedation, respiratory depression, hypotension, and constipation

11

what kind of drug is Levetiracetam (Keppra)?

anti-convulsant (seizure disorders)

12

side effects of sulfa drugs

Crystalluria (kidney injury) ; Photosensitivity; Folic acid deficiency (megaloblastic anemia and stomatitis) ; Rarely life-threatening agranulocytosis (leukopenia); Stevens-Johnson syndrome – stop the medicine if rash develops

13

Phenytoin therapeutic index

40-79 mcmol/L

14

Digoxin therapeutic index

0.6-2.6 nmol/L

15

Lithium therapeutic index

0.6-1.2 mmol/L

16

clinical presentation of lithium toxicity

primarily GI - persistent N and V, diarrhea
Later - neuro symptoms - tremor, confusion, ataxia, sluggishness

17

aminolycosides adverse effects

nephrotoxicity and ototoxicity

18

most common drugs that cause prolonged QT interval/increased risk of torsades to pointe?

haloperidol, methadone, ziprasidone, and erythromycin

19

which hypertension medications are teratogenic?

ACE inhibitors & ARBs

20

what is Riluzole?

only ALS drug; slows progression

21

what is a black box warning for celecoxib?

increased risk for cardiovascular complications

22

what is dicyclomine?

anticholingeric/antispasmodic to manage hypermotility in IBS

23

earliest sign of magnesium toxicity?

absent or decreased deep tendon relfexes (DTRs)

24

what blood level is magnesium toxicity?

> 3.5 mmol/L

25

after earliest sign of magnesium toxicity, what are other signs?

respiratory depression, oliguria, cardiac arrest

26

what is the antidote for magnesium sulfate?

calcium gluconate

27

why should potassium tablets be taken with a full glass of water and sitting upright after?

erosive, can cause esophagitis

28

anticholinergic side effects

pupillary dilation, dry mouth, urinary retention, constipation

29

based on anticholinergic side effects, what are conditions that are contraindicated to administration of anticholinergics?

closed-angle glaucoma, urinary retention, bowel ileus

30

what is the drug of choice to treat sinus bradycardia?

atropine (anticholingeric)
blocks parasympathetic vagal stimulation

31

what is the maximum hourly rate you can infuse potassium chloride peripherally and centrally?

10 mmol/hr peripherally
40 mmol/hr centrally

32

therapeutic index theophylline?

55-110 mcmol/L

33

first line treatment of torsades de pointes?

magnesium IV

34

significant adverse effect of oxytocin?

water intoxication

35

what class and what indications for amitriptyline?

trycyclic antidepressant, depression and neuropathic pain

36

what's the generic name of Reactin and what type of drug?

cetirizine

37

which antihistamines are non-drowsy?

fenofexadine and loratidine

38

what is dabigatran?

thrombin inhibitor; used to prevent thrombotic events

39

what is the max concentration of potassium that should be given?

40 mmol

40

what is Amphotericin B

systemic antifungal

41

which drugs can increase risk for lithium toxicity?

thiazide diuretics, NSAIDs, and antidepressants

42

what drugs will trigger malignant hyperthermia?

general anesthetics and succinylcholine

43

what is the drug that will be used to treat malignant hyperthermia?

dantrolene

44

what do you have to watch for with non-selective MAO Inhbitors?

tyramine containing foods because these drugs inhibit its breakdown which can cause hypertensive crisis

45

tyramine containing foods

Aged cheese, yeast, red wine, sauerkraut, cured meat, soy sauce

46

what drugs are used in bipolar?

mood stabilizers (lithium)
atypical antipsychotics (acute mania and long term mood stabilization)
antidepressants during depressive episode

47

what is buspirone used for?

anxiety

48

which type of antidepressants are most common for anxiety?

SSRIs

49

what is serum sickness?

similar to allergic reaction but happens 7-21 days after antibiotic exposure

50

what;s the generic name of Claritin?

loratidine

51

whats the generic name of Allegra?

fenofexadine

52

what kind of drug is chlorpheniramine?

antihistamine