Random Test 1 Stuff Flashcards

(31 cards)

1
Q

Cerebral arterial circle is formed by which arteries

A

Basilar and L/R Internal carotids

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2
Q

Main supply to cerebral hemispheres

A

middle cerebral artery

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3
Q

Main venous drainage from brain

A

Dorsal saggital sinus

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4
Q

Blood supply to spine in 1) cervical region 2) Thoracic region 3) lumbar region

A

1) Vertebral Arteries
2) Intercostal arteries
3) lumbar arteries

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5
Q

Blood supply to spine? Which is landmark?

A

Dorsal and ventral spinal arteries

*Ventral Spinal artery=landmark

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6
Q

Which two arteries make up basilar artery?

A

Ventral Spinal and Vertebral

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7
Q

3 Structures of Blood Brain Barrier

A

1) Endothelial Tight Junctions
2) Astrocyte processes
3) Non-fenestrated capillaries

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8
Q

3 Circumventricular organs

A

1) Median eminence
2) area postrema
3) pineal gland

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9
Q

Flow of CSF

A

Lateral ventricles–> interventricular foramen–> 3rd ventricle–> mesencephalic aqeuduct–> 4th Ventricle–> Subarachnoid and/or central canal of spinal cord

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10
Q

Places to collect CSF

A

1) Cisterna magna

2) Lumbo-sacral junction

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11
Q

Term for areas that produce CSF

A

Choroid Plexus

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12
Q

3 Types of neurons

A

1) Projection
2) Commissural
3) Associative

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13
Q

3 ways neurotransmitters are cleared from synapse

A

1) enzyme degradation
2) reuptake into axon terminal or glial cells
3) diffuses away

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14
Q

Precursor molecules for Acetylcholine

A

Acetyl CoA & Choline

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15
Q

Two things that can interfere with ACh release…and their result?

A

Botulism and tick paralysis…

Flaccid paralysis

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16
Q

Two receptor types for ACh

A

Nicotinic (ligand-gated)

Muscarinic (G protein coupled)

17
Q

Which enzyme degrades ACh? Which prevents it?

A

Degrades: Acetylcholinesterase
Prevents: Cholinesterase inhibitors

18
Q

Two categories of Monoamines and which NT fall under which

A

Catecholamines– NE, dopamine

Indolamines– Seratonin

19
Q

Precursor molecule for monoamines

20
Q

Which enzymes degrade monoamines? Inhibits?

A
Monoamine oxidases (MAO)
Monoamine oxidase inhibitors
21
Q

Dopamine functions

A

control of movement, emotion, motivation, stimulates hormone release from pituitary

22
Q

Seratonin functions

A

mood, memory, sleep, cognition, depression

23
Q

Categories of Amino acid NTs…which fall where?

A

Excitatory (Glutamate) & Inhibitory (GABA, Glycine)

24
Q

Which NT plays an important role in seizures?

25
How is glutamate cleared from synapse?
via astrocytes...recycled back to axon terminal as glutamine
26
Glutamate receptor activation
Ionotropic... non-NMDA binds glutamate, Na influx, slight depolarization; Mg removed from from NMDA receptor--activated.. Ca influx--NT release
27
Functions of GABA
inhibitory NT; induction of sleep, seizure suppressioin
28
GABA receptor action
ligand-gated; opens choloride ion channels to hyperpolarize cells
29
Major inhibitory NT in spinal cord
Glycine
30
Glycine receptor action
similar to GABA; ligand-gated; opens chloride channels to hyperpolarize cells
31
Two clinical conditions that affect Glycine
1) Tetanus--affects glycine release | 2) Strychnine toxin--block receptor