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Flashcards in Rational Antimicrobial Use Deck (11):
1

True/False. Antimicrobial use promotes selection of resistance bacteria, thereby reducing their therapeutic efficacy over time.

True.

2

What is rational antimicrobial use?

Antimicrobial agents aimed at maximizing therapeutic efficacy while minimizing the risks associated with development of resistance.

3

Which drugs are critically important antibiotics for everyone?

-Fluoroquinolones
-3rd generation cephalosporins
-Macrolides

4

What are examples of 3rd and 4th generation cephalosporins?

Cefovecin, cefpodoxime (small animals)
ceftiofur and cefquinome (food animals and horses)

5

What are examples of Fluoroquinolones?

Enrofloxacin, ciprofloxacin, marbofloxacin, etc.

6

Which drugs are the last resort drugs for human use?

Carbapenems
Linezolid
Vancomycin

7

Which drug has a narrow spectrum and is not licensed for use on animals?

Chloramphenicol

8

What is "shoot" regular, and which drugs are examples?

Time-dependent drugs (all beta-lactams) at regular intervals

9

What is "shoot" high, and which drugs are examples?

High doses for concentration-dependent drugs (fluoroquinolones and aminoglycosides)

10

What are two measures for control of AMR?

Control of antimicrobial use
Control of transmission

11

_______ refers to coordinated interventions designed to improve and measure the appropriate use of antimicrobials.

Antimicrobial Sterwardship