Receptors Flashcards

(36 cards)

1
Q

What transmitters act on Alpha 1 receptors?

A

Norepinephrine
Epinephrine
Dopamine

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2
Q

What transmitters act on Alpha 2 receptors?

A

Norepinephrine
Epinephrine

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3
Q

What transmitters act on Beta 1 receptors?

A

Norepinephrine
Epinephrine
Dopamine

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4
Q

What transmitters act on Beta 2 receptors?

A

Epinephrine

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5
Q

What transmitters act on depamine receptors?

A

dopamine

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6
Q

Where are the Alpha 1 receptors located?

A

Eyes
blood vessels
male sex organs
prostate capsule
bladder

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7
Q

Where are the alpha 2 receptors located?

A

nerve terminals (always presynaptic)

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8
Q

Where are beta 1 receptors located?

A

heart and kidney

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9
Q

Where are beta 2 receptors located?

A

lung
uterus
arterioles of heart, lung, skeletal muscle
liver

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10
Q

Where are the dopamine receptors located?

A

kidney

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11
Q

What is the function of the Ocular A1?

A

dilate pupil

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12
Q

What is the function of a1 receptors in the blood vessels?

A

vasoconstriction

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13
Q

What function does the alpha 1 receptors have on male sex organs?

A

ejaculation

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14
Q

What function does Alpha 1 receptors have on the smooth muscle of the bladder?

A

contraction

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15
Q

What function dose alpha 2 have on the presynaptic nerve terminals?

A

regulates neurotransmitter release or prevents release when there is too much transmitter in the synaptic gap.

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16
Q

What is the function of beta 1 receptors on the heart?

A

increases HR and force of contraction

17
Q

What is the function of beta 1 receptors on the kidney?

A

release renin to blood, which helps with vasoconstriction and increases BP.

18
Q

What is the function of beta 2 receptors on the lungs?

A

bronchial dilation

19
Q

What is the function of beta 2 receptors on the uterus?

A

relaxation of uterine smooth muscle

21
Q

What is the function of beta 2 receptors on the arterioles of the heart/lungs?

22
Q

What is the function of beta 2 receptors on the skeletal muscle?

23
Q

What is the function of beta 2 receptors on the liver and skeletal muscle?

A

glycogenolysis

24
Q

What is the function of dopamine receptors on the kidney?

A

dilates renal blood vessels to increase perfusion

25
What are the transmitters of the Peripheral nervous system (PNS)?
ACh NE Epi
26
What are the 3 cholinergic receptor subtypes?
Nicotinic M Nicotinic N Muscarinic
27
What transmitter can act on all three cholinergic receptors?
Acetylcholine
28
What is the location of the Cholinergic receptor Nicotinic N?
cell bodies of post-ganglionic neurons in the SNS and PSNS
29
What is the location of the Cholinergic receptor Nicotinic M?
skeletal muscle
30
What is the location of the Cholinergic receptor Muscarinic?
all organs regulated by the PSNS and sweat glands
31
What is the function of Nicotinic N on the cell bodies of post-ganglionic neurons in SNS & PSNS?
promotes ganglionic transmission in all ganglia of SNS and PSNS
32
What is the function of Nicotinic N on the adrenal medulla?
it promotes the release of Epi from the adrenal medulla
33
What function does Nicotinic M have on the skeletal muscle?
contraction of the skeletal muscle
34
What is the function of the muscarinic receptors on all organs of the PSNS and sweat glands?
elicits a response from the organ involved ex. decreases HR, contract ciliary eye muscle, urination, contraction of iris sphincter
35
What is an agonist?
a drug that binds to a receptor and causes the same reaction as the transmitter that normally binds to that receptor.
36
What is an antagonist?
A drug that binds to a receptor and prevents the reaction that would occur if the normal transmitter binds.