Receptors

Question 1

How many proteins are in an Ionotropic Receptor?

Answer 1

Consists of 5 proteins that form an ion channel.

Question 2

How many proteins are in an Metabotropic Receptor?

Answer 2

Consists of a single protein, in a long snake-like chain of amino acids, with 7 hydrophobic.
So called G-protein receptor.

Question 3

How are Ionotropic Receptors activated?

Answer 3

By a neurotransmitter or drug (ligand) that opens the channel, allowing ions to flow into or out of the cell.

Question 4

How are Metabotropic Receptors activated?

Answer 4

Activation by a neurotransmitter or drug (ligand) splits the receptor-coupled G-protein in two parts and induces biochemical changes.

Question 5

Are Ionotropic or Metabotropic Receptors faster at responding?

Answer 5

Ionotropic receptors are fasting as responding because although they are structurally complex, they are conceptually simple.

Question 6

How many binding sites to Ionotropic receptors have?

Answer 6

Multiple. Metabotropic usually have one.

Question 7

How do metabotropic receptors differ structurally from Ionotropic receptors?

Answer 7

They are a three-dimensional structure, whereas the Ionotropic has 5 peptides that form an ion channel.

Question 8

In the cell membrane, there are Na+ - K+ pumps, what do they do?

Answer 8

They adjust the levels of Sodium and Potassium in and out of the cell. Na+ moves out, and K+ moves in.