referrals

Question 1

GENERAL BLOOD DONATION FLOW

Answer 1

1. Donor Registration
2. Medical History Questionnaire
3. Counselling
4. Physical Examination
5. Informed Consent
6. Donation (Autologous, Directed, Apheresis)
7. Post-Donation Care

Question 2

donor registration - age for autlogous vs allogenic donation

Answer 2

● ALLOGENEIC DONATION: Minimum age >16 years

○ 16-17 years old: Requires Parental/Guardian Consent

○ 60-65 years old: Required Doctor’s Clearance

● AUTOLOGOUS DONATION: no age restriction

Question 3

weight requirement

Answer 3

● Weight: Minimum: 110 lbs or 50 kgs

Question 4

ADJUSTING ANTICOAGULANT (For underweight)

Answer 4

● Volume to collect = (donor’s weight in kg/50) x450 mL
● Volume of Anticoagulant= (Volume to collect/450) x 63
mL
● Volume of Anticoagulant to be removed = 63mL – Volume
of Anticoagulant

Question 5

Each blood bags contain how much anticogulant and how many ml of blood is usualllly inside

Answer 5

Each blood bags contain 63 mL of anticoagulant for 450
mL of Blood

Question 6

temp of donor must be

Answer 6

less than or equal 37.5

Question 7

pulse of donor should be

Answer 7

60-100bpm

Question 8

Blood Pressure of donor accd to aabb

Answer 8

: ≤180 mmHg (systolic) ; ≤100 mmHg
(diastolic)

Question 9

blood pressure requirement for donor as accodring to who

Answer 9

DOH: 90-160 mmHg (systolic); 60-100 mmHg
(diastolic)

Question 10

hgb requirement for allogeneic

Answer 10

≥12.5 g/dL (Hgb)

Question 11

Hematocrit requirement for allogeneic

Answer 11

≥38% (Hct)

Question 12

hgb for for autologous donations:

Answer 12

For Autologous donations:
■ ≥11.0 g/dL (Hgb)

Question 13

hct required for autologous

Answer 13

≥33% (Hct)

Question 14

HOW MANY DONATIONS CAN A MALE DO

Answer 14

Up to 6 donation (2 months interval)

Question 15

HOW MANY DONATIONS CAN FEMALES DO

Answer 15

Up to 4 donation (3 months)

Question 16

WHEN IS PREOPERATIVE COLECTION DON

Answer 16

5-6 weeks prior the procedure unless
units are frozen

Question 17

WHEN IS PREOPERATIVE COLLECTION USED

Answer 17

Orthopedic procedures, vascular surgery,
cardiac or thoracic surgery, and radical
prostatectomy

Question 18

Blood is collected at the start of surgery and then
infused during or after the procedure

Answer 18

ACUTE NORMOVOLEMIC HEMODILUTION

Question 19

WHAT IS THE HCT INA LIMITED AND SEVERE HEMODILUTION

Answer 19

● Limited Hemodilution: 28% Hct
● Severe Hemodilution: 21% or less

Question 20

Shed blood is recovered from the surgical field or
circulatory device then infused

Answer 20

INTRAOPERATIVE COLLECTION

Question 21

HCT FOR INTRAOPERATIVE COLLECITON

Answer 21

● Blood is concentrated to a Hct of 50-60%

Question 22

● Performed in urgent surgeries

Answer 22

INTRAOPERATIVE COLLECTION

Question 23

Shed blood is collected from the drainage devices
and reinfused to the patient

● May be reinfused with or without processing

Answer 23

POSTOPERATIVE COLLECTION

Question 24

● Microaggregate filter- sued to screen debris

Answer 24

POSTOPERATIVE COLLECTION

Question 25

WHAT HCT IS BLOOD CONCENTRATED IN IN INTRAOPERATIVE OLLECTION

Answer 25

● Blood is concentrated to a Hct of 50-60%

Question 26

Removal of blood or blood components as part of patient management

Answer 26

THERAPEUTIC DONATION

Question 27

WHEN IS THERAPEUTIC DONATION USED

Answer 27

● Hereditary Hemochromatosis, porphyria, Polycythemia vera

Question 28

is an effective method for collecting a specific blood component while returning the rest of the patient's whole blood components

Answer 28

Apheresis

Question 29

TYPES OF SEPERATION

Answer 29

● CENTRIFUGATION-BASED ● FILTER BASED

Question 30

reduces the recipient's donor exposure, enables compatibility matching, and allows for routine leukoreduction of the product.

Answer 30

PLATELETPHERESIS

Question 31

● Plateletpheresis unit is equal to

Answer 31

six to eight platelets units (3X10^11cells/uL)

Question 32

● Interval between plateletpheresis donation is

Answer 32

at least 2 days

Question 33

● Donor may not under go

Answer 33

more than 24 platelet phereses within 12 months

Question 34

● Infrequent/occasional vs serial based

Answer 34

○ Serial donors must undergo testing for total serum/plasma protein levels and quantitative immunoglobulin levels, as well as protein electrophoresis. ○ Infrequent- no more than once every 4 weeks ○ Serial: more than once every 4 weeks (must be at least 2 days apart and no more than 2 every 7 days

Question 35

● Specific drugs or Sedimenting agents for leukopheresis

Answer 35

○ Hydroxyethyl starch (HES) ○ Prednisone or dexamethasone

Question 36

Pulling the granulocytes from the marginal pool into the general circulation, thus increasing the supply of cells available for collection.

Answer 36

● Specific drugs or Sedimenting agents

Question 37

● Testing for the leukocytes' ________ is required for every leukapheresis product

Answer 37

● Testing for the leukocytes' HLA type, ABO group, and Rh type is required for every leukapheresis product

Question 38

● Red cell contamination in leukopheresi

Answer 38

> 2mL

Question 39

A process that collects Double units of red blood cells using apheresis equipment. (May be allogeneic or autologous)

Answer 39

DOUBLE RBC PHERESIS

Question 40

height and weight requirements of male and female in double rbc pheresis pati hct

Answer 40

○ Male: at least 130 pounds and 5'1" tall. ○ Female: at least 150 pounds and height of 5'5" ○ Acceptable hematocrit level 40%

Question 41

in double rbc pheresis

Answer 41

● If donation was stopped midway ○ >200 ml defer for 8 weeks ○ 200-300- defer 8 weeks ○ More than 300 ml- full 16 weeks

Question 42

what is used for aseptic

Answer 42

● Chlorhexidine gluconate and isopropyl alcohol.

Question 43

Maximum Volume

Answer 43

10.5 mL of blood per kg of donor’s weight, including samples for testing

Question 44

Low-volume

Answer 44

300-404 mL in 450 mL bag or 333-449 mL in 500 mL bag

Question 45

Anticoagulant

Answer 45

(1:8) 63 mL anticoag for 450 mL; 70 mL anticoag for 500 mL

Question 46

Time of Collection Usually,

Answer 46

< 10 minutes. If > 15min: Blood is not suitable for platelet and FFP

Question 47

Storage

Answer 47

20-24 C for platelets; otherwise, 1-6C