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Integrative Week Two > Renal > Flashcards

Flashcards in Renal Deck (84):
1

ADH

H20 reabsorption

2

Aldosterone

Na reabsorption
K excretion

3

Hypokalemia

hypo-osmolarity
insulin
alkalosis

4

Hyperkalemia

hyperosmolarity
insulin def
acidosis
lysis of cells

5

Metabolic Acidosis

decrease PCO2
decreased bicarb
immediate compensation - hyperventilate

6

Metabolic Alkalosis

increase PCO2, increase bicarb
immediate compensation - hypoventilate

7

Respiratory acidosis

increased PCO2, increase HCO3
delayed - renal bicarb reapsorption

8

Respiratory alkalosis

decreased PCO2, HCo3
delayed decreased bicarb reabsorption

9

RBC casts

Glomerulonephritis

10

WBC casts

pyelonephritis
transplant rejection

11

Fatty cats/oval fat bodies

nephrotic syndrome

12

Granular/muddy brown casts

ATN

13

Waxy casts

advanced renal disease/chronic renal failure

14

hyaline casts

nonspecifc

15

Minimal Change Disease

young
effacement of foot processes

16

Prerenal Azotemia

Urine Osm >500
Urine Na 20
FeNa 20

17

Intrinsic Renal Azotemia

Urine Osm 40
FeNa >2%
Bun/CR <15

18

Postrenal Azotemia

40 Urine Na
>1-2% FeNa
Bun/Cr > 15

19

increased anion gap

MUDPILES
methanol, uremia, DK, propylene glycol, iron tables or INH, lactic acidosis, ethylene glcol, salicylates

20

Decreased Anion Gap

HARD-ASS
hyperalimnetation, addison's disease, RTA, diarrhea, acetazolamide, sprionlactone, saline infusion

21

Metabolic Alkalosis Causes

loop diuretics
vomiting
antacid use
hyperaldosteronism

22

C-ANCA

anti-proteinase 3 antibodies
Wegners/GPA

23

P-ANCA

anti-myeloperoxidase antibodies
Churg Strauss
polyangiits

24

Anti-GBM Antibodies

Good Pastures

25

def of von Willebrand factor cleaving protease

TTP

26

bladder cancer

older patient
smoker
microscopic hematuria

27

Renal Cell Carcinoma

hematuria, flank pain
high HCT/Ca
left sided variocele
fever

28

Nephrolithiasis

Flank pain
can't sit still
hematuria

29

Membranous Nephropathy

granular casts
oval fat bodies
nodules in lung

30

Minimal Change Disease

NS, young person
fusion of foot processes

31

solid tumor or Hep B

membranous nepropathy

32

Membranoprolifative GN

NS, nephritis
Hep C

33

Focal Collapsing segmental glomerulosclerosis

HIV untreated
NS

34

Renal Vein Thrombosis

NS
flank pain/hematuria
loss of clotting factors

35

Wilm's Tumor

deletion of 11p
hematuria
palpable mass in right flank

36

Trastuzumab

Her2/neu

37

Aniridia and hemihypertrophy

Wilms

38

Neuroblastoma

neural crest tumor
elevated urine vanillylmadelic acid

39

Nonseminoma

swollen left testicle
high alpha-fetoprotein
B-HCG

40

CA 125

ovarian cancer

41

urge incontinence

detrustor muscle hyperactivity

42

overflow incontinence

sacral lower motor neuron dysfunction

43

stress incontinence

loss of ureterovesicular angle with vaginal atrophy

44

adnexal and cervical motion tenderness

PID

45

vaginal yeast

ph <4.5
white discharge

46

painless, indurated, clean base

syphilis
T. pallidum

47

deep, purulent ulcer
tender adenopathy

Chancroid
H. ducreyi

48

Multiple shallow ulcers
painful

Herpes, HSV2

49

Proctitis
tender draining inguinal LN
anorectal ulcers

lymphogranuloma vereuaum (C. trachomatis 1-3)

50

Jarish-Herxhemier reaction

massive cytokine release as spirochetes are killed
hypotension, fever

51

clue cell

bacterial vaginosis

52

hyphae

candida

53

ethylene glycol poisoning

elevated K
low bicarb
oxalate crystals

54

Symptoms of Prerenal Azotemia

vomitting, diarrhea
FeNa<10

55

Rhabdomyolysis

muscle breakdown (statins, seizure, trauma)
large blood, 0 RBC

56

ATN

hypotension
muddy brown casts
epitherlial cells
urine sodium elevated

57

Atheroembolic Disease

post cardiac cath
livedo reticularis
eosinophils

58

AIN

PCN/NSAID use
urine or serum eos
WBC casts

59

Post-infectious GN

post pharyngitis
AKI
RBC Casts, low C3, normal C4

60

Goodpasture's

pulmonary sx, AKI
RBC casts, normal C3, C4
anti-GBM, type II hypersensitivity

61

Wegner's

cANCA
pulm sx, sinus sx/nasal polyps
AKI, RBC casts

62

IgA nephropathy

recurrent hematuria with viral infections
IgA mesangial deposition

63

Alports

boy, hearing loss, ocular findings, hematuria

64

Urge incontinence symptoms

freuqent need to go
incomplete voiding

65

Stress incontinence symptoms

loss of continence with cough/sneeze

66

Overflow incontinence symptoms

contiuous leakage, neurodysfunction (MS, DM)

67

functional incontinence

older person, dementia, debilitated

68

Primary Syphilis

painless ulcer

69

Secondary Syphilis

rash (esp. palms), fever, LAN

70

Tertiary Syphilis

tabes dorsalis
Argyll Robertson pupil
aortitis
gummas

71

Jarisch-Herxheimer symptosm

fever, hypotension, rigors

72

Chylamydia gram stain

gram negative
coccoid/rod

73

Gonorrhea gram stain

gram negative diplococci

74

staghorn calculus

urease producing
proteus or klebsiella

75

multiple kidney cysts

ADPKD
berry anuerysms
ARPKD in kids

76

Testicular torsion

sudden onset testicular pain
no better with elevation

77

Tumor lysis syndrome

AKI post Rx for lymphoma
ALL
high uric acid, phosphate, k

78

Drugs that Cause ATN

aminoglysides
vancomycin

79

AIN Drugs

penicillins, NSAIDS

80

cyclophosphamide

hemorrhagic cystitis

81

older man, URI, acute urinary obstruction

cold med
anticholinergics/diphenhydramine

82

treatment for BPH

finasteride
tamsulosin

83

finasteride

5 alpha reductase inhibitor

84

tamsulosin

alpha blocker