Renal Related Terms Flashcards

1
Q

PAH

A

P - Amminohippurate Transport, which is a transport system.

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2
Q

Ionomycin

A

This is a calcium ionophore that increases cytoplasmic Ca2+ levels.

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3
Q

BAPTA-AM

A

This is a Ca2+ chelator which reduces cytoplasmic Ca2+ levels.

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4
Q

TMB-8

A

This is an agent that inhibits efflux of Ca2+ from intracellular stores.

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5
Q

Phorbol-12-myristate 13-

acetate (TPA)

A

This agent is a PKC activator.

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6
Q

Mineralocorticoid

A

This is a steroid hormone that plays a role in regulating salt and water balances.

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7
Q

Glucocorticoid

A

These are corticosteroids that are a class of steroid hormones.

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8
Q

Adenylate and Uridylate rich elements

A

The Na/K ATPase B subunit mRNA has these elements in the 3’ UTR (Untranslated Region) and may affect mRNA stability or translational efficiency.

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9
Q

SV40 T Antigen

A

These are large and small T Antigens, that are regulatory proteins encoded by SV40. Large T Antigen is responsible for cellular and viral transcription regulation, virion assembly, viral DNA replication and alteration of the cell cycle.

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10
Q

Alkaline Phosphatase

A

This is a brush border enzyme responsible for breaking down proteins in the body and exists in different forms depending on where it originates.

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11
Q

Gamma glutamyl transpeptidase

A

This is an enzyme that removes glutamyl groups from aromatic amines to other amine receptors on peptides or amino acids.

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12
Q

Medium K-1

A

This is medium (DMEM: Hams F12) with T3, hydrocortisone, insulin, transferrin and PGE1.

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