renal remediation Flashcards

(58 cards)

1
Q

anion gap metabolic acidosis

A

MUDPILES

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2
Q

TRH or TSH from hypothalamus

A

TRH

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3
Q

stimulates release of ACTH

A

CRF

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4
Q

PIF

A

inhibits prolactin release - hypothalamic hormone

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5
Q

peptide hormone stimulatingcell repro, growth etc

A

GH

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6
Q

from hypothalamus stimulating GH

A

GHRH

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7
Q

function of GnRH

A

release of LH and FSH

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8
Q

most common cause of nephritic syndrome

A

bergers

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9
Q

recurrent gross or microscopic hematuria

A

bergers

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10
Q

gross hematuria post URI

A

bergers

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11
Q

IgA deposits in the mesangium of glomerulus

A

bergers

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12
Q

collecting duct function

A

water reabsorption and sodium retention via ATPase

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13
Q

cells that actively reabsorb sodium in the CD

A

principle cells

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14
Q

tumor associated with excessive ACTH and cushings

A

small cell carcinoma of the lung

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15
Q

indication the small cell ca is cause of cushings syndrome

A

hypercortisolism that is not suppressed by low or high dexamethazone tests

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16
Q

cushings disease only refers to hypercortisolism by

A

ant pit

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17
Q

doesnt respond to dexamethasone

A

small cell cancer, primary adrenal hypercortisolism

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18
Q

most common endogenous cushings

A

pituitary adenoma

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19
Q

most common cause of cushings overall

A

iatrogenic

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20
Q

connection btwn cortisol and DM

A

hypercortisol = decreased insulin sensitivity

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21
Q

tests for cushings syndrome

A

24 hr free urine cortisol, dexamethasone suppression test

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22
Q

cystinuria

A

defect in aa transport in the proximal tubule

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23
Q

cystine

A

two cysteine bound by sulfide

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24
Q

cyanide on cystine

A

breaks disulfide bond

25
sodium nitroprusside
turns cysteine fluid red/purple
26
cystinuria stones
staghorn
27
complication of DIC
renal failure
28
hormones that act on distal tubule
aldosterone and vassopressin
29
parathyroid hormone effect at DT
Ca reabsorption
30
lysogeny
infection with a prophage that contained coding for the toxin
31
accumulation of ceramide trihexoside from deficiency of alpha galactosidase A.
fabry's
32
common cause of death in Fabry's
end stage renal failure in 3rd decade - proteinuria
33
possitive or basic aa transport defect
cystinuria
34
nuetral aa transport deficiency in GI and kidneys
hartnup
35
vitamin deficiency of hartnup
niacin - pellagra
36
ANP released from where
aorta - inresponse to HTN
37
ANP action
vasodilator, and (inhibits renin)
38
dehydropeptidase 1 inhibitor
cilastatin
39
carbapenems
imipramine and meropenem
40
common side effects of carbepenems
GI distress (NVD) and skin rash
41
tx of drug overdose of aspirin or barbiturates
Mannitol
42
C3 nephritic factor
type 2 membranoproliferative GN - binds and stabilizes C3 convertase - hypocomplementemia
43
another name for type 2 MPGN
dense deposite disease
44
PCOS
polycystic ovary syndrome - tx metformin
45
symptoms of hypercalcemia
bones, stones, abdominal groans, and psychiatric overtones
46
normal BUN:creatinine ratio
10-20 - also postrenal failure
47
BUN:Cr > 20
prerenal failure
48
BUN:Cr < 10
intrinsic renal failure
49
causes of acute prerenal injury
decreased CO, overdiuresis, cardiogenic shock
50
albuminuria in a child that has just overcome flu
minimal change disease
51
Minimal change in adults
hodgkins lymphoma
52
nonenzymatic glycosylation of vascular BM resulting in hyaline arteriosclerosis
diabetic glomerulonephropathy
53
type 4 collagen deposition
diabetic gn
54
expanding mesangium increased filtration
diabetic GN
55
conditions associated with FSGS
HIV, Heroin, sickle cell, massive obesity
56
sequelae of IgA nephropathy
FSGS
57
number 1 glomerulonephritis worldwide
IgA /Bergers
58
anion gap met acidosis
remember aspirin, iron, isoniazid