REPLICATION Flashcards
(21 cards)
3 subunits of dna structure
phosphate group
sugar
n base
how many bonds are there in A;T pairing
2
how many bonds are there in C;G pairing
3
hydrogen are weak or strong bonds?
weak
the process by which doublestranded DNA molecule is copied to produce two
identical DNA molecules
DNA replication
Each of them would be a complex of an old (parental) and a daughter strand.
semiconservative replication
DNA double helix made of two daughter strands while the parental chains would stay together.
conservative replication
Replication Process would create two DNA doublechains, each of them with parts of both parents and daughter molecules
dispersive replication
the Semiconservative DNA
Replication as was proven by the experimentation of …
Matthew Meselson and Franklin Stahl
DNA replication occurs during the interface, particularly in the … phase because it is in this phase where the cells are growing, and performing cellular tasks and
replicating
synthesis phase (s phase)
true or false: DNA has to divide first before it is copied
false
3’ - 5’, synthesizes the leading strand
continuous replication
Occurs in short segments called OKAZAKI fragments, synthesizes the lagging strand
Discontinuous replication
Also called the unzipping enzyme
Helicase
o Synthesizes short oligonucleotides (primers)
→ Also called as the initializer because it creates primer so that the DNA polymerase can figure out where to go and where to start replication
Primase
Allows the leading strand to be threaded through
Clamp protein
Acts as a builder because it adds new nucleotides
DNA polymerase
Termed as the gluer because it glues DNA fragments together. Joins Okazaki fragments in the lagging strand
ligase
synthesized continuously as a
single strand from the point of origin toward the opening
replication fork
Leading strand
synthesized discontinuously
against overall direction of replication
Lagging strand
series of short segments on the
lagging strand
okazaki fragments
