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4 MBCHB > REPRO 5 > Flashcards

REPRO 5 Flashcards

(62 cards)

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1
Q

plasma volume increases by how in pregnancy leading to what

A

50%

anaemia

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2
Q

BP does what
GFR
CO

A

goes down in second trim
up leading to decreased CR and UR
increase - systolic ejection murmur

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3
Q

ACEI/ARBs

A

renal hyperplasia

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4
Q

androgens

A

civilisation of females

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5
Q

anti epileptics

A

cardiac, facial , NT

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6
Q

cytotoxic

A

multiple defects, abortion

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7
Q

lithium

A

CDV

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8
Q

methotrexate

A

skeletal

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9
Q

retinoids

A

ear, CDV, skeletal

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10
Q

warfarin

A

limb and facial

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11
Q

tetracycline

A

stains bone and teeth of kids

avoid in children under 8

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12
Q

phenytoin

A

cleft lip and palate

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13
Q

stillbetrol

A

vaginal adenocarcinoma in girls

urological malignancy in boys

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14
Q

valproate

A

NT

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15
Q

warfarin around labour

A

bleed

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16
Q

opiates around labour

A

resp depression - prem closure of DA

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17
Q

SSRI opiates

A

NAS

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18
Q

phenybarbitone in breast feeding

A

suckling difficulties

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19
Q

amiodaron in breast feeding

A

neonatal hypothyroidism

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20
Q

cytotoxic in breast feeding

A

BM suppression

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21
Q

BZDs in breast feeding

A

drowsiness

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22
Q

bromocriptine in breast feeding

A

surpasses lactation

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23
Q

rx for N/V

A

cyclizine

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24
Q

rx for UTI

A

nitro and ceflaxine

trim in 3rd trim

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25
pain rx | heart burn
paracetamol | antacids
26
epilepsy in pregnancy why does the seizure rate go up
non compliance | changes in plasma concentration - committing and increased clearance
27
what does frequent seizures lead to
low IQ, brady, IUD, maternal death
28
treatment of epilepsy
5mg FA 3m prior to conception and throughout | vit K 34-36w 20mg PO if taking hepatic enzyme inducers
29
risk of child developing epilepsy
5% if mum/dad 15% if both mum and dad 10% if sibling and mum/dad
30
anti epileptics SE
NTD, orofacial, cardiac, | fetal anticonvulsant syndrome: dysmorphic features, hypo plastic nails and distal digits
31
stopping phenobarbital
neonatal withdrawal convulsions
32
scans during epilepsy
detailed metal scan at 18-20w | detailed cardio scan at 22w
33
cs when in epilepsy
recurrent gen seizures in late pregnancy or labour
34
post partum in epileptic mothers
neonates IM 1mg vit k
35
pre existing DM leads to what in pregnancy
poorer control | renal and eye deterioration
36
what DM drug is not safe in pregnancy
SUs
37
GDM
fasting glucose >=5.6 2hours >=7.8
38
target for fasting | 1h after meal 2h
5. 3 7. 8 6. 4
39
retinal screening when
every trim
40
postnatal follow up of BG
stop treatment and moniter for 24 hours
41
fetal macrosomia can lead to what | c section when
should dystocia | >4kg
42
polyhydraminoas risk of what
preterm, malpresentation, cord collapse
43
polycythaemia risk of what
unexplained stillbirth, thrombotic events, jaundice
44
neonatal hypoglycaemia risk of what
cerebral palsy
45
IOL when in pre existing DM | GDM on insulin
37-18w | 38w
46
important to monitor for what in DM
PET
47
pregnancy has a what fold risk of VTE
10 fold
48
what is the leading cause of maternal death
VTE
49
why does pregnancy have a high risk of VTE
increase in factors 7, 8, 10, fibrinogen | decrease in protein S
50
low risk for VTE treatment
mobilise and keep hydrated
51
intermediate risk for VTE rx
consider LMHW proph
52
high risk for VTE rx
LMWH proph
53
dose of LMWH in pregnancy and for how long
1mg/kg | 3m after birth or 6m after beginning of treatment
54
heparin SE
haemorrhage, h/s, osteopenia, heparin induced thrombocytopenia
55
warfarin SE
teratogenic, haemorrhage
56
when should heparin be stopped | planned delivery what
24 before | give proph dose 12h before
57
hypothyroid rx
increase levothyroxin by 25-50mcg in first trim
58
hyperthyroid why does it get worse in first trim
because of HCG
59
risks of hyperthyroid
IUGR, prem, thyroid storm
60
rx for hyperthyroid
PTU
61
thyroid and pregnancy monitoring
TFTs every trim
62
anaemia when to give oral iron at booking | at 28 weeks
<11g/dl | <10.5

4 MBCHB (80 decks)

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