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FA - Reproduction > Repro1 > Flashcards

Repro1 Flashcards

1
Q

What are the important genes of embryogenesis?

A

Sonic Hedgehog gene
Wnt-7 gene
FGF gene
Homeobox (Hox) gene

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2
Q

Where is sonic hedgehog gene produced?

A

Base of limbs in Zone of Polarizing activity

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3
Q

What is sonic hedgehog involved in?

A

Patterning along Anterior-Posterior Axis

CNS development

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4
Q

A mutation in Sonic Hedgehog gene can cause what?

A

Holoprosencephaly

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5
Q

Where is Wnt-7 gene produced?

A

Apical Ectodermal Ridge

-thickened ectoderm at distal end of each developing limb

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6
Q

Wnt-7 gene is necessary for what?

A

Proper organization along dorsal-ventral axis

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7
Q

Where is FGF gene produced?

A

Apical ectodermal ridge

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8
Q

What is the role of the FGF gene?

A

Stimulates Mitosis of underlying Mesoderm

-Lengthening of limbs

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9
Q

What is Homeobox (Hox) genes involved in?

A

Segmental organization of embryo in the Craniocaudal direction

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10
Q

What happens in Hox mutations?

A

Appendages in wrong locations

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FA - Reproduction (6 decks)

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