Reproduction-sex Differential Flashcards
Where are both males and females sex derived from? And by what?
Primordial germ cells (yolk sac) from dorsal endoderm migrate to urogenital ridges
The primordial gonads are differentiated or undifferentiated?
Undifferentiated
Up until what week are the gonads differentiated?
6 weeks
In a male, when do testes begin to develop?
7th week
What gene triggers development of urogenital ridge?
Where is it found?
SRY gene
Y chromosome
In females, there is no Y chromosome, so what happens to the gene?
No SRY gene
Before the functioning of the fetal gonads, the undifferentiated reproductive tract includes a double genital duct system comprised of the:
- Wolffian ducts
- Mullerian ducts
- Common opening to the outside for the genital ducts & urinary system
Male Chromosomes? SRY gene present? What cells present? What do they produce?
XY
Yes
Sertoli=produce anti mullerian hormone (AMH)
Leydig cells= testosterone
Male
What does the AMH and testosterone cause to occur?
Regression of female (mullerian) structures
Wolffian structures delvelop (tested + sperm)
What wolffian structures are produced by testosterone?
Epididymis
Vas deferens
Ejaculatory ducts
Seminal vesicles
What hormones produce the external genetalia?
Enzyme?
Testosterone—(5 alpha reductase)—> dihydrotestosterone
What structures does dihydrotestosterone produce?
Penis and scrotum
Female Chromosome? SRY gene present? What cells present? What do they produce?
XX
No
No sertoli = no AMH
No leydig = no testosterone
With the absence of testosterone and AMH, what develops?
No AMH = mullerian system develops
Vagina, uterus, ovaries, ova
No testosterone = wolffian ducts regress
What weeks are the ovaries present by?
11 - 12 weeks
