Reproductive Development Flashcards Preview

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Flashcards in Reproductive Development Deck (59)
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1

How is genital ridge formed

Primordial cells from yolk sac migrate into intermediate mesoderm
Medial to urogenital ridge

2

Which part of genital ridge proliferates?

Epithelial part

3

Primitive sex cords

Migrating germ cells that have become surrounded by epithelial cells

4

Mullerian ducts

Paramesonephric ducts
Arise lateral to mesonephric ducts
Cuadal ends fuse and connect to urethra

5

Male/female genetic

46XY
46XX

6

TDF

Transcription factor that controls cascade of events leading to male development

7

SRY

Sex determining region of Y chromosome
Where TDF is located

8

Virilization

Development of adult male characteristics

9

How does female development occur?

If TDF is absent

10

SRY gene expression induces

TDF production
differentiation of sertoli cells

11

Sertoli cells

Main organizer of testes
Product Amh and recruit leydig cells

12

Anti-mullerian hormone

Amh
Secreted by sertoli
Degenerates paramesoneprhic ducts

13

Leydig cells

Interstitial cells
Secrete testosterone
Recruited by sertoli cells

14

Testosterone

Causes survival of mesoneprhic duct

15

Mesonephric ducts become

Male genital sex ducts

16

5-alpha 2 reductase

Converts testosterone to dihydrotestosterone

17

Dihydrotestosterone

Responsible for differentiation of male EXternal genitalia and secondary sex characteristics at puberty (virilization)

18

Testis cords composed of

Sertoli cells and germ cells

19

Testis cords also called ____ and produce _____

Medullary cords
Amh

20

Rete testis

Sertoli cells and NO germ cells

21

Tunica albuginea and lobules of testes formed by

Non-prenetrating epithelial cells

22

Mesoneprhic ducts open into the

Urogenital sinus

23

Mesoneprhic tubules fuse with ___ to form _____

Mesoneprhic tubules
Efferent ductules

24

Mesonephrous derived structures

Efferent ductules
Epididymis
Ductus defernes
Seminal vesicles

25

Paramesonephric duct degenerated by

Amh
Except for prostatic utricle and appendix testis

26

Female epithelial cells differentiate to

Follice cells that surround primitive germ cells

27

Primordial follices

Follicle cells + germ cells

28

Meduallry region of ovary contains

Neurovascular structures

29

In female, mesonephric degenerates except for

Epoophoron
Paroophoron
Gartner's Cyst

30

Paramesonephric ducts develop into 3 parts in female...what are they?

Cranial vertical - uterine tube
Horizontal - uterine tube and superior uterus
Caudal vertical - inferior parts of uterus