Reproductive Hormones Flashcards
(25 cards)
what does progesterone do
inhibits secretion of LH
has thermogenic effect increases basal body temperature
relaxes smooth muscle
what does progesterone do to the mucus
responsible for infertile mucus, opaque, sicky thick, non stretchable, non fern pattern when dry
what does progesterone do to the endothelium
maintains thickness
describe the follicular phase
as dominant follicle develops it produces increasing amoutns of follicular fluid containing estrogen
estrogen stimulated thickening of the endometrium
increase in serum estrogwn suppresses secretion of FSH and favours secretion of LH
LH stimulates ovulation
what stimulates ovulation
LH production
what is the luteal phase
follows ovulation
cavity of ruptured follicle is replaced by the corpus luteum (secretes progesterone and some oestrogen)
progesterone stimuales secretory changes in endometrium to prepare for implantation
if no fertilisation then corpus luteum begins to regress and decrease in progesterone and estrogen
what is the menstrual phase
corpus luteum degenerates
cessation of progesterone and estrogen production by the corpus luteum
endometrium degeneration and menstruation occurs
drop in blood levels of oestrogen and progesterone stimulate production of FSH and new cycle begins
what happens when LH surges
oocyte resumes meiosis
previously stopped at prophase in meiosis I continues until metaphase II where it stops
when is oogenesis completed
only completed if fertilised
how much after the surge of LH is ovulation
36.5 hours later
what forms the corpus luteum
collapsed follicle
when does oogenesis for females begin
begins in utero, mitotic division of oogonia and commence 1st meiotic division of primary oocyte
how do we detect ovulation
lutein is an orange/yello carotenoid pigment
granulosa cells luteinised
increase production progestogens, progesterone and 17a hydroxyprogesterone
what day are progesterone levels usually measured to assess whether ovulation has taken place
day 21 (7 days before next period)
which hormone is essential for spermatid remodelling
FSH
what does LH do in males
regulate testosterone secretion
what hormone decreases secretion of FSH
Inhibin
what do sertoli cells secrete
androgen binding globulin and inhibin
where are sertoli cells found
in seminiferous tubules
what decreases the release of GnRh and LH
testosterone
how does estrogen increase the water content of the uterus
mildly accelerates na and h20 reabsorption by kidney tubulues
what does a high oestrogen concentration do to FSH
high oestrogen concentration inhibits secretion of FSH and prolactin
what does a low oestrogen concentration after pregnancy help stimulate
secretion of prolactin for breastfeeding
what does a high estrogen do to LH
stimulate the production of LH