Research Methods Flashcards
X-ray computed tomography;
Computer assists in reconstructing 3-D structure of the brain from many individual “slices”.
Positron Emission Tomography;
Inject / inhale a radioactive isotope
Inject a contrast substance to accentuate the difference between the target tissue and surrounding tissue.
Which technique has the best spatial resolution of the structure of the living human brain?
Which technique has the best temporal resolution of brain function?
In electroencephalography, the P300 wave is…
a commonly observed response that occurs 300 milliseconds after stimulation
Magnetic Resonance Imaging
Detects the waves emitted from hydrogen atoms when in a magnetic field.
Functional Magnetic (fMRI)
- Captures areas of increased oxygenated blood flow in the brain.
- More active areas take up more oxygenated blood.
- Oxygenated blood has magnetic properties.
Blood Oxygen Level Dependent signal.
Transcranial Magnetic Stimulation (TMS)
Single magnetic pulses are applied to specific locations on the scalp at specific times during a behavioural task; or repetitively prior to task performance
• Measures changes in the magnetic
fields on the surface of the scalp.
• Very good temporal resolution
• Poorer spatial resolution.
Individual signals are noisy
The average is informative