Resp Practice Questions Flashcards

(59 cards)

1
Q

What are the three classes of quick acting respiratory agents?

A

Anticholinergics, beta, two agonist, oral corticosteroids

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2
Q

Which quick acting drug class is used to be taken prior to known trigger onsets

A

The beta two agonist like albuterol and levalbuterol

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3
Q

Which beta two agonist works quicker

A

Albuterol

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4
Q

How soon before exercise triggers should you take a short acting beta to agonist

A

10 to 20 minutes before

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5
Q

Which beta two agonist has less effect on a heart rate

A

Levalbuterol

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6
Q

How do the short acting beta to Agnes cause relaxation of the bronchial smooth muscles?

A

They stimulate the release of intracellular adenocyclase

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7
Q

Why do short acting beta, receptors commonly cause significant cardiovascular effects?

A

About 50% of beta receptors are located in the heart. Treatment with albuterol and levalbuterol, can lead to tachycardia and angina.

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8
Q

Which class of quick acting respiratory medication’s is commonly used in patients with poorly controlled Asthma for a short term courses.

A

Oral systemic corticosteroids

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9
Q

When should you reevaluate patients taking oral systemic corticosteroids?

A

In 2 to 6 weeks after prescribing

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10
Q

Which class of quick acting respiratory meds is more commonly used in COPD

A

The anticholinergic ipratropium

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11
Q

Does ipratropium have a systemic or local effect?

A

It has a local effect and therefore causes less adverse effects on the body

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12
Q

What did the adverse effects of the anticholinergic ipratropium

A

Dry mouth, irritation of the pharynx, headache

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13
Q

What are the leukotriene agonist used for?

A

Mild to persistent, asthma, and allergic rhinitis

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14
Q

Which leukotriene agonist has the least drug interactions

A

Montelukast

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15
Q

How did the leukotriene agonist class work?

A

They decrease, inflammation, bronco construction, edema, mucus, secretion, and recruitment of eosinophils

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16
Q

Which drugs do the leukotriene agonist zileuton and zofirlukast interact with

A

Warfarin and theophylline

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17
Q

What increases the bio availability of leukotriene agonist?

A

Taking in a fasting state

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18
Q

What are the adverse effects of leukotriene agonist?

A

Headache and GI effects

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19
Q

Which leukotriene agonist does not cause liver injury

A

Montelukast

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20
Q

What are the three leukotriene agonist drug names?

A

Zileuton, zofirlukast, montelkast

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21
Q

What is the most commonly used long acting beta agonist

A

Salmetrol

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22
Q

How long do LABAS work?

A

12 to 24 hours

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23
Q

When are long acting beta agonists indicated

A

Only in use with an anti-inflammatory agent when using for asthma like inhaled corticosteroids
It can be used as maintenance therapy alone for COPD patients

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24
Q

How is the mast cell stabilizer, chromeylin sodium administered

A

Only by nebulizer four times a day until your stabilized, then you can possibly go down to three times a day

25
How do the mast cell stabilizer, chromeylin sodium work for asthma?
It inhibits degranulation of mast cells and suppresses inflammation. It is the least effective for asthma treatment.
26
What are the side effects of cromolyn sodium
Congestion, cough, sneezing, nausea
27
What is the most effective and preferred treatment for asthma?
The inhaled corticosteroid class like budesonide and fluticasone
28
Which inhaled corticosteroid can be taken only once daily instead of twice daily
Fluticasone
29
Which inhaled corticosteroid is safe to use in pregnancy
Budesonide
30
How does the inhaled corticosteroid class work for asthma?
They inhibit production of inflammatory agents like cytokines, macrophages, and leukotriene’s and acts locally on the lungs
31
When are inhaled corticosteroids considered for COPD?
Only when patients fall into group, E
32
What are the local adverse effects of inhaled corticosteroids?
Dysphonia, topical candidia, contact, hypersensitivity, cough
33
What are the systemic adverse effects of inhaled corticosteroids?
Adrenal suppression like HPA down regulation, lung infection, ocular effects, like cataracts, skeletal affects, like osteoporosis, and growth inhibition in children
34
What are the immunomodulators?
Omalizumab, mepolizumab, reslizumab, benralizumab, dipliumab
35
What are immunomodulators indicated?
Only impatience that are older than the age of 12 with moderate to severe asthma and has failed prior inhaled corticosteroids and has a positive allergy skin test to perennial areo allergen
36
What two task can be done for patients prior to starting immunomodulators
An allergy skin test or an IGE blood test
37
What is the biggest barrier to immunomodulators?
Costs up to 30000 a year
38
What are the risks of taking immunomodulators
Increased risk for cancer, cardiovascular, and cerebral vascular events
39
What drug is in the methylzanthine class?
Theophylline
40
When is theophylline used the most?
When patients cannot afford other classes of medication’s
41
How does theophylline work?
Bronchodilation, anti-inflammatory and bronco protective effects
42
Which class of anti-asthma medication’s has the most unpredictable pharmacokinetics
Methylzanthine class theophylline
43
True or false Theophylline can be given in pregnancy
F it is category C
44
What three classes can be given in COPT as a triple therapy
Inhaled corticosteroids, long-acting, miscarriage agents, long acting, beta agonist
45
When are the methylxanthine’s used IV and COPD?
When there is an insufficient response to short acting bronchodilators
46
What PPD for inhibitor is used in COPD to reduce exacerbation and chronic bronchitis
Roflumilast
47
If eosinophils are less than 100 cells rather than starting the triple therapy what other medication regimen could you try?
Roflumilast or azithromycin
48
What medication regimen do you start when eosinophils are greater than 300?
Triple therapy
49
What level of O2 would you want to keep saturation at in hypoxic COPD patients?
Greater than 90%
50
How often would you recheck to excessive oxygen therapy is still needed after initiating
In 60 to 90 days
51
What are the symptoms of all allergic rhinitis?
Sneezing, pruritis, nasal congestion eye watering
52
Which class of medications are preferred for the first line use of allergic rhinitis
Non-sedating second generation antihistamines
53
What are the oral decongestant or sympathomimetics used for allergic rhinitis?
Sudafed and the phenylphrine
54
What class of medications is used for persistent or perennial allergic rhinitis symptoms?
Internasal corticosteroid spray
55
What do you start if internasal share spray does not control allergic rhinitis symptoms
An oral or intraocular antihistamine
56
What are the two opioid antitussives suppress cough?
Codeine and hydrocodone
57
What is the non-opioid antitussive
Dextromethorphan
58
What is the commonly used exectorant
Guaifenesin
59
At what age are Antitussives not recommended in children?
Five years old and younger