Respi Drugs Flashcards
(20 cards)
discuss COPD
MC symptom: cough
MC cause: smoking
- pwede din pollution, gas or others
discuss asthma
reversible bronchoconstriction - allergy
diff in exhale
discuss emphysema
destruction of alveoli
pink puffer
discuss chronic bronchitis
inflammation of bronchus and bronchioles
blue bloater
discuss antitussives
cough suppressant - for dry or non prod
can cause sedation and dizziness
discuss antitussives opioid derivatives
semi synthetic - prescribed not OTC
can cause sedation or high if OD
discuss antitussives non-opioid derivatives
diphenhydramine - benadryl
milder form usually for elders
sedative and acts as antihistamine
discuss mucolytics/expectorants
for prod cough - mucolysis to excrete phlegm
can cause nausea and vomit, stomatitis and rhinorrhea
discuss decongestants
alpha 1 agonist and sympathomimetics
causes vasoconstriction - reduce inflammation and secretion
adverse effect
- vascular HA
- dizzy
- nervousness
antihistamines c CNS effects
diphenhydramine
chlorpheniramine
clemastine
promethazaine
brompheniramine
discuss bronchodilators
stims bet 2 receptors = dilation
adverse effects:
dry mouth
constipation
urinary retention
tachycardia
blurred vision
confusion
discus beta adrenergic agonists
1.1 mixed - beta 1 and 2
discuss xanthine derivatives
Relax airway muscles and improve breathing
- Phosphodiesterase (PDE) inhibition - increase cAMP = bronchodilation
- Adenosine receptor blockade - prevent bronchoconstriction and reduces inflammation
IV
discuss anticholinergic drugs
inhib Ach in PSY = smooth muscle relax and dec secretions
inc HR also
discuss anti-inflammatory agents
oral or inhaled steroids or IV
corticosteroid - anti inflamm; treats attack
cromolyn sodium - mast cell stab; inhib release of histamine and leukotrienes
- prophylaxis - prevention and maintenance
discuss bactericidal anti-TB
active eradication
Isoniazid
Rifampicin
Levofloxacin
Streptomycin
Pyrazinamide
discuss bacteriostatic anti-TB
Inhibit growth and replication
Ethambutol
Aminosalicylic Acid
Ethionamide
discuss drugs for anti TB
combined bacteriocidal and static
taken in the morning c empty stomach
treatment duration in anti TB
Standard treatment - 6 months
Drug resistant - 9-24 months
Special cases ((meningitis, bone, HIV) - 9-12 months
TB considerations in PT
TB is contagious
Isoniazid may cause neurologic symptoms
Patients may easily fatigue while on anti-TB medications
