Respiratory Flashcards

1
Q

IV salbutamol can cause what electrolyte abnormality? - what monitoring is needed to identify this?

Which of the following would be used in:

a) moderate asthma attack
b) severe asthma attack
c) life threatening asthma attack

  • IV aminophylline
  • Nebulised salbutamol
  • IV magnesium sulphate
  • Nebulised ipratropium bromide
  • IV salbutamol
  • Intubation
A

Salbutamol causes K to move from serum into cells = hypokalaemia
~
need to monitor serum K

Moderate asthma attack:
• Nebulised salbutamol
• Nebulised ipratropium bromide

Severe asthma attack:
• IV aminophylline
• IV salbutamol

Life threatening attack:
• IV magnesium sulphate
• Intubation

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2
Q

List some common symptoms of asthma: (3)

A
  • Wheeze
  • Cough (worse at night)
  • SOB
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3
Q

What symptoms does COPD commonly present with? (4)

A

Chronic SOB

Productive cough

Wheeze

Recurrent respiratory tract infections

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4
Q

What is Sarcoidosis?

Sarcoidosis can affect any organ in the body, however which organ is most commonly affected?
~ What symptoms may you see if this organ is affected? (3)

A

A granulomatous inflammatory condition

Lungs!
~ Bilateral mediastinal lymphadenopathy
~ Pulmonary fibrosis
~ Pulmonary nodules

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5
Q

A diagnosis of COPD is based upon the results of what? (2)

A

Clinical presentation (symptoms + history)

Spirometry

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6
Q

What condition would the following indicate:

A patient presents with a 2 day history of haemoptysis. Blood results show a raised urea & creatinine.

A

Goodpasture Syndrome (anti-glomerular basement membrane disease)
~ glomerulonephritis (AKI)
~ pulmonary haemorrhage (haemoptysis)

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7
Q

What is a pneumothorax?

What is the 1st line investigation?
~ If a pneumothorax is too small to be seen, what other investigation can be done?

What is the management:

a) no SOB/ < 2cm
b) SOB / > 2cm
c) unstable patients/ failure of b) twice

A

Air inside the pleural space separates the lung from the chest wall

  • *Investigations:**
    1) Erect chest xray
    2) CT thorax
  • *Management:**
    a) no treatment - should self resolve (advise follow up 2 - 4 weeks)
    b) aspiration of air → reassessment
    c) chest drain
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8
Q

What is the gold standard investigation to confirm a diagnosis of sarcoidosis & what would this show?

What other investigations would you do? (2)

What is the treatment of sarcoidosis if:

a) patient is asymptomatic
b) patient has symptoms

A

Biopsy of mediastinal lymph nodes: non-caseating granulomas with epitheloid cells

Bloods (raised serum ACE & CRP, hypercalcaemia) + chest xray

Treatment:
a) None - commonly self resolves
b) 1st line = oral steroids for 6-24m PLUS bisphosphonates (to protect their bones)
~ 2nd line = methotrexate
~ 3rd line = lung transplant

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9
Q

What is a tension pneumothorax?
~ what is the cause?

List some signs of a tension pneumothorax: (4)

What is the initial management?

What is the definitive management?

A

Tension pneumothorax: air enters the pleural space through a one way valve - during inspiration, air moves into pleural space, during expiration air cannot leave
~ Caused by trauma to the chest

  • SOB
  • Tracheal deviation away from side of pneumorthorax
  • Reduced air entry on affected side
  • Resonant to percussion on affected side
  • *Management:**
  • Initial*: insert a large bore cannula into the 2nd intercostal space in the midclavicular line
  • Definitive*: Chest drain
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10
Q

What is Croup?

What is the commonest causative organism?

What are the common presenting features of croup? (6)

How long does croup usually last for?

What is the management of croup?

A

An URTI causing oedema & swelling of the larynx.

Parainfluenza virus

~ Increased work of breathing
~ Barking cough (sounds like a seal)
~ cold symptoms
~ hoarse voice
~ +/- stridor
~ +/- mild fever

1 - 2 days

Oral dexamethasone

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11
Q

What 3 symptoms are characteristic of asthma?

A

WHEEZE

Cough

SOB

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12
Q

What are the 2 criteria’s/ tools that GP’s often use to determine a bacterial or viral cause of a sore throat?

A

CENTOR & feverPAIN

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13
Q

List some features of a pleural effusion: (3)

List 2 findings seen on a chest xray:
What other investigation would you do in a pleural effusion to determine the cause?

What is the treatment of a small effusion/ large effusion?

What is the name of an infected pleural effusion?

A
  • SOB
  • Reduced breath sounds
  • Dullness to prescussion over the effusion

Xray findings:
• Blunting of the costophrenic angles
• Fluid in the lung fissures
Pleural fluid aspirate - to determine exudate VS transudate cause

  • *Treatment:**
  • Small effusion:* conservative management
  • Large effusion:* chest drain

Infected pleural effusion = empyema

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14
Q

What is sarcoidosis?

State the ‘buzzword’ features of sarcoidosis: (6)

What results would be seen on:

a) blood tests (3)
b) chest xray

A

Sarcoidosis: a granulatomas inflammatory condition that can affect the whole body (commonest in young, black females)

Features:
• SOB
• Dry cough
• Erythmema nodosum (nodules on shins)
• Mediastinal lymphadenopathy
• Fatigue & weightloss

Bloods:
• Raised serum ACE (screening tool)
• Hypercalcaemia
• Raised CRP

Imaging:
• Chest xray: hilar lymphadenopathy

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15
Q

A 1 year old girl is brought in to A/E by her parents as they are concerned about her breathing. She has been feeling unwell with the flu over the last few days. The parents describe a barking cough. They think she has had all her immunisations. She has a high grade fever. A constant high-pitched sound on inspiration can be heard and she has a hoarse voice.

Humidified oxygen, dexamethasone and nebulised adrenaline is given. The symptoms do not improve.

What is the most likely diagnosis?

A

Bacterial Tracheitis

Always consider bacterial tracheitis in a barking cough with continuous stridor that does not resolve.

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16
Q

Granuloma’s are nodules of inflammation, - what immune cell are they full of?

A

Macrophages!

17
Q

Explain what FEV1 & FVC are:

FEV1:FVC < 75% indicates what type of respiratory disease?

FEV1:FVC > 75% indicates what type of respiratory disease?

A

FEV1: Forced expiratory volume in 1 second
~ the amount of air exhaled in1s.
~ it measures how easily air flows out of the lungs

FVC: Forced vital capacity
~ the total amount of air that someone can exhale after a full inhilation
~ it measures the lung capacity of the patient

FEV1:FVC < 75% = obstructive lung disease
~ FEV1 is reduced whereas FVC may be normal

FEV1:FVC > 75% = restrictive lung disease
~ both FEV1 & FVC are reduced so the ratio is normal/ high!

18
Q

List some common symptoms of asthma: (3)

List some common symptoms of COPD: (5)
~ state the biggest risk factor!!

A

Asthma:
• Wheeze
• Cough (worse at night)
• SOB

COPD:
• Progressive SOB
• Cough
• Sputum production
• Wheeze
• Recurrent resp infections
Risk factor: SMOKING

19
Q

Regarding pO2 & pCO2, what would be seen on a blood gas in:

a) type 1 respiratory failure
b) type 2 respiratory failure

A

Type 1 resp failure: low O2, normal CO2

Type 2 resp failure: low O2, high CO2 - respiraoty acidosis

20
Q

TB usually presents with chronic, slowly progressive symptoms. List some: (6)

What is the management of acute TB? (RIPE)
~ state the common side effects

A
  • Cough +/- haemoptysis
  • Fever/ night sweats
  • Weight loss
  • Fatigue
  • Erythema nodosum (nodules on shins)
  • Lymphaddenopathy

Management of acute TB:

R: Rifampicin (6 months)
S/E: red/ orange tears/ urine (secretions)

I: Isoniazid (6 months)
S/E: peripheral neuropathy

P: Pyrazinamide (2 months)
S/E: gout (causes high uric acid levels!)

E: Ethambutol (2 months)
S/E: colour blindness

21
Q

What is a pleural effusion?

What is the difference between exudate & transudate?

List lung causes of an exudate (3) & transduate (1):

A

Pleural effusion = fluid in the pleural cavity

Exudate: fluid contains 3g+ of protein - caused by inflammation
• Lung cancer
• Pneumonia
• TB

Transudate: fluid contains less than 3g of protein - caused by fluid shifts
• Congestive heart failure

22
Q

In what condition is there reversible airway obstruction?

What class of medications are used to treat this?

Name the medication used.

A

Asthma

Short acting beta agonists

Salbutamol

23
Q

Give 2 examples of:

a) obstructive lung diseases
b) restrictive lung diseases

Would you expect an FEV1:FVC ratio to be < or > 75% in each?

A

Obstructive lung diseases: FEV1:FVC < 75%
• COPD (permanent airway obstruction)
• Asthma (reversible airway obstruction)

Restrictive lung diseases: FEV1:FVC > 75%
• Pulmonary fibrosis (interstitial lung disease)
• Sarcoidosis

24
Q

What tool is used to assess the severity of a pneuminia?

A

CURB-65 score

25
Q

A 14 month old girl presents with 12h of increasing wheeze and respiratory effort and a 3d history of runny nose and cough.
Examination shows bilateral wheeze, no creps and sub-costal recession, a pink throat and red ears. Resp rate of 60 and temperature 37.5c

What is the likely diagnosis?

Under what age is it commonest in?

What is the management?

A

Viral induced wheeze

Commonest under 5s (especially under 3y)

Management: salbutamol (10 puffs!)

26
Q

What is the most common organism that causes infective exacerbations of COPD?

A

Haemophilus Influenzae

27
Q

List some signs of respiratory distress: (8)

A

~ Raised respiratory rate

~ Using accessory muscles of breathing

~ Intercostal & subcostal recession

~ Nasal flaring

~ Tracheal tugging

~ Cyanosis

~ Abnormal airway nosies

~ Head bobbin

28
Q

CURB-65 is used to estimate the severity of pneumonia (and thus whether to admit the patient or not).

What parameters does CURB-65 assess?
~ A score of what would require hospital admission?

A

C - confusion (1)

U - urea >7

R - resp rate >30

B - BP, systolic >90, or diastolic >60

65 - age over 65y

Score >4 requires admission

29
Q

CURB-65 is used to estimate the severity of pneumonia (and thus whether to admit the patient or not).

What parameters does CURB-65 assess?
~ A score of what would require hospital admission?

A

C - confusion (1)

U - urea >7

R - resp rate >30

B - BP, systolic >90, or diastolic >60

65 - age over 65y

Score >4 requires admission

30
Q

CURB-65 is used to estimate the severity of pneumonia (and thus whether to admit the patient or not).

What parameters does CURB-65 assess?
~ A score of what would require hospital admission?

A

C - confusion (1)

U - urea >7

R - resp rate >30

B - BP, systolic >90, or diastolic >60

65 - age over 65y

Score >4 requires admission