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Flashcards in Respiratory Drugs (Gas#4) Deck (60)
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1

Types of Bronchodilators

Anticholinergics, Beta-Adrenergic-Agonists (Sympathomimetics) & Methylxanthines

2

What do Anticholinergics do and what are they used for?

they block the vagus nerve allowing bronchodilation & they reduce mucus. used for chronic conditions (COPD) not acute

3

Do not use Anticholinergics with what type of people?

People with glaucoma, hyperthyroidism & hypertension because it is an atropine derivative

4

Ipratropium bromide (Atrovent) is what and how many times can you use it and what else is it used for?

Short Acting Anticholinergics MDI 4xqd, used also for allergic rhinitis

5

triotropium (Spiriva) and how many times can you use it?

Long acting Anticholinergics powder once a day

6

Side effects of Anticholinergics

dry mouth & throat, cough

7

What do Beta Adrenergic Agonists (Sympathomimetics) do

stimulate beta2 adrenoreceptors, dilate the bronchi, stimulate mucus clearance

8

what are Beta Adrenergic Agonists (Sympathomimetics) used for?

acute asthma attacks, prophylaxis for both exercise induced asthma and exposure to known allergies

9

Isoproterenol, Epinephrine, Ephedrine are what?

Nonselective Beta Adrenergic Agonists (Sympathomimetics)

10

Salmerol (Serevent) & formoterol (Foradil).& what are they never used for

Selective long lasting Beta Adrenergic Agonists (Sympathomimetics) Never for PRN use!

11

albuterol (proventil, accolate, ventolin), levalbuterol (Xopenex), terbutaline (Brethine)

Selective short acting Beta Adrenergic Agonists (Sympathomimetics)

12

side effects of nonselective Beta Adrenergic Agonists (Sympathomimetics)

tachycardia, arrhythmias, angina

13

side effects of selective long/short acting Beta Adrenergic Agonists (Sympathomimetics)

nervousness, anxiety, insomnia, irritability, dizziness, sweating, increased BP

14

Beta Adrenergic Agonists (Sympathomimetics) mimic what system?

sympathetic nervous system which increases BP, Resp, dilates bronchi, decreases GI & kidney flow

15

What should you watch for in a patient who is taking a Beta Adrenergic Agonists (Sympathomimetics)

respirations, BO, GI & kidneys

16

Therapeutic range for Methylaxanthines

10-20 mcg/mL

17

What are Methylaxanthines used for?

prophylaxis of asthma, used with newborns who don't breath well

18

What do Methylaxanthines do?

increase bronchodilation, decrease histamine release, stimulate ciliary transport of mucus, improve contractility of diaphram, increases CO

19

if a patient who smokes is on a Methylaxanthine, how does that change the prescription?

dose may be higher because cigarettes increase the metabolism of the drug.

20

what things increase the toxicity of Methylaxanthines

coffee, beta blockers, CCB, antibiotics, alcohol, BC with estrogen

21

what do you monitor when a patient is one Methylaxanthines

blood levels

22

when should you give a Methylaxanthines

during the day to prevent insomnia and take with food to prevent GI upset

23

what side effects do Methylaxanthines have on the CNS, GI and Cardiac

CNS:nervousness, insomnia, HA, dizziness, tremors(late sign), GI, Nausea (1st sign), vomiting, anorexia, Cardiac: tachycardia, angina, hypotension

24

what things decrease the therapeutic level of Methylaxanthines?

smoking, antiseizure meds & Benzos

25

When do corticosteriods take effect?

can take days

26

what do corticosteriods put you at risk for?

hypokalemia, hypocalemia, hyertension, increased BS

27

What is the first/late sign that you have reached toxic xathine levels?

1st: N/v 2nd; tremors

28

Mast cell stabilizers are more effective in what kinds of people?

children rather than old people

29

Do mast cell stabilizers have a bronchodilating effect?

no

30

Inhibits leukotrine receptors/inhibits leukotrine synthesis

receptors: singular
Synthesis: zyflo