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Flashcards in Respiratory pathology Deck (65)
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1

PaO2 of respiratory failure

8

2

PaO2 of type 1 respiratory failure, and what is driving it?

3

PaO2 of type 2 respiratory failure, and what is driving it?

>6.3kPa, hypercapnic drive

4

Two types of carcinoma

Small cell and non small cell

5

4 types non small cell

Squamous
Undifferentiated large cell
Adenocarcinoma
Large cell neuroendocrine

6

90% smokers have which type of lung cancer?

Squamous small cell carcinoma

7

Which cancer can mimic pneumonia?

Bronchioloalveolar carcinoma

8

Neuroendocrine tumours are detected using what?

CD56 and neurosecretory granule proteins- chromogranin, synaptophysin

9

4 features of typical carcinoid tumours

No necrosis, bland
Distant mets are rare
Not assoc with smoking
May occlude bronchioles

10

Thyroid transcription factor is expressed by which 3 carcinomas?

Adenocarcinoma
Undifferentiated large cell carcinoma
Small cell

11

Small cell carcinomas also secrete what?

ACTH and ADH

12

What does TNM staging include as well as the usual?

Atelectasis of lobe/lung

13

2 causes of pleural effusion

Inflammatory-exudate
Congestive heart failure- transudate

14

Which colour asbestos is the worst?

Blue (or brown but blue worst)

15

Signs of mesothelioma?

Small plaques/nodules on parietal pleura
Effusion

16

What type of cells in mesothelioma

Spindle and epitheliod

17

What pathogen causes pneumonia in the elderly, diabetics and alcoholics?

Klebsiella pneumoniae

18

What pathogen causes pneumonia in the elderly, diabetics and alcoholics?

Klebsiella pneumoniae

19

PaO2 of type 1 respiratory failure, and what is driving it?

20

Complications of bronchiectasis?

Pneumonia
Septicaemia
Metastatic infection
Amyloidosis

21

Two types of carcinoma

Small cell and non small cell

22

4 types non small cell

Squamous
Undifferentiated large cell
Adenocarcinoma
Large cell neuroendocrine

23

90% smokers have which type of lung cancer?

Squamous small cell carcinoma

24

Which cancer can mimic pneumonia?

Bronchioloalveolar carcinoma

25

Neuroendocrine tumours are detected using what?

CD56 and neurosecretory granule proteins- chromogranin, synaptophysin

26

4 features of typical carcinoid tumours

No necrosis, bland
Distant mets are rare
Not assoc with smoking
May occlude bronchioles

27

Thyroid transcription factor is expressed by which 3 carcinomas?

Adenocarcinoma
Undifferentiated large cell carcinoma
Small cell

28

Small cell carcinomas also secrete what?

ACTH and ADH

29

What does TNM staging include as well as the usual?

Atelectasis of lobe/lung

30

Symptoms and signs of interstitial lung disease

Slowly increasing dyspnoea
Clubbing
Fine crackles
Dry cough