Respiratory Pathology - 6 (Larynx, ears, neck) Flashcards
(40 cards)
What are 3 squamous lesions of the larynx?
- Vocal cord nodule
- Laryngeal squamous papilloma
- Laryngeal Carcinoma
What are 3 squamous lesions of the larynx?
- Vocal cord nodules
- Laryngeal Squamous Papilloma
- Laryngeal Carcinoma
What are Vocal Cord Nodules and who are they common in?
- Common in singer’s
= Soft tissue expansion underlying the vocal fold
Appearance of Vocal Cord Nodules?
Soft and translucent
Histologic appearance of Vocal Cord Nodules?
Edema and loose stroma underlie benign squamous epithelium
Edema and loose stroma underlie benign squamous epithelium
Vocal Cord Nodule
What causes a vocal cord nodule?
Soft tissue expansion underlying the vocal fold (rienke’s space)
A Laryngeal Squamous Papilloma is a benign neoplasm. What is it associated with - molecularly and other?
- HPV 6 and 11
- Recurrent respiratory Papillomatosis
Appearance of a Laryngeal Squamous Papilloma?
Friable papillary masses
Histologic appearance of Laryngeal Squamous Papilloma?
Benign or mildly atypical squamous epithelium with multiple papillae
A Laryngeal Squamous Papilloma can be solitary or associated with recurrent respiratory papillomatosis. What is that?
Children associated with HPV 6 and 11 usually acquired during birth
- Risk factors:
1. Mothers < 20
2. Vaginal delivery
3. First child
- Risk factors:
What type of Carcinoma is a Laryngeal Carcinoma and in what patient population?
Men > 60
= Squamous carcinoma
What are 3 synergistic risk factors for a Laryngeal Carcinoma?
- Smoking
- Alcohol
- HPV infection
What 3 pathogens often cause Otitis Media?
SMH
- Streptococcus Pneumoniae
- Moraxella Catarrhalis
- Haemophilus Influenzae
What 3 pathogens often cause Otitis Media?
SMH
- Streptococcus Pneumoniae
- Moraxella Catarrhalis
- Haemophilus Influenzae
In what patients is Chronic Otitis Media common?
Diabetics
What pathogen often causes Chronic Otitis Media in diabetics?
Pseudomonas Aeruginosa
What can Chronic Otitis Media give rise to?
Cholesteatoma
What is a Cholesteatoma and when is it seen?
- Cystic lesion
- - Seen with Chronic Otitis Media in diabetic patients sometimes
What can a cholesteatoma do to adjacent bone?
Erode it by growing
– Reactive process
What is the Histologic Appearance of a Cholesteatoma?
Trapped Keratin debris inside benign squamous epithelium
Trapped keratin debris inside benign squamous epithelium
Cholesteatoma - cystic lesion
How is Otosclerosis inherited?
Autosomal Dominant
What is Otosclerosis?
Bony deposition at the stapedial footplate that impairs vibrations needed for hearing
