Respiratory-theophylline

Question 1

Theophylline indications

Answer 1

asthma, bronchitis, emphysema, COPD

Question 2

Theophylline moa

Answer 2

Competitively inhibits type III and type IV phosphodiesterase (PDE), the enzyme responsible for breaking down cyclic AMP in smooth muscle cells, possibly resulting in bronchodilation. Theophylline also binds to the adenosine A2B receptor and blocks adenosine mediated bronchoconstriction.

Question 3

Theophylline side effects

Answer 3

increased urine, cardio (arrhythmia, fainting, chest pain),

Question 4

Theophylline cautions

Answer 4

hypertension, stomach ulcers, epilepsy, cardio disease