RESTING POTENTIAL IL/ PSW Flashcards
(33 cards)
Fluid
components of cell membrane can move positions and move closer or farther away from each other
degree of fluidity is affected
temp, chloestrol, saturated and unssaturated fatty acids
mosaicism
cell membrane is made up of other components other than phospholipids such as chloestrol glycoproteins glycolipids
what does ficks law describe
passive diffusion of molevules from an area of high concentration to low concentration passively down the concentration gradientgs
Ji
flux of a ion
Di
diffusion coefficent
A
cross sectional area
C1-C2- concentration difference
X
distance over which diffusion takes place
Jx=Px (Xo-X1)
Px = permeability coefficent Xo-Xi difference in the concentration of molecule x inside and outside the cell
when concentration of molecule x is higher outside the cell (Xo) compared to inside (Xi) the flux is
positive
when Xi is greater than Xo the flux is
negative
non gated channels
leakage channels aka pores are conduits that are always open
gated channels
pores that open and close in response to certain changes like voltage mechanical stretch chemical ligand binding etc
tetramers 4 subunits
voltage gates Na+, Ca++ and K_ , Ca release channels
Pentamers 5 subunits
nicotininc acetylcholine receptor channels triggered by binding molecules
hexamers 6 subunits
half of a gap junction channel called a connexon made of 6 connecins
Gap junction chanells are abundant in the heart ensuring fast and synchronized electrical signal to prevent ___
irregular heartbeats
voltage gated channels
open and close due to changes in membrane potential
ligand gated channels
open and close because of molecules binding to them
a positive ion departing the cell created a positive current while a positive ion entering produces a
negative current
how does resting membrane potential persist with ions continually leaking in and out
the Na+/K+ ATPase
T or F
conductance is always positive
T
nernst equation
The actual reduction potential of a half cell
will vary with the concentration of each chemical species in the cell. The relationship between the reduction potential E and the standard reduction potential E° is given by the following equation (also called the Nernst
equation)