RESTING POTENTIAL IL/ PSW Flashcards

1
Q

Fluid

A

components of cell membrane can move positions and move closer or farther away from each other

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2
Q

degree of fluidity is affected

A

temp, chloestrol, saturated and unssaturated fatty acids

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3
Q

mosaicism

A

cell membrane is made up of other components other than phospholipids such as chloestrol glycoproteins glycolipids

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4
Q

what does ficks law describe

A

passive diffusion of molevules from an area of high concentration to low concentration passively down the concentration gradientgs

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5
Q

Ji

A

flux of a ion

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6
Q

Di

A

diffusion coefficent

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7
Q

A

A

cross sectional area

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8
Q

C1-C2- concentration difference

A
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9
Q

X

A

distance over which diffusion takes place

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10
Q

Jx=Px (Xo-X1)

A

Px = permeability coefficent Xo-Xi difference in the concentration of molecule x inside and outside the cell

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11
Q

when concentration of molecule x is higher outside the cell (Xo) compared to inside (Xi) the flux is

A

positive

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12
Q

when Xi is greater than Xo the flux is

A

negative

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13
Q

non gated channels

A

leakage channels aka pores are conduits that are always open

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14
Q

gated channels

A

pores that open and close in response to certain changes like voltage mechanical stretch chemical ligand binding etc

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15
Q

tetramers 4 subunits

A

voltage gates Na+, Ca++ and K_ , Ca release channels

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16
Q

Pentamers 5 subunits

A

nicotininc acetylcholine receptor channels triggered by binding molecules

17
Q

hexamers 6 subunits

A

half of a gap junction channel called a connexon made of 6 connecins

18
Q

Gap junction chanells are abundant in the heart ensuring fast and synchronized electrical signal to prevent ___

A

irregular heartbeats

19
Q

voltage gated channels

A

open and close due to changes in membrane potential

20
Q

ligand gated channels

A

open and close because of molecules binding to them

21
Q

a positive ion departing the cell created a positive current while a positive ion entering produces a

A

negative current

22
Q

how does resting membrane potential persist with ions continually leaking in and out

A

the Na+/K+ ATPase

23
Q

T or F
conductance is always positive

A

T

24
Q

nernst equation

A

The actual reduction potential of a half cell
will vary with the concentration of each chemical species in the cell. The relationship between the reduction potential E and the standard reduction potential E° is given by the following equation (also called the Nernst
equation)

25
Q

at steady state the net current is zero

A

INa + IK =0

26
Q

ion flux and direction are guided by the driving force

A

Vm-Eeq

27
Q

positive or negative current informs us about the ion flow direction

A

T

28
Q

cations a positive current denotes ___ flow while a negative current signfiies ___ flow and reverse for anions

A

outward
inward

29
Q

ohms law

A

voltage = current * Resistance

30
Q

permeability is defined as a physical property of the membrane and is dependant on the _____

A

leak channels and ion channels

31
Q

what is inverse of resistance and is an electrical measure

A

Conductance

32
Q

T or false
with 0 voltage the conductance will be 0 permeability however will not in cases where a voltage exists, conductance and permeability become the same thing

A

T

33
Q

in the situation where there are equal amounts of Na and K channels, the voltage 0 as the ____ potential of ___ and ___

A

electric potential of Na and K cancel each other out.