Reversible Enzyme Inhibition Exam 2

Question 1

Competitive

“Y” so competitive?
(Classical, Nonclassical)

Answer 1

inhibitor binds to free enzyme
Km Increases
Vmax No Change
intersect on Y-axis

Question 2

Noncompetitive

N & n - binds to two things

Answer 2

inhibitor binds free enzyme and enzyme substrate
Km No Change
Vmax Decreases
Intersect on X-axis

Question 3

Uncompetitive

Answer 3

inhibitor binds to enzyme substrate complex only
Km Decreases Proportionally
Vmax Decreases Proportionally
Parallel Lines